Example of aggregation of functions (output – input).
\\n\\n
Released this past November, the list is based on data collected from the Web of Science and highlights some of the world’s most influential scientific minds by naming the researchers whose publications over the previous decade have included a high number of Highly Cited Papers placing them among the top 1% most-cited.
\\n\\nWe wish to congratulate all of the researchers named and especially our authors on this amazing accomplishment! We are happy and proud to share in their success!
Note: Edited in March 2021
\\n"}]',published:!0,mainMedia:null},components:[{type:"htmlEditorComponent",content:'IntechOpen is proud to announce that 191 of our authors have made the Clarivate™ Highly Cited Researchers List for 2020, ranking them among the top 1% most-cited.
\n\nThroughout the years, the list has named a total of 261 IntechOpen authors as Highly Cited. Of those researchers, 69 have been featured on the list multiple times.
\n\n\n\nReleased this past November, the list is based on data collected from the Web of Science and highlights some of the world’s most influential scientific minds by naming the researchers whose publications over the previous decade have included a high number of Highly Cited Papers placing them among the top 1% most-cited.
\n\nWe wish to congratulate all of the researchers named and especially our authors on this amazing accomplishment! We are happy and proud to share in their success!
Note: Edited in March 2021
\n'}],latestNews:[{slug:"intechopen-partners-with-ehs-for-digital-advertising-representation-20210416",title:"IntechOpen Partners with EHS for Digital Advertising Representation"},{slug:"intechopen-signs-new-contract-with-cepiec-china-for-distribution-of-open-access-books-20210319",title:"IntechOpen Signs New Contract with CEPIEC, China for Distribution of Open Access Books"},{slug:"150-million-downloads-and-counting-20210316",title:"150 Million Downloads and Counting"},{slug:"intechopen-secures-indefinite-content-preservation-with-clockss-20210309",title:"IntechOpen Secures Indefinite Content Preservation with CLOCKSS"},{slug:"intechopen-expands-to-all-global-amazon-channels-with-full-catalog-of-books-20210308",title:"IntechOpen Expands to All Global Amazon Channels with Full Catalog of Books"},{slug:"stanford-university-identifies-top-2-scientists-over-1-000-are-intechopen-authors-and-editors-20210122",title:"Stanford University Identifies Top 2% Scientists, Over 1,000 are IntechOpen Authors and Editors"},{slug:"intechopen-authors-included-in-the-highly-cited-researchers-list-for-2020-20210121",title:"IntechOpen Authors Included in the Highly Cited Researchers List for 2020"},{slug:"intechopen-maintains-position-as-the-world-s-largest-oa-book-publisher-20201218",title:"IntechOpen Maintains Position as the World’s Largest OA Book Publisher"}]},book:{item:{type:"book",id:"881",leadTitle:null,fullTitle:"Plant Pathology",title:"Plant Pathology",subtitle:null,reviewType:"peer-reviewed",abstract:"Plant pathology is an applied science that deals with the nature, causes and control of plant diseases in agriculture and forestry. The vital role of plant pathology in attaining food security and food safety for the world cannot be overemphasized.",isbn:null,printIsbn:"978-953-51-0489-6",pdfIsbn:"978-953-51-5265-1",doi:"10.5772/1390",price:139,priceEur:155,priceUsd:179,slug:"plant-pathology",numberOfPages:376,isOpenForSubmission:!1,isInWos:1,hash:"70660a5f211a94b4672ecbcb5365d2bb",bookSignature:"Christian Joseph R. Cumagun",publishedDate:"April 4th 2012",coverURL:"https://cdn.intechopen.com/books/images_new/881.jpg",numberOfDownloads:66248,numberOfWosCitations:123,numberOfCrossrefCitations:71,numberOfDimensionsCitations:143,hasAltmetrics:1,numberOfTotalCitations:337,isAvailableForWebshopOrdering:!0,dateEndFirstStepPublish:"March 15th 2011",dateEndSecondStepPublish:"April 12th 2011",dateEndThirdStepPublish:"August 17th 2011",dateEndFourthStepPublish:"September 16th 2011",dateEndFifthStepPublish:"January 14th 2012",currentStepOfPublishingProcess:5,indexedIn:"1,2,3,4,5,6",editedByType:"Edited by",kuFlag:!1,editors:[{id:"80876",title:"Dr.",name:"Christian Joseph",middleName:"Rili",surname:"Cumagun",slug:"christian-joseph-cumagun",fullName:"Christian Joseph Cumagun",profilePictureURL:"https://mts.intechopen.com/storage/users/80876/images/system/80876.jpg",biography:"Christian Joseph R. Cumagun is a professor of plant pathology at the Crop Protection Cluster, College of Agriculture, University of the Philippines Los Baños (UPLB). He obtained his BSc in Agriculture and MSc in Plant Pathology from UPLB, and his Doctorate in Agricultural Sciences (magna cum laude) from the University of Hohenheim, Germany. Dr. Cumagun received a pre-doctoral fellowship at the University of Copenhagen, Denmark and postdoctoral fellowship at Kobe University, Japan. He has published more than 30 articles in national and international peer-reviewed journals. Among his awards are: The Outstanding Young Men (TOYM) in Agricultural Sciences, from the Junior Chamber International, Philippines, and the Outstanding Young Scientist (OYS), from the National Academy of Science and Technology (NAST), Philippines. He is currently appointed a Young Affiliate of The Academy of Sciences for the Developing World (TWAS), based in Trieste, Italy.",institutionString:null,position:null,outsideEditionCount:0,totalCites:0,totalAuthoredChapters:"1",totalChapterViews:"0",totalEditedBooks:"1",institution:{name:"University of the Philippines Los