Open access peer-reviewed Edited Volume

Stem Cell Biology in Normal Life and Diseases

Edited by Kamran Alimoghaddam

Tehran University of Medical Sciences, Iran

Stem cells have a prominent role in normal life and also in pathogenesis of disorders. Today, these cells are clinically applicable in hematopoietic stem cell transplantation but expansion of their application in many more disorders needs more work. For safe and effective application of these cells, we need better knowledge of their biology, their interaction with other cells (especially supporting niche cells), growth, maturation and also immigration of stem cells through body in normal and abnormal conditions. Also for clinical application we need to understand better, their separation methods and safe manipulation. This book is written to clarify some aspects of stem cell biology, their characteristics, assessment of damage to cells during ex vivo manipulation and also their role in a model of cancers (chronic myeloid leukemia).

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Stem Cell Biology in Normal Life and DiseasesEdited by Kamran Alimoghaddam

Published: May 8th 2013

DOI: 10.5772/46173

ISBN: 978-953-51-1107-8

eBook (PDF) ISBN: 978-953-51-7141-6

Copyright year: 2013

Books open for chapter submissions

22844 Total Chapter Downloads

6 Crossref Citations

13 Web of Science Citations

15 Dimensions Citations


Open access peer-reviewed

1. Regulators of the Proliferation of Hematopoietic Stem and Progenitor Cells During Hematopoietic Regeneration

By Yasushi Kubota and Shinya Kimura


Open access peer-reviewed

2. Hematopoietic Stem Cell Niche: Role in Normal and Malignant Hematopoiesis

By Sergio P. Bydlowski, Debora Levy, Jorge M.L. Ruiz and Juliana Pereira


Open access peer-reviewed

3. Expression Profile of Galectins (Gal-1, Gal-9, Gal-11 and Gal-13) in Human Bone Marrow Derived Mesenchymal Stem Cells in Different Culture Mediums

By Faouzi Jenhani


Open access peer-reviewed

4. Canonical HSC Markers and Recent Achievements

By Takao Sudo, Takafumi Yokota, Tomohiko Ishibashi, Michiko Ichii, Yukiko Doi, Kenji Oritani and Yuzuru Kanakura


Open access peer-reviewed

5. Hematopoietic Stem Cells and Response to Interferon

By Atsuko Masumi


Open access peer-reviewed

6. Stem Cell Predictive Hemotoxicology

By Holli Harper and Ivan N. Rich


Open access peer-reviewed

7. Stem Cell-Based (Auto)Grafting: From Innovative Research Toward Clinical Use in Regenerative Medicine

By Bela Balint, Slobodan Obradovic, Milena Todorovic, Mirjana Pavlovic and Biljana Mihaljevic


Open access peer-reviewed

8. Hematopoietic Stem Cells in Chronic Myeloid Leukemia

By Antonieta Chávez-González, Sócrates Avilés-Vázquez, Dafne Moreno-Lorenzana and Héctor Mayani


Open access peer-reviewed

9. Role of Bone Marrow Derived Mesenchymal Stem Cells in Management of Graft Versus Host Disease

By Aisha Nasef


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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