Open access peer-reviewed Edited volume

Progress in Understanding Cystic Fibrosis

Congenital defects in humans are of greater concern, and in that line, cystic fibrosis (CF) has been one of the most complex diseases posing treatment challenge till date. Though it is a chronic condition, CF is closely associated with dysfunction of various organ systems of the human body, which in turn results in secondary infections by microbes. Decades of research by scientists worldwide has narrowed down the cause of CF to a single target gene. But the complexity of the disease is the prime impediment to finding a single-shot cure. Fortunately, the multidisciplinary approach toward understanding and management of the CF condition has certainly increased the level of life expectancy among CF patients. In particular, the "omics" and the "systems biology" approach have greatly widened the focal area for better understanding of the disease. This book includes a collection of interesting chapters contributed by eminent scientists around the world who have been striving to improve the life of those affected by CF.

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Progress in Understanding Cystic FibrosisEdited by Dinesh Sriramulu

Published: July 12th 2017

DOI: 10.5772/63263

ISBN: 978-953-51-3292-9

Print ISBN: 978-953-51-3291-2

Books open for chapter submissions

1683 Total Chapter Downloads

2 Dimensions Citations

chaptersDownloads

Open access peer-reviewed

1. CFTR Involvement in Cell Migration and Epithelial Restitution

By Scott M. O'Grady

261

Open access peer-reviewed

2. Cystic Fibrosis–Related Diabetes

By Bernadette Prentice, Shihab Hameed, Chee Y. Ooi, Charles F. Verge and John Widger

92

Open access peer-reviewed

3. The Cystic Fibrosis Airway Microbiome and Pathogens

By Ibrahim A. Janahi and Abdul Rehman

224

Open access peer-reviewed

4. Burkholderia cepacia Complex Infections Among Cystic Fibrosis Patients: Perspectives and Challenges

By Jorge H. Leitão, Joana R. Feliciano, Sílvia A. Sousa, Tiago Pita and Soraia I. Guerreiro

311

Open access peer-reviewed

5. Pseudomonas aeruginosa Extracellular Secreted Molecules Have a Dominant Role in Biofilm Development and Bacterial Virulence in Cystic Fibrosis Lung Infections

By Theerthankar Das and Jim Manos

241

Open access peer-reviewed

6. Structure‐Function Relationships of Rhamnolipid and Exopolysacharide Biosurfactants of Pseudomonas aeruginosa as Therapeutic Targets in Cystic Fibrosis Lung Infections

By Milena G. Rikalovic, Natasa S. Avramovic and Ivanka M. Karadzic

303

Open access peer-reviewed

7. Anti‐PcrV Immunization for Pseudomonas aeruginosa Pneumonia in Cystic Fibrosis

By Yoshifumi Naito, Kiyoshi Moriyama and Teiji Sawa

251

Edited volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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