Baños",institutionURL:null,country:{name:"Philippines"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,coeditorOne:null,coeditorTwo:null,coeditorThree:null,coeditorFour:null,coeditorFive:null,topics:[{id:"360",title:"Epiphytology",slug:"epiphytology"}],chapters:[{id:"34838",title:"Taxonomic Review of and Development of a Lucid Key for Philippine Cercosporoids and Related Fungi",doi:"10.5772/30214",slug:"development-of-a-lucid-key-for-philippine-cercosporoids-and-related-fungi",totalDownloads:2406,totalCrossrefCites:1,totalDimensionsCites:3,signatures:"M. Mahamuda Begum, Teresita U. Dalisay and Christian Joseph R. Cumagun",downloadPdfUrl:"/chapter/pdf-download/34838",previewPdfUrl:"/chapter/pdf-preview/34838",authors:[{id:"80876",title:"Dr.",name:"Christian Joseph",surname:"Cumagun",slug:"christian-joseph-cumagun",fullName:"Christian Joseph Cumagun"}],corrections:null},{id:"34839",title:"General Description of Rhizoctonia Species Complex",doi:"10.5772/39026",slug:"general-description-of-rhizocotonia-species-complex",totalDownloads:5688,totalCrossrefCites:15,totalDimensionsCites:25,signatures:"Genhua Yang and Chengyun Li",downloadPdfUrl:"/chapter/pdf-download/34839",previewPdfUrl:"/chapter/pdf-preview/34839",authors:[{id:"50639",title:"Prof.",name:"Chengyun",surname:"Li",slug:"chengyun-li",fullName:"Chengyun Li"},{id:"128656",title:"Prof.",name:"Yang",surname:"Genhua",slug:"yang-genhua",fullName:"Yang Genhua"}],corrections:null},{id:"34840",title:"Phytobacterial Type VI Secretion System - Gene Distribution, Phylogeny, Structure and Biological Functions",doi:"10.5772/33235",slug:"phytobacterial-type-vi-secretion-system-gene-distribution-phylogeny-structure-and-biological-functio",totalDownloads:2744,totalCrossrefCites:0,totalDimensionsCites:5,signatures:"Panagiotis F. Sarris, Emmanouil A. Trantas, Nicholas Skandalis, Anastasia P. Tampakaki, Maria Kapanidou, Michael Kokkinidis, and Nickolas J. Panopoulos",downloadPdfUrl:"/chapter/pdf-download/34840",previewPdfUrl:"/chapter/pdf-preview/34840",authors:[{id:"83916",title:"Dr.",name:"Emmanouil",surname:"Trantas",slug:"emmanouil-trantas",fullName:"Emmanouil Trantas"},{id:"92007",title:"Prof.",name:"Michael",surname:"Kokkinidis",slug:"michael-kokkinidis",fullName:"Michael Kokkinidis"},{id:"94561",title:"Prof.",name:"Nickolas",surname:"Panopoulos",slug:"nickolas-panopoulos",fullName:"Nickolas Panopoulos"},{id:"149787",title:"Dr.",name:"Panagiotis",surname:"Sarris",slug:"panagiotis-sarris",fullName:"Panagiotis Sarris"},{id:"149790",title:"Dr.",name:"Nicholas",surname:"Skandalis",slug:"nicholas-skandalis",fullName:"Nicholas Skandalis"},{id:"149791",title:"Dr.",name:"Anastasia P.",surname:"Tampakaki",slug:"anastasia-p.-tampakaki",fullName:"Anastasia P. Tampakaki"},{id:"149793",title:"Ms.",name:"Maria",surname:"Kapanidou",slug:"maria-kapanidou",fullName:"Maria Kapanidou"}],corrections:null},{id:"34841",title:"Novel Elicitors Induce Defense Responses in Cut Flowers",doi:"10.5772/30180",slug:"novel-elicitors-induce-defense-responses-in-cut-flowers",totalDownloads:2666,totalCrossrefCites:0,totalDimensionsCites:1,signatures:"Anastasios I. Darras",downloadPdfUrl:"/chapter/pdf-download/34841",previewPdfUrl:"/chapter/pdf-preview/34841",authors:[{id:"81186",title:"Dr.",name:"Anastasios",surname:"Darras",slug:"anastasios-darras",fullName:"Anastasios Darras"}],corrections:null},{id:"34842",title:"Functional Identification of Genes Encoding Effector Proteins in Magnaporthe oryzae",doi:"10.5772/39136",slug:"functional-identification-of-genes-encoding-effector-proteins-in-magnaporthe-goryzae",totalDownloads:2244,totalCrossrefCites:1,totalDimensionsCites:1,signatures:"Jing Yang and Chengyun Li",downloadPdfUrl:"/chapter/pdf-download/34842",previewPdfUrl:"/chapter/pdf-preview/34842",authors:[{id:"50639",title:"Prof.",name:"Chengyun",surname:"Li",slug:"chengyun-li",fullName:"Chengyun Li"}],corrections:null},{id:"34843",title:"The Role of the Extracellular Matrix (ECM) in Phytopathogenic Fungi: A Potential Target for Disease Control",doi:"10.5772/30801",slug:"the-role-of-the-extracellular-matrix-ecm-in-phytopathogenic-fungi-a-potential-target-for-disease-con",totalDownloads:2952,totalCrossrefCites:4,totalDimensionsCites:6,signatures:"Kenichi Ikeda, Kanako Inoue, Hiroko Kitagawa, Hiroko Meguro, Saki Shimoi and Pyoyun Park",downloadPdfUrl:"/chapter/pdf-download/34843",previewPdfUrl:"/chapter/pdf-preview/34843",authors:[{id:"84317",title:"Dr.",name:"Kenichi",surname:"Ikeda",slug:"kenichi-ikeda",fullName:"Kenichi Ikeda"}],corrections:null},{id:"34844",title:"Molecular Tools for Detection of Plant Pathogenic Fungi and Fungicide Resistance",doi:"10.5772/38011",slug:"molecular-tools-for-detection-of-plant-pathogenic-fungi-and-fungicide-resistance",totalDownloads:14671,totalCrossrefCites:35,totalDimensionsCites:60,signatures:"Nieves Capote, Ana María Pastrana, Ana Aguado and Paloma Sánchez-Torres",downloadPdfUrl:"/chapter/pdf-download/34844",previewPdfUrl:"/chapter/pdf-preview/34844",authors:[{id:"115178",title:"Dr.",name:"Nieves",surname:"Capote",slug:"nieves-capote",fullName:"Nieves Capote"},{id:"137950",title:"PhD.",name:"Ana",surname:"Aguado Puig",slug:"ana-aguado-puig",fullName:"Ana Aguado Puig"},{id:"137951",title:"Dr.",name:"Paloma",surname:"Sánchez Torres",slug:"paloma-sanchez-torres",fullName:"Paloma Sánchez Torres"}],corrections:null},{id:"34845",title:"Novel Methods for the Quantification of Pathogenic Fungi in Crop Plants: Quantitative PCR and ELISA Accurately Determine Fusarium Biomass",doi:"10.5772/30240",slug:"novel-methods-for-the-quantification-of-pathogenic-fungi-in-crop-plants-quantitative-pcr-and-elisa-a",totalDownloads:3821,totalCrossrefCites:2,totalDimensionsCites:2,signatures:"Kurt Brunner, Andreas Farnleitner and Robert