Open access peer-reviewed Edited Volume

Quantitative Structure-activity Relationship

Edited by Fatma Kandemirli

Kastamonu University

The book, which is related to QSAR in sciences, is divided into five main chapters. The first chapter is the Introductory chapter. The second chapter aims to provide an update of the recent advances in the field of rational design of PDE inhibitors. The third chapter includes designing a series of peptidic inhibitors that possessed a substrate transition-state analog and evaluating the structure-activity relationship of the designed inhibitors, based on docking and scoring, using the docking simulation software Molecular Operating Environment. The aim of the forth chapter is to develop structure-property relationships for the qualitative and quantitative prediction of the reverse-phase liquid chromatographic retention times of chlorogenic acids. The final chapter aims to determine the model of interactions between the natural compounds with anti-inflammatory molecular target by molecular docking analysis.

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Quantitative Structure-activity RelationshipEdited by Fatma Kandemirli

Published: August 30th 2017

DOI: 10.5772/65597

ISBN: 978-953-51-3410-7

Print ISBN: 978-953-51-3409-1

eBook (PDF) ISBN: 978-953-51-4680-3

Copyright year: 2017

Books open for chapter submissions

5553 Total Chapter Downloads

3 Crossref Citations

1 Web of Science Citations

8 Dimensions Citations


Open access peer-reviewed

1. Introductory Chapter: Some Quantitative Structure Activity Relationship Descriptor

By Fatma Kandemirli


Open access peer-reviewed

2. Computational Approaches in the Development of Phosphodiesterase Inhibitors

By Anand Gaurav, Ming Xing and Mayasah Al‐Nema


Open access peer-reviewed

3. Discovery of BACE1 Inhibitors for the Treatment of Alzheimer’s Disease

By Yoshio Hamada and Yoshiaki Kiso


Open access peer-reviewed

4. QSRP Prediction of Retention Times of Chlorogenic Acids in Coffee by Bioplastic Evolution

By Francisco Torrens and Gloria Castellano


Open access peer-reviewed

5. Molecular Docking Analysis: Interaction Studies of Natural Compounds to Anti-inflammatory Targets

By Rina Herowati and Gunawan Pamudji Widodo


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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