Open access peer-reviewed Edited Volume

Role of Neutrophils in Disease Pathogenesis

Edited by Maitham Khajah

Kuwait University

This book highlights the important role of neutrophils in health as well as in the pathogenesis of various diseases. Section 1 provides a general background information regarding the mechanisms and various triggers of neutrophil extracellular traps (NETs) formation and their role in various infectious and noninfectious diseases (such as postinjury inflammation). Section 2 provides recent evidence regarding the role of neutrophils in the pathogenesis as well as a therapeutic target for selected disease conditions such as periodontal diseases, rheumatoid arthritis, and cystic fibrosis. Section 3 describes the anti-inflammatory properties of neutrophils with focus regarding their role in graft versus host disease. This book provides a wider picture with regard to the importance of this immune cell type in various diseases with focus on one of its recently discovered properties, NETs. Therapeutic targets aimed to modulate neutrophil functions might provide novel approaches in the treatment of various diseases of infectious and noninfectious origin.

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Role of Neutrophils in Disease PathogenesisEdited by Maitham Khajah

Published: June 7th 2017

DOI: 10.5772/65581

ISBN: 978-953-51-3196-0

Print ISBN: 978-953-51-3195-3

eBook (PDF) ISBN: 978-953-51-4800-5

Copyright year: 2017

Books open for chapter submissions

10440 Total Chapter Downloads

12 Crossref Citations

15 Web of Science Citations

18 Dimensions Citations


Open access peer-reviewed

1. Neutrophil Extracellular Traps in Infectious Human Diseases

By Marcin Zawrotniak, Andrzej Kozik and Maria Rapala‐Kozik


Open access peer-reviewed

2. Beneficial and Deleterious Effects of Neutrophil Extracellular Traps on Infection

By Maximina B. Moreno-Altamirano, Christian E. Cruz-Gómez and Lluvia E. López-Luis


Open access peer-reviewed

3. The Role of Neutrophil Extracellular Traps in Post‐Injury Inflammation

By Eszter Tuboly, Gabrielle D. Briggs and Zsolt J. Balogh


Open access peer-reviewed

4. Neutrophil Role in Periodontal Disease

By Carlos Rosales and Eileen Uribe‐Querol


Open access peer-reviewed

5. Neutrophils in Rheumatoid Arthritis: A Target for Discovering New Therapies Based on Natural Products

By Elaine Cruz Rosas, Luana Barbosa Correa and Maria das Graças Henriques


Open access peer-reviewed

6. Role of Neutrophils in Cystic Fibrosis Lung Disease

By Massimo Conese, Stefano Castellani, Susanna D’Oria, Sante Di Gioia and Pasqualina Montemurro


Open access peer-reviewed

7. Neutrophils Plasticity: The Regulatory Interface in Various Pathological Conditions

By Suelen Martins Perobelli, Triciana Gonçalves Silva and Adriana Bonomo


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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