L. Mach",downloadPdfUrl:"/chapter/pdf-download/34845",previewPdfUrl:"/chapter/pdf-preview/34845",authors:[{id:"81567",title:"Prof.",name:"Robert",surname:"Mach",slug:"robert-mach",fullName:"Robert Mach"},{id:"123273",title:"Dr.",name:"Kurt",surname:"Brunner",slug:"kurt-brunner",fullName:"Kurt Brunner"},{id:"123422",title:"Dr.",name:"Andreas",surname:"Farnleitner",slug:"andreas-farnleitner",fullName:"Andreas Farnleitner"}],corrections:null},{id:"34846",title:"Gray Mold of Castor: A Review",doi:"10.5772/30806",slug:"gray-mold-of-castor-bean-a-review",totalDownloads:2667,totalCrossrefCites:0,totalDimensionsCites:4,signatures:"Dartanhã José Soares",downloadPdfUrl:"/chapter/pdf-download/34846",previewPdfUrl:"/chapter/pdf-preview/34846",authors:[{id:"84334",title:"Dr.",name:"Dartanha",surname:"Soares",slug:"dartanha-soares",fullName:"Dartanha Soares"}],corrections:null},{id:"34847",title:"Effect of Nutrition and Soil Function on Pathogens of Tropical Tree Crops",doi:"10.5772/32490",slug:"effect-of-nutrition-and-soil-function-on-pathogens-of-tropical-tree-crops",totalDownloads:6909,totalCrossrefCites:3,totalDimensionsCites:7,signatures:"Peter McMahon",downloadPdfUrl:"/chapter/pdf-download/34847",previewPdfUrl:"/chapter/pdf-preview/34847",authors:[{id:"91711",title:"Dr.",name:"Peter",surname:"McMahon",slug:"peter-mcmahon",fullName:"Peter McMahon"}],corrections:null},{id:"34848",title:"Current Advances in the Fusarium Wilt Disease Management in Banana with Emphasis on Biological Control",doi:"10.5772/33775",slug:"current-advances-in-the-fusarium-wilt-disease-management-in-banana-with-emphasis-on-biological-contr",totalDownloads:8164,totalCrossrefCites:6,totalDimensionsCites:13,signatures:"R. Thangavelu and M.M. Mustaffa",downloadPdfUrl:"/chapter/pdf-download/34848",previewPdfUrl:"/chapter/pdf-preview/34848",authors:[{id:"97008",title:"Dr.",name:"Raman",surname:"Thangavelu",slug:"raman-thangavelu",fullName:"Raman Thangavelu"}],corrections:null},{id:"34849",title:"Epidemiology and Control of Plant Diseases Caused by Phytopathogenic Bacteria: The Case of Olive Knot Disease Caused by Pseudomonas savastanoi pv. savastanoi",doi:"10.5772/32544",slug:"epidemiology-and-control-of-plant-diseases-caused-by-phytopathogenic-bacteria-the-case-of-olive-knot",totalDownloads:3988,totalCrossrefCites:1,totalDimensionsCites:6,signatures:"José M. Quesada, Ramón Penyalver and María M. López",downloadPdfUrl:"/chapter/pdf-download/34849",previewPdfUrl:"/chapter/pdf-preview/34849",authors:[{id:"91879",title:"Dr.",name:"Maria Milagros",surname:"Lopez",slug:"maria-milagros-lopez",fullName:"Maria Milagros Lopez"}],corrections:null},{id:"34850",title:"Horizontal or Generalized Resistance to Pathogens in Plants",doi:"10.5772/30763",slug:"horizontal-or-generalized-resistance-to-pathogens-in-plants",totalDownloads:7332,totalCrossrefCites:3,totalDimensionsCites:10,signatures:"P.J. Keane",downloadPdfUrl:"/chapter/pdf-download/34850",previewPdfUrl:"/chapter/pdf-preview/34850",authors:[{id:"84141",title:"Dr.",name:"Philip",surname:"Keane",slug:"philip-keane",fullName:"Philip Keane"}],corrections:null}],productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"}},relatedBooks:[{type:"book",id:"1591",title:"Infrared Spectroscopy",subtitle:"Materials Science, Engineering and Technology",isOpenForSubmission:!1,hash:"99b4b7b71a8caeb693ed762b40b017f4",slug:"infrared-spectroscopy-materials-science-engineering-and-technology",bookSignature:"Theophile Theophanides",coverURL:"https://cdn.intechopen.com/books/images_new/1591.jpg",editedByType:"Edited by",editors:[{id:"37194",title:"Dr.",name:"Theophanides",surname:"Theophile",slug:"theophanides-theophile",fullName:"Theophanides Theophile"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"3161",title:"Frontiers in Guided Wave Optics and Optoelectronics",subtitle:null,isOpenForSubmission:!1,hash:"deb44e9c99f82bbce1083abea743146c",slug:"frontiers-in-guided-wave-optics-and-optoelectronics",bookSignature:"Bishnu Pal",coverURL:"https://cdn.intechopen.com/books/images_new/3161.jpg",editedByType:"Edited by",editors:[{id:"4782",title:"Prof.",name:"Bishnu",surname:"Pal",slug:"bishnu-pal",fullName:"Bishnu Pal"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"3092",title:"Anopheles mosquitoes",subtitle:"New insights into malaria vectors",isOpenForSubmission:!1,hash:"c9e622485316d5e296288bf24d2b0d64",slug:"anopheles-mosquitoes-new-insights-into-malaria-vectors",bookSignature:"Sylvie Manguin",coverURL:"https://cdn.intechopen.com/books/images_new/3092.jpg",editedByType:"Edited by",editors:[{id:"50017",title:"Prof.",name:"Sylvie",surname:"Manguin",slug:"sylvie-manguin",fullName:"Sylvie Manguin"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"371",title:"Abiotic Stress in Plants",subtitle:"Mechanisms and Adaptations",isOpenForSubmission:!1,hash:"588466f487e307619849d72389178a74",slug:"abiotic-stress-in-plants-mechanisms-and-adaptations",bookSignature:"Arun Shanker and B. Venkateswarlu",coverURL:"https://cdn.intechopen.com/books/images_new/371.jpg",editedByType:"Edited by",editors:[{id:"58592",title:"Dr.",name:"Arun",surname:"Shanker",slug:"arun-shanker",fullName:"Arun Shanker"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"72",title:"Ionic Liquids",subtitle:"Theory, Properties, New Approaches",isOpenForSubmission:!1,hash:"d94ffa3cfa10505e3b1d676d46fcd3f5",slug:"ionic-liquids-theory-properties-new-approaches",bookSignature:"Alexander Kokorin",coverURL:"https://cdn.intechopen.com/books/images_new/72.jpg",editedByType:"Edited by",editors:[{id:"19816",title:"Prof.",name:"Alexander",surname:"Kokorin",slug:"alexander-kokorin",fullName:"Alexander Kokorin"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"314",title:"Regenerative Medicine and Tissue Engineering",subtitle:"Cells and