Open access peer-reviewed Edited Volume

Quinazolinone and Quinazoline Derivatives

One of the problems with modern public health is target searching for new highly effective medicinal preparations. Among those medicinal preparations are the natural and synthetic origins of quinazolinone-4 derivatives. Quinazolinone derivatives are reported to be physiologically and pharmacologically active. They also exhibit a wide range of activities such as anticonvulsant, antiinflammatory, antifungal, antimalarial, and sedative properties. Some of these compounds are identified as drugs used as diuretics, vasodilators, and antihypertensive agents. Moreover, sulfonamide derivatives have been widely used as bacteriostatic agents. Prompted by the above-mentioned facts and in conjunction with our ongoing program on the utility of readily obtainable starting material for the synthesis of heterocyclic systems of biological interest, we have decided to synthesize a series of quinazolinone derivatives having sulfonamide moiety with a potentially wide spectrum of biological responses.

Read more >Order hardcopy
Quinazolinone and Quinazoline DerivativesEdited by Ali Gamal Al-kaf

Published: May 6th 2020

DOI: 10.5772/intechopen.85315

ISBN: 978-1-83880-140-3

Print ISBN: 978-1-83880-139-7

eBook (PDF) ISBN: 978-1-83880-053-6

Copyright year: 2020

Books open for chapter submissions

2287 Total Chapter Downloads

1 Crossref Citations

2 Dimensions Citations


Open access peer-reviewed

1. Introductory Chapter: The Newest Research in Quinazolinone and Quinazoline Derivatives

By Ali Gamal Al-kaf


Open access peer-reviewed

2. Biological Activity of Quinazolinones

By Awwad A. Radwan and Fars K. Alanazi


Open access peer-reviewed

3. Synthesis of Quinazoline and Quinazolinone Derivatives

By Heba E. Hashem


Open access peer-reviewed

4. 4(3H)-Quinazolinone Derivatives: Syntheses, Physical Properties, Chemical Reaction, and Biological Properties

By Samir Y. Abbas


Open access peer-reviewed

5. Quinazolinone and Quinazoline Derivatives: Synthesis and Biological Application

By Satyendra Mishra


Open access peer-reviewed

6. Synthesis and Pharmacological Research Regarding New Compounds with Quinazolin-4-One Structure

By Cornel Chiriţă, Carmen Limban, Diana Camelia Nuţă, Emil Ştefănescu, Simona Negreş, Cristina Elena Zbârcea, Cristina Daniela Marineci, Oana Cristina Șeremet, Mihaela Trandafir (Bratu), Alexandru Vasile Missir and Ileana Cornelia Chiriţă


Open access peer-reviewed

7. Quinazoline Based Synthesis of some Heterocyclic Schiff Bases

By Sainath Bhanudas Zangade


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

Order a hardcopy of the Edited Volume

Free shipping with DHL Express

Hardcover (ex. VAT)£119

Order now

Residents of European Union countries need to add a Book Value-Added Tax of 5%. Institutions and companies, registered as VAT taxable entities in their own EU member state, will not pay VAT by providing IntechOpen with their VAT registration number. This is made possible by the EU reverse charge method.

Special discount for IntechOpen contributors

All IntechOpen contributors are offered special discounts starting at 40% OFF available through your personal dashboard

Login and purchase