Open access peer-reviewed Edited Volume

Point Mutation

Edited by Colin Logie

Radboud University Nijmegen, Netherlands

This book concerns the signatures left behind in chromosomes by the forces that drive DNA code evolution in the form of DNA nucleotide substitutions. Since the genetic code predetermines the molecular basis of life, it could have been about any aspect of biology. As it happens, it is largely about recent adaptation of pathogens and their human host. Nine chapters are medically oriented, two are bioinformatics-oriented and one is technological, describing the state of the art in synthetic point mutagenesis. What stands out in this book is the increasing rate at which DNA data has been amassed in the course of the past decade and how knowledge in this vibrant research field is currently being translated in the medical world.

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Point MutationEdited by Colin Logie

Published: March 21st 2012

DOI: 10.5772/2153

ISBN: 978-953-51-0331-8

eBook (PDF) ISBN: 978-953-51-5250-7

Copyright year: 2012

Books open for chapter submissions

36234 Total Chapter Downloads

1 Crossref Citations

6 Web of Science Citations

6 Dimensions Citations


Open access peer-reviewed

1. Point Mutations, Their Transition Rates and Involvements in Human and Animal Disorders

By Viliam Šnábel


Open access peer-reviewed

2. Bioinformatical Analysis of Point Mutations in Human Genome

By Branko Borštnik and Danilo Pumpernik


Open access peer-reviewed

3. Estimating Human Point Mutation Rates from Codon Substitution Rates

By Kazuharu Misawa


Open access peer-reviewed

4. Point Mutations and Antiviral Drug Resistance

By José Arellano-Galindo, Blanca Lilia Barron, Yetlanezi Vargas-Infante, Enrique Santos-Esteban, Emma del Carmen Herrera-Martinez, Norma Velazquez-Guadarrama and Gustavo Reyes-Teran


Open access peer-reviewed

5. Point Mutations Associated with HIV-1 Drug Resistance, Evasion of the Immune Response and AIDS Pathogenesis

By Makobetsa Khati and Laura Millroy


Open access peer-reviewed

6. Recombination and Point Mutations in Type G Rotavirus Strains: The Challenges of Vaccine Development

By Abid Nabil Ben Salem, Rouis Zyed, Buesa Javier and Aouni Mahjoub


Open access peer-reviewed

7. Molecular Attenuation Process in Live Vaccine Generation for Arenaviruses

By Sandra Elizabeth Goñi and Mario Enrique Lozano


Open access peer-reviewed

8. Mutational Polymorphism in the Bacterial Topoisomerase Genes Driven by Treatment with Quinolones

By Maja Velhner and Dragica Stojanović


Open access peer-reviewed

9. Point Mutation in Surveillance of Drug-Resistant Malaria

By Sungano Mharakurwa


Open access peer-reviewed

10. Correlations with Point Mutations and Severity of Hemolitic Anemias: The Example of Hereditary Persistence of Fetal Hemoglobin with Sickle Cell Anemia and Beta Thalassemia

By Anderson Ferreira da Cunha, Iran Malavazi, Karen Simone Romanello and Cintia do Couto Mascarenhas


Open access peer-reviewed

11. Point Mutations That Reduce Erythrocyte Resistance to Oxidative Stress

By Dmitriy Volosnikov and Elena Serebryakova


Open access peer-reviewed

12. Point Mutations in Ferroportin Disease: Genotype/Phenotype Correlation

By Riad Akoum


Open access peer-reviewed

13. p53: Point Mutations, SNPs and Cancer

By Ming Fang, Iva Simeonova and Franck Toledo


Open access peer-reviewed

14. Transgenerational Effects of Maternal Nicotine Exposure During Gestation and Lactation on the Respiratory System

By G. S. Maritz


Open access peer-reviewed

15. Synthetic Point Mutagenesis

By Roman A.G. Schaeken, Joke J.F.A. van Vugt and Colin Logie


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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