Biomaterials",isOpenForSubmission:!1,hash:"bb67e80e480c86bb8315458012d65686",slug:"regenerative-medicine-and-tissue-engineering-cells-and-biomaterials",bookSignature:"Daniel Eberli",coverURL:"https://cdn.intechopen.com/books/images_new/314.jpg",editedByType:"Edited by",editors:[{id:"6495",title:"Dr.",name:"Daniel",surname:"Eberli",slug:"daniel-eberli",fullName:"Daniel Eberli"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"57",title:"Physics and Applications of Graphene",subtitle:"Experiments",isOpenForSubmission:!1,hash:"0e6622a71cf4f02f45bfdd5691e1189a",slug:"physics-and-applications-of-graphene-experiments",bookSignature:"Sergey Mikhailov",coverURL:"https://cdn.intechopen.com/books/images_new/57.jpg",editedByType:"Edited by",editors:[{id:"16042",title:"Dr.",name:"Sergey",surname:"Mikhailov",slug:"sergey-mikhailov",fullName:"Sergey Mikhailov"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"1373",title:"Ionic Liquids",subtitle:"Applications and Perspectives",isOpenForSubmission:!1,hash:"5e9ae5ae9167cde4b344e499a792c41c",slug:"ionic-liquids-applications-and-perspectives",bookSignature:"Alexander Kokorin",coverURL:"https://cdn.intechopen.com/books/images_new/1373.jpg",editedByType:"Edited by",editors:[{id:"19816",title:"Prof.",name:"Alexander",surname:"Kokorin",slug:"alexander-kokorin",fullName:"Alexander Kokorin"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"2270",title:"Fourier Transform",subtitle:"Materials Analysis",isOpenForSubmission:!1,hash:"5e094b066da527193e878e160b4772af",slug:"fourier-transform-materials-analysis",bookSignature:"Salih Mohammed Salih",coverURL:"https://cdn.intechopen.com/books/images_new/2270.jpg",editedByType:"Edited by",editors:[{id:"111691",title:"Dr.Ing.",name:"Salih",surname:"Salih",slug:"salih-salih",fullName:"Salih Salih"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"872",title:"Organic Pollutants Ten Years After the Stockholm Convention",subtitle:"Environmental and Analytical Update",isOpenForSubmission:!1,hash:"f01dc7077e1d23f3d8f5454985cafa0a",slug:"organic-pollutants-ten-years-after-the-stockholm-convention-environmental-and-analytical-update",bookSignature:"Tomasz Puzyn and Aleksandra Mostrag-Szlichtyng",coverURL:"https://cdn.intechopen.com/books/images_new/872.jpg",editedByType:"Edited by",editors:[{id:"84887",title:"Dr.",name:"Tomasz",surname:"Puzyn",slug:"tomasz-puzyn",fullName:"Tomasz Puzyn"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}],ofsBooks:[]},correction:{item:{id:"71744",slug:"corrigendum-to-technical-advances-in-chloroplast-biotechnology",title:"Corrigendum to: Technical Advances in Chloroplast Biotechnology",doi:null,correctionPDFUrl:"https://cdn.intechopen.com/pdfs/71744.pdf",downloadPdfUrl:"/chapter/pdf-download/71744",previewPdfUrl:"/chapter/pdf-preview/71744",totalDownloads:null,totalCrossrefCites:null,bibtexUrl:"/chapter/bibtex/71744",risUrl:"/chapter/ris/71744",chapter:{id:"65358",slug:"technical-advances-in-chloroplast-biotechnology",signatures:"Muhammad Sarwar Khan, Ghulam Mustafa and Faiz Ahmad Joyia",dateSubmitted:"June 12th 2018",dateReviewed:"August 31st 2018",datePrePublished:"January 25th 2019",datePublished:"October 23rd 2019",book:{id:"6976",title:"Transgenic Crops",subtitle:"Emerging Trends and Future Perspectives",fullTitle:"Transgenic Crops - Emerging Trends and Future Perspectives",slug:"transgenic-crops-emerging-trends-and-future-perspectives",publishedDate:"October 23rd 2019",bookSignature:"Muhammad Sarwar Khan and Kauser Abdulla Malik",coverURL:"https://cdn.intechopen.com/books/images_new/6976.jpg",licenceType:"CC BY 3.0",editedByType:"Edited by",editors:[{id:"212511",title:"Prof.",name:"Muhammad Sarwar",middleName:null,surname:"Khan",slug:"muhammad-sarwar-khan",fullName:"Muhammad Sarwar Khan"}],productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"}},authors:[{id:"211046",title:"Dr.",name:"Ghulam",middleName:null,surname:"Mustafa",fullName:"Ghulam Mustafa",slug:"ghulam-mustafa",email:"drmustafa8@gmail.com",position:null,institution:{name:"University of Agriculture Faisalabad",institutionURL:null,country:{name:"Pakistan"}}},{id:"212508",title:"Dr.",name:"Faiz",middleName:null,surname:"Ahmad",fullName:"Faiz Ahmad",slug:"faiz-ahmad",email:"faizahmad1980@gmail.com",position:null,institution:null},{id:"212511",title:"Prof.",name:"Muhammad Sarwar",middleName:null,surname:"Khan",fullName:"Muhammad Sarwar Khan",slug:"muhammad-sarwar-khan",email:"sarwarkhan_40@hotmail.com",position:null,institution:{name:"University of Agriculture Faisalabad",institutionURL:null,country:{name:"Pakistan"}}}]}},chapter:{id:"65358",slug:"technical-advances-in-chloroplast-biotechnology",signatures:"Muhammad Sarwar Khan, Ghulam Mustafa and Faiz Ahmad Joyia",dateSubmitted:"June 12th 2018",dateReviewed:"August 31st 2018",datePrePublished:"January 25th 2019",datePublished:"October 23rd 2019",book:{id:"6976",title:"Transgenic Crops",subtitle:"Emerging Trends and Future Perspectives",fullTitle:"Transgenic Crops - Emerging Trends and Future Perspectives",slug:"transgenic-crops-emerging-trends-and-future-perspectives",publishedDate:"October 23rd 2019",bookSignature:"Muhammad Sarwar Khan and Kauser Abdulla Malik",coverURL:"https://cdn.intechopen.com/books/images_new/6976.jpg",licenceType:"CC BY 3.0",editedByType:"Edited by",editors:[{id:"212511",title:"Prof.",name:"Muhammad Sarwar",middleName:null,surname:"Khan",slug:"muhammad-sarwar-khan",fullName:"Muhammad Sarwar Khan"}],productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"}},authors:[{id:"211046",title:"Dr.",name:"Ghulam",middleName:null,surname:"Mustafa",fullName:"Ghulam Mustafa",slug:"ghulam-mustafa",email:"drmustafa8@gmail.com",position:null,institution:{name:"University of