Open access peer-reviewed Edited volume

Understanding Tuberculosis

Global Experiences and Innovative Approaches to the Diagnosis

Institut Germans Trias i Pujol (IGTP). Catalonia

Mycobacterium tuberculosis is a disease that is transmitted through aerosol. This is the reason why it is estimated that a third of humankind is already infected by Mycobacterium tuberculosis. The vast majority of the infected do not know about their status. Mycobacterium tuberculosis is a silent pathogen, causing no symptomatology at all during the infection. In addition, infected people cannot cause further infections. Unfortunately, an estimated 10 per cent of the infected population has the probability to develop the disease, making it very difficult to eradicate. Once in this stage, the bacilli can be transmitted to other persons and the development of clinical symptoms is very progressive. Therefore the diagnosis, especially the discrimination between infection and disease, is a real challenge. In this book, we present the experience of worldwide specialists on the diagnosis, along with its lights and shadows.

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Understanding TuberculosisGlobal Experiences and Innovative Approaches to the DiagnosisEdited by Pere-Joan Cardona

Published: February 15th 2012

DOI: 10.5772/1483

ISBN: 978-953-307-938-7

Books open for chapter submissions

91866 Total Chapter Downloads

14 Crossref Citations

34 Web of Science Citations

52 Dimensions Citations

chapters		Downloads
Open access peer-reviewed 1. Clinical Laboratory Diagnostics for Mycobacterium tuberculosis By N. Esther Babady and Nancy L. Wengenack		16674
Open access peer-reviewed 2. Laboratory Diagnosis of Latent and Active Tuberculosis Infections in Trinidad & Tobago and Determination of Drug Susceptibility Profile of Tuberculosis Isolates in the Caribbean By Patrick Eberechi Akpaka and Shirematee Baboolal		1840
Open access peer-reviewed 3. Tuberculosis is Still a Major Challenge in Africa By Simeon I.B. Cadmus, Osman El Tayeb and Dick van Soolingen		1312
Open access peer-reviewed 4. Tuberculosis in Saudi Arabia By Sahal Al-Hajoj		6954
Open access peer-reviewed 5. Diagnosis of Mycobacterium tuberculosis By Faten Al-Zamel		3049
Open access peer-reviewed 6. Diagnosis of Smear-Negative Pulmonary Tuberculosis in Low-Income Countries: Current Evidence in Sub-Saharan Africa with Special Focus on HIV Infection or AIDS By Claude Mambo Muvunyi and Florence Masaisa		4358
Open access peer-reviewed 7. Immunologic Diagnosis of Neurotuberculosis By Iacob Simona Alexandra, Banica Dorina, Iacob Diana Gabriela, Panaitescu Eugenia, Radu Irina and Cojocaru Manole		1994
Open access peer-reviewed 8. Diagnostic Methods for Mycobacterium tuberculosis and Challenges in Its Detection in India By Shamsher S. Kanwar		4786
Open access peer-reviewed 9. Management of TB in HIV Subjects, the Experience in Thailand By Attapon Cheepsattayakorn		1443
Open access peer-reviewed 10. Mycobacterium tuberculosis: Biorisk, Biosafety and Biocontainment By Wellman Ribón		3549
Open access peer-reviewed 11. New Diagnostics for Mycobacterium tuberculosis By Michaela Lucas, Andrew Lucas and Silvana Gaudieri		1597
Open access peer-reviewed 12. Nanodiagnostics for Tuberculosis By Bruno Veigas, Gonçalo Doria and Pedro V. Baptista		3067
Open access peer-reviewed 13. Sputum Smear Microscopy for Tuberculosis: Evaluation of Autofocus Functions and Automatic Identification of Tuberculosis Mycobacterium By Cicero F. F. Costa Filho and Marly G. F. Costa		4094
Open access peer-reviewed 14. The Use of Phage for Detection, Antibiotic Sensitivity Testing and Enumeration By Catherine Rees and George Botsaris		3201
Open access peer-reviewed 15. Molecular Imaging in TB: From the Bench to the Clinic By Nuria Andreu, Paul T. Elkington and Siouxsie Wiles		1934
Open access peer-reviewed 16. Data Mining Techniques in the Diagnosis of Tuberculosis By T. Asha, S. Natarajan and K. N. B. Murthy		2712
Open access peer-reviewed 17. Immunological Diagnosis of Active and Latent TB By Beata Shiratori, Hiroki Saitoh, Umme Ruman Siddiqi, Jingge Zhao, Haorile Chagan-Yasutan, Motoki Usuzawa, Chie Nakajima, Yasuhiko Suzuki and Toshio Hattori		5311
Open access peer-reviewed 18. Immune Diagnosis of Tuberculosis Through Novel Technologies By Miguel A. Arroyo-Ornelas, Ma. Concepción Arenas-Arrocena, Horacio V. Estrada, Victor M. Castaño and Luz M. López-Marín		1632
Open access peer-reviewed 19. Exosomes: New Tuberculosis Biomarkers – Prospects From the Bench to the Clinic By Nicole A. Kruh-Garcia, Jeff S. Schorey and Karen M. Dobos		3635
Open access peer-reviewed 20. Molecular Techniques for Identification of Species of the Mycobacterium tuberculosis Complex: The use of Multiplex PCR and an Adapted HPLC Method for Identification of Mycobacterium bovis and Diagnosis of Bovine Tuberculosis By Eduardo Eustáquio de Souza Figueiredo, Carlos Adam Conte Júnior, Leone Vinícius Furlanetto, Flávia Galindo Silvestre Silva, Rafael Silva Duarte, Joab Trajano Silva, Walter Lilenbaum and Vânia Margaret Flosi Paschoalin		2709
Open access peer-reviewed 21. Survey and Molecular Characterization of Drug- Resistant M. tuberculosis Clinical Isolates from Zunyi, Guizhou Province of China By Ling Chen, Hong Zhang, Jian-Yong Zhang, Na-Na Li, Mei Liu, Zhao-Jing Zong, Jian-Hua Wang and Sheng-Lan Wang		1697
Open access peer-reviewed 22. Molecular Biological Techniques for Detection of Multidrug Resistant Tuberculosis (MDR) and Extremely Drug Resistant Tuberculosis (XDR) in Clinical Isolates of Mycobacterium tuberculosis By K.L. Therese, R. Gayathri and H.N. Madhavan		2192
Open access peer-reviewed 23. Detection of Mycobacterium tuberculosis and Drug Resistance: Opportunies and Challenges in Morocco By I. Chaoui1, M. Abid, My. El Messaoudi and My. D. El Mzibri		8754
Open access peer-reviewed 24. Pattern of Circulating Mycobacterium tuberculosis Strains in Sri Lanka By Dhammika Magana-Arachchi		1520
Open access peer-reviewed 25. Health Interventions to Improve the Medication Efficacy in Tuberculosis Treatment By Jean Leandro dos Santos, Chung Man Chin, Ednir de Oliveira Vizioli, Fernando Rogério Pavan and Luiz Antonio Dutra		1852

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