Agriculture Faisalabad",institutionURL:null,country:{name:"Pakistan"}}},{id:"212508",title:"Dr.",name:"Faiz",middleName:null,surname:"Ahmad",fullName:"Faiz Ahmad",slug:"faiz-ahmad",email:"faizahmad1980@gmail.com",position:null,institution:null},{id:"212511",title:"Prof.",name:"Muhammad Sarwar",middleName:null,surname:"Khan",fullName:"Muhammad Sarwar Khan",slug:"muhammad-sarwar-khan",email:"sarwarkhan_40@hotmail.com",position:null,institution:{name:"University of Agriculture Faisalabad",institutionURL:null,country:{name:"Pakistan"}}}]},book:{id:"6976",title:"Transgenic Crops",subtitle:"Emerging Trends and Future Perspectives",fullTitle:"Transgenic Crops - Emerging Trends and Future Perspectives",slug:"transgenic-crops-emerging-trends-and-future-perspectives",publishedDate:"October 23rd 2019",bookSignature:"Muhammad Sarwar Khan and Kauser Abdulla Malik",coverURL:"https://cdn.intechopen.com/books/images_new/6976.jpg",licenceType:"CC BY 3.0",editedByType:"Edited by",editors:[{id:"212511",title:"Prof.",name:"Muhammad Sarwar",middleName:null,surname:"Khan",slug:"muhammad-sarwar-khan",fullName:"Muhammad Sarwar Khan"}],productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"}}},ofsBook:{item:{type:"book",id:"1966",leadTitle:null,title:"Molecular Dynamics",subtitle:"Theoretical Developments and Applications in Nanotechnology and Energy",reviewType:"peer-reviewed",abstract:"Molecular Dynamics is a two-volume compendium of the ever-growing applications of molecular dynamics simulations to solve a wider range of scientific and engineering challenges. The contents illustrate the rapid progress on molecular dynamics simulations in many fields of science and technology, such as nanotechnology, energy research, and biology, due to the advances of new dynamics theories and the extraordinary power of today's computers. \nThis first book begins with a general description of underlying theories of molecular dynamics simulations and provides extensive coverage of molecular dynamics simulations in nanotechnology and energy. \n\nCoverage of this book includes:\n\nRecent advances of molecular dynamics theory \nFormation and evolution of nanoparticles of up to 106 atoms\nDiffusion and dissociation of gas and liquid molecules on silicon, metal, or \n metal organic frameworks\nConductivity of ionic species in solid oxides \nIon solvation in liquid mixtures\nNuclear structures",isbn:null,printIsbn:"978-953-51-0443-8",pdfIsbn:"978-953-51-4306-2",doi:"10.5772/2383",price:139,priceEur:155,priceUsd:179,slug:"molecular-dynamics-theoretical-developments-and-applications-in-nanotechnology-and-energy",numberOfPages:438,isOpenForSubmission:!1,hash:"c1e56574dff3c36a222df9d90ccebf9c",bookSignature:"Lichang Wang",publishedDate:"April 5th 2012",coverURL:"https://cdn.intechopen.com/books/images_new/1966.jpg",keywords:null,numberOfDownloads:48002,numberOfWosCitations:54,numberOfCrossrefCitations:22,numberOfDimensionsCitations:41,numberOfTotalCitations:117,isAvailableForWebshopOrdering:!0,dateEndFirstStepPublish:"May 5th 2011",dateEndSecondStepPublish:"June 2nd 2011",dateEndThirdStepPublish:"October 7th 2011",dateEndFourthStepPublish:"November 6th 2011",dateEndFifthStepPublish:"March 5th 2012",remainingDaysToSecondStep:"10 years",secondStepPassed:!0,currentStepOfPublishingProcess:5,editedByType:"Edited by",kuFlag:!1,biosketch:null,coeditorOneBiosketch:null,coeditorTwoBiosketch:null,coeditorThreeBiosketch:null,coeditorFourBiosketch:null,coeditorFiveBiosketch:null,editors:[{id:"107906",title:"Prof.",name:"Lichang",middleName:null,surname:"Wang",slug:"lichang-wang",fullName:"Lichang Wang",profilePictureURL:"https://mts.intechopen.com/storage/users/107906/images/2339_n.jpg",biography:"Lichang Wang, Ph.D., is Professor of Chemistry and Biochemistry at Southern Illinois University Carbondale and the founder and president of MASIS, Inc. Her research activities encompass the area of molecular modeling, such as developing molecular dynamics simulation tools for complex systems and performing dynamics simulations and electronic structure calculations to study various systems of chemical and energy interests: (a) Transition metal nanoparticles, their toxicity to humans, and their catalytic activities for dehydrogenation of CH4, reduction of O2, direct conversion of coal to liquid fuel, and reactions of ethanol; and (b) Organic dyes for solar cell applications. Details of her research can be found on the website: http://www.chem.siu.edu/wang. The ultimate goal of her research activities is to replace as many bench top R & D experiments as possible by molecular modeling in order to achieve a greener, as well as economically better, R & D in Chemical and Energy Industries.",institutionString:null,position:null,outsideEditionCount:0,totalCites:0,totalAuthoredChapters:"1",totalChapterViews:"0",totalEditedBooks:"2",institution:{name:"Southern Illinois University Carbondale",institutionURL:null,country:{name:"United States of America"}}}],coeditorOne:null,coeditorTwo:null,coeditorThree:null,coeditorFour:null,coeditorFive:null,topics:[{id:"970",title:"Mathematical Physics",slug:"mathematical-physics"}],chapters:[{id:"34975",title:"Recent Advances in Fragment Molecular Orbital-Based Molecular Dynamics (FMO-MD) Simulations",slug:"recent-advances-in-fragment-molecular-orbital-based-molecular-dynamics-fmo-md-simulations",totalDownloads:3010,totalCrossrefCites:10,authors:[{id:"103606",title:"Dr.",name:"Yuto",surname:"Komeiji",slug:"yuto-komeiji",fullName:"Yuto Komeiji"}]},{id:"34976",title:"Advanced Molecular Dynamics Simulations on the Formation of Transition Metal Nanoparticles",slug:"advanced-molecular-dynamics-simulations-on-the-formation-of-transition-metal-nanoparticles",totalDownloads:3147,totalCrossrefCites:1,authors:[{id:"107906",title:"Prof.",name:"Lichang",surname:"Wang",slug:"lichang-wang",fullName:"Lichang Wang"}]},{id:"34977",title:"Numerical Integration Techniques Based on a Geometric View and Application to Molecular Dynamics Simulations",slug:"numerical-integration-techniques-based-on-a-geometric-view-in-molecular-dynamics-simulations",totalDownloads:1567,totalCrossrefCites:0,authors:[{id:"112067",title:"Dr.",name:"Ikuo",surname:"Fukuda",slug:"ikuo-fukuda",fullName:"Ikuo Fukuda"}]},{id:"34978",title:"Application of Molecular Dynamics Simulation to Small Systems",slug:"application-of-molecular-dynamics-simulations-to-small-systems",totalDownloads:3356,totalCrossrefCites:0,authors:[{id:"105687",title:"Prof.",name:"Victor M.",surname:"Rosas-Garcia",slug:"victor-m.-rosas-garcia",fullName:"Victor M. Rosas-Garcia"},{id:"136475",title:"Prof.",name:"Isabel",surname:"Sáenz-Tavera",slug:"isabel-saenz-tavera",fullName:"Isabel Sáenz-Tavera"}]},{id:"34979",title:"Molecular Dynamics Simulations and Thermal Transport at the Nano-Scale",slug:"molecular-dynamics-simulations-and-thermal-transport-at-the-nano-scale",totalDownloads:4149,totalCrossrefCites:4,authors:[{id:"110506",title:"Dr.",name:"Konstantinos",surname:"Termentzidis",slug:"konstantinos-termentzidis",fullName:"Konstantinos Termentzidis"},{id:"116542",title:"Dr.",name:"Samy",surname:"Merabia",slug:"samy-merabia",fullName:"Samy Merabia"}]},{id:"34980",title:"Developing a Systematic Approach for Ab Initio Path-Integral Simulations",slug:"developing-a-systematic-approach-for-ab-initio-path-integral-simulations",totalDownloads:2588,totalCrossrefCites:0,authors:[{id:"102586",title:"Dr.",name:"Kin-Yiu",surname:"Wong",slug:"kin-yiu-wong",fullName:"Kin-Yiu Wong"}]},{id:"34981",title:"Antisymmetrized Molecular Dynamics and Nuclear Structure",slug:"antisymmetrized-molecular-dynamics-and-nuclear-structure",totalDownloads:1654,totalCrossrefCites:0,authors:[{id:"102412",title:"Prof.",name:"Gaotsiwe",surname:"Rampho",slug:"gaotsiwe-rampho",fullName:"Gaotsiwe Rampho"}]},{id:"34982",title:"Antisymmetrized Molecular Dynamics with Bare Nuclear Interactions: Brueckner-AMD, and Its Applications to Light Nuclei",slug:"antisymmetrized-molecular-dynamics-with-bare-nuclear-interactions-brueckner-amd-and-its-applications",totalDownloads:1742,totalCrossrefCites:0,authors:[{id:"108597",title:"Dr.",name:"Tomoaki",surname:"Togashi",slug:"tomoaki-togashi",fullName:"Tomoaki Togashi"}]},{id:"34983",title:"Formation and Evolution Characteristics of Nano-Clusters (For Large-Scale Systems of 106 Liquid Metal Atoms)",slug:"formation-and-evolution-characteristics-of-nano-clusters",totalDownloads:1750,totalCrossrefCites:1,authors:[{id:"102488",title:"Prof.",name:"Rang-Su",surname:"Liu",slug:"rang-su-liu",fullName:"Rang-Su Liu"}]},{id:"34984",title:"A Molecular Dynamics Study on Au",slug:"a-molecular-dynamics-study-on-au",totalDownloads:1788,totalCrossrefCites:0,authors:[{id:"105733",title:"Dr.",name:"Yasemin",surname:"Ciftci",slug:"yasemin-ciftci",fullName:"Yasemin Ciftci"}]},{id:"34985",title:"Gelation of Magnetic Nanoparticles",slug:"gelation-of-magnetic-nanoparticles",totalDownloads:2520,totalCrossrefCites:2,authors:[{id:"107277",title:"Dr.",name:"Eldin Wee Chuan",surname:"Lim",slug:"eldin-wee-chuan-lim",fullName:"Eldin Wee Chuan Lim"}]},{id:"34986",title:"Inelastic Collisions and Hypervelocity Impacts at Nanoscopic Level: A Molecular Dynamics Study",slug:"inelastic-collisions-and-hypervelocity-impacts-at-nanoscopic-level-a-molecular-dynamics-study-",totalDownloads:2466,totalCrossrefCites:1,authors:[{id:"113037",title:"Prof.",name:"Gonzalo",surname:"Gutierrez",slug:"gonzalo-gutierrez",fullName:"Gonzalo Gutierrez"},{id:"114312",title:"Dr.",name:"Sergio",surname:"Davis",slug:"sergio-davis",fullName:"Sergio Davis"},{id:"114315",title:"Dr.",name:"Claudia",surname:"Loyola",slug:"claudia-loyola",fullName:"Claudia Loyola"},{id:"114316",title:"Ph.D.",name:"Felipe",surname:"González-Cataldo",slug:"felipe-gonzalez-cataldo",fullName:"Felipe González-Cataldo"},{id:"114317",title:"Mrs.",name:"Yasmin",surname:"Navarrete",slug:"yasmin-navarrete",fullName:"Yasmin Navarrete"},{id:"114319",title:"Mr.",name:"Felipe",surname:"Gonzalez-Wasaff",slug:"felipe-gonzalez-wasaff",fullName:"Felipe Gonzalez-Wasaff"},{id:"147102",title:"Dr.",name:"Joaquin",surname:"Peralta",slug:"joaquin-peralta",fullName:"Joaquin Peralta"}]},{id:"34987",title:"Recent Advances in Molecular Dynamics Simulations of Gas Diffusion in Metal Organic Frameworks",slug:"recent-advances-in-molecular-dynamics-simulations-of-gas-diffusion-in-metal-organic-frameworks",totalDownloads:3437,totalCrossrefCites:1,authors:[{id:"106387",title:"Prof.",name:"Seda",surname:"Keskin",slug:"seda-keskin",fullName:"Seda Keskin"}]},{id:"34988",title:"Molecular Dynamic Simulation of Short Order and Hydrogen Diffusion in the Disordered Metal Systems",slug:"molecular-dynamic-research-of-short-order-and-hydrogen-diffusion-in-the-disordered-metal-systems",totalDownloads:2942,totalCrossrefCites:0,authors:[{id:"111988",title:"Dr.",name:"Victor",surname:"Chentsov",slug:"victor-chentsov",fullName:"Victor Chentsov"},{id:"112518",title:"Dr.",name:"Eduard",surname:"Pastukhov",slug:"eduard-pastukhov",fullName:"Eduard Pastukhov"},{id:"112547",title:"Dr.",name:"Nicolay",surname:"Sidorov",slug:"nicolay-sidorov",fullName:"Nicolay Sidorov"},{id:"112548",title:"Dr.",name:"Andrej",surname:"Vostrjakov",slug:"andrej-vostrjakov",fullName:"Andrej Vostrjakov"}]},{id:"34989",title:"Molecular Simulation of Dissociation Phenomena of Gas Molecule on Metal Surface",slug:"molecular-simulation-of-dissociation-phenomena-of-gas-molecule-on-metal-surface",totalDownloads:2123,totalCrossrefCites:0,authors:[{id:"105187",title:"Dr.",name:"Takashi",surname:"Tokumasu",slug:"takashi-tokumasu",fullName:"Takashi Tokumasu"}]},{id:"34990",title:"A Study of the Adsorption and Diffusion Behavior of a Single Polydimethylsiloxane Chain on a Silicon Surface by Molecular Dynamics Simulation",slug:"a-study-of-the-adsorption-and-diffusion-behavior-of-a-single-polydimethylsiloxane-chain-on-a-silicon",totalDownloads:1846,totalCrossrefCites:0,authors:[{id:"105602",title:"Prof.",name:"Dan",surname:"Mu",slug:"dan-mu",fullName:"Dan Mu"},{id:"105603",title:"Mr.",name:"Jian-Quan",surname:"Li",slug:"jian-quan-li",fullName:"Jian-Quan Li"}]},{id:"34991",title:"The Roles of Classical Molecular Dynamics Simulation in Solid Oxide Fuel Cells",slug:"molecular-dynamics-for-solid-oxide-fuel-cells",totalDownloads:2679,totalCrossrefCites:0,authors:[{id:"104044",title:"Dr.",name:"Kah Chun",surname:"Lau",slug:"kah-chun-lau",fullName:"Kah Chun Lau"},{id:"111870",title:"Dr.",name:"Brett. I",surname:"Dunlap",slug:"brett.-i-dunlap",fullName:"Brett. I Dunlap"}]},{id:"34992",title:"Molecular Dynamics Simulation and Conductivity Mechanism in Fast Ionic Crystals Based on Hollandite NaxCrxTi8-xO16",slug:"molecular-dynamics-simulation-and-conductivity-mechanism-in-fast-ionic-crystals-based-on-hollandite-",totalDownloads:2523,totalCrossrefCites:1,authors:[{id:"110583",title:"Dr.",name:"Kien Ling",surname:"Khoo",slug:"kien-ling-khoo",fullName:"Kien Ling Khoo"}]},{id:"34993",title:"MD Simulation of the Ion Solvation in Methanol-Water Mixtures",slug:"md-simulation-of-the-ion-3-solvation-in-methanol-water-mixtures",totalDownloads:2718,totalCrossrefCites:1,authors:[{id:"106391",title:"Prof.",name:"Ewa",surname:"Hawlicka",slug:"ewa-hawlicka",fullName:"Ewa Hawlicka"}]}],productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"},personalPublishingAssistant:{id:"97745",firstName:"Daria",lastName:"Nahtigal",middleName:null,title:"Ms.",imageUrl:"https://mts.intechopen.com/storage/users/97745/images/2231_n.png",email:"nahtigal@intechopen.com",biography:"Editor Relations Consultant at InTech\n- organize workflow within the assigned projects and editors\n- pursue an active and efficient editor acquisitions policy through correspondence, meetings, trips, telephone, consultations with advisors\n- sign new products per annual signing goals\n- handle editors and their projects through close communication, manage editorial schedules and monitor production stages\n- handle members of scientific and editorial boards and assign them to related projects \n- negotiate contract terms and conditions of editor initiated book projects\n- manage expanded editor projects (conference attendance, conference supporting material, promotion of editor’s projects, etc.)\n- build and maintain industry knowledge and relationships by means of editor/industry contacts, conference attendance to propose new ways of cooperation and professional training\n- communicate product/editor benefits to marketing\n- participate in planning, execution and attendance of conferences\n- liaison with marketing and publishing personnel to optimise programme results\n- research and identify book topics or editor projects with strong sales potential and recruit experienced and competent editors, recognize potential new editors and cultivate working relationships with them, obtain proposals from potential editors, determine the quality of the proposals, find and liaise with reviewers/editors\n- related duties as required"}},relatedBooks:[{type:"book",id:"2265",title:"Molecular Dynamics",subtitle:"Studies of Synthetic and Biological Macromolecules",isOpenForSubmission:!1,hash:"58aa18b5670a4dcc031fe3d9006767aa",slug:"molecular-dynamics-studies-of-synthetic-and-biological-macromolecules",bookSignature:"Lichang Wang",coverURL:"https://cdn.intechopen.com/books/images_new/2265.jpg",editedByType:"Edited by",editors:[{id:"107906",title:"Prof.",name:"Lichang",surname:"Wang",slug:"lichang-wang",fullName:"Lichang Wang"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"5192",title:"Nonlinear Systems",subtitle:"Design, Analysis, Estimation and Control",isOpenForSubmission:!1,hash:"f0fcb297b36945433902e923bf668b8b",slug:"nonlinear-systems-design-analysis-estimation-and-control",bookSignature:"Dongbin Lee, Tim Burg and Christos Volos",coverURL:"https://cdn.intechopen.com/books/images_new/5192.jpg",editedByType:"Edited by",editors:[{id:"147032",title:"Prof.",name:"Dongbin",surname:"Lee",slug:"dongbin-lee",fullName:"Dongbin Lee"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"6128",title:"Resonance",subtitle:null,isOpenForSubmission:!1,hash:"da5cccb1323ad52317e2001caf4e92f9",slug:"resonance",bookSignature:"Jan Awrejcewicz",coverURL:"https://cdn.intechopen.com/books/images_new/6128.jpg",editedByType:"Edited by",editors:[{id:"68338",title:"Prof.",name:"Jan",surname:"Awrejcewicz",slug:"jan-awrejcewicz",fullName:"Jan Awrejcewicz"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"8345",title:"Boundary Layer Flows",subtitle:"Theory, Applications and Numerical Methods",isOpenForSubmission:!1,hash:"14d9725e87983a03938f073f6c5ee815",slug:"boundary-layer-flows-theory-applications-and-numerical-methods",bookSignature:"Vallampati Ramachandra Prasad",coverURL:"https://cdn.intechopen.com/books/images_new/8345.jpg",editedByType:"Edited by",editors:[{id:"146601",title:"Dr.",name:"Vallampati",surname:"Ramachandra Prasad",slug:"vallampati-ramachandra-prasad",fullName:"Vallampati Ramachandra Prasad"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"6716",title:"Perturbation Methods with Applications in Science and Engineering",subtitle:null,isOpenForSubmission:!1,hash:"4eb95b646172fe61a2068c4a98ac13e4",slug:"perturbation-methods-with-applications-in-science-and-engineering",bookSignature:"İlkay Bakırtaş",coverURL:"https://cdn.intechopen.com/books/images_new/6716.jpg",editedByType:"Edited by",editors:[{id:"186388",title:"Prof.",name:"İlkay",surname:"Bakırtaş",slug:"ilkay-bakirtas",fullName:"İlkay Bakırtaş"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"1591",title:"Infrared Spectroscopy",subtitle:"Materials Science, Engineering and Technology",isOpenForSubmission:!1,hash:"99b4b7b71a8caeb693ed762b40b017f4",slug:"infrared-spectroscopy-materials-science-engineering-and-technology",bookSignature:"Theophile Theophanides",coverURL:"https://cdn.intechopen.com/books/images_new/1591.jpg",editedByType:"Edited by",editors:[{id:"37194",title:"Dr.",name:"Theophanides",surname:"Theophile",slug:"theophanides-theophile",fullName:"Theophanides Theophile"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"3161",title:"Frontiers in Guided Wave Optics and Optoelectronics",subtitle:null,isOpenForSubmission:!1,hash:"deb44e9c99f82bbce1083abea743146c",slug:"frontiers-in-guided-wave-optics-and-optoelectronics",bookSignature:"Bishnu Pal",coverURL:"https://cdn.intechopen.com/books/images_new/3161.jpg",editedByType:"Edited by",editors:[{id:"4782",title:"Prof.",name:"Bishnu",surname:"Pal",slug:"bishnu-pal",fullName:"Bishnu Pal"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"3092",title:"Anopheles mosquitoes",subtitle:"New insights into malaria vectors",isOpenForSubmission:!1,hash:"c9e622485316d5e296288bf24d2b0d64",slug:"anopheles-mosquitoes-new-insights-into-malaria-vectors",bookSignature:"Sylvie Manguin",coverURL:"https://cdn.intechopen.com/books/images_new/3092.jpg",editedByType:"Edited by",editors:[{id:"50017",title:"Prof.",name:"Sylvie",surname:"Manguin",slug:"sylvie-manguin",fullName:"Sylvie Manguin"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"371",title:"Abiotic Stress in Plants",subtitle:"Mechanisms and Adaptations",isOpenForSubmission:!1,hash:"588466f487e307619849d72389178a74",slug:"abiotic-stress-in-plants-mechanisms-and-adaptations",bookSignature:"Arun Shanker and B. Venkateswarlu",coverURL:"https://cdn.intechopen.com/books/images_new/371.jpg",editedByType:"Edited by",editors:[{id:"58592",title:"Dr.",name:"Arun",surname:"Shanker",slug:"arun-shanker",fullName:"Arun Shanker"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"72",title:"Ionic Liquids",subtitle:"Theory, Properties, New Approaches",isOpenForSubmission:!1,hash:"d94ffa3cfa10505e3b1d676d46fcd3f5",slug:"ionic-liquids-theory-properties-new-approaches",bookSignature:"Alexander Kokorin",coverURL:"https://cdn.intechopen.com/books/images_new/72.jpg",editedByType:"Edited by",editors:[{id:"19816",title:"Prof.",name:"Alexander",surname:"Kokorin",slug:"alexander-kokorin",fullName:"Alexander Kokorin"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}]},chapter:{item:{type:"chapter",id:"73490",title:"The Analytic Functional Resonance Analysis to Improve Safety Management",doi:"10.5772/intechopen.93998",slug:"the-analytic-functional-resonance-analysis-to-improve-safety-management",body:'\nAlthough over the years, industrial plants have improved their safety management processes, it is evident that safety systems need to be further improved [1]. This need is underlined by the many accidents that have occurred in industrial plants over recent years, arising from human causes, technical causes, or natural causes. Traditional safety management models are designed to identify negative factors and develop systems to mitigate their impact. These models allow to analyze different critical situations, but they seem ineffective for today’s business needs [2]. Particularly, in modern industrial plants, only a few functions are independent of each other. Thus, analyzing them individually may not be the best model. In general, due to the complexity of the systems it is necessary to analyze all functions and tasks. In this perspective, Resilience Engineering (RE) is a useful approach to manage complex systems. This approach is a new way to think about safety and risk management [3]. Unlike the classic risk management approaches that are based on the analysis of a posteriori causes by adopting a linear cause-and-effect approach, the RE adopts a perspective that refers to the theory of complexity. RE aims to revise the analysis models to create processes that are flexible and robust. Functional Resonance Analysis Method (FRAM) proposed by Hollnagel defines complex systems through their functions and studies the interactions between these functions [4]. The main
Thus, in the present research the FRAM method is used in conjunction with Analytic Hierarchy Process (AHP) to overcome the limits of the FRAM. AHP is a well-known multi-criteria decision support technique developed in the 1970s by the Prof. Thomas L. Saaty [5]. The proposed model overcomes the qualitative limits of the resilience engineering models proposed in the literature. The AHP helps to assess the subjective probability of an event or trigger cause. Furthermore, through the integration of the AHP it allows to evaluate the strength of relationship between the variability of human performance and influence of the external environment. The preset study is a pilot research. The proposed process will be tested in other situations and industrial settings. In fact, the model is extremely flexible and can be applied in different scenario.
\nThe rest of the paper is organized as follows. Section 2 presents a general overview on resilience engineering approach and a brief state of art. Section 3 describes the proposed model based on FRAM and AHP. Section 4 describes a real case study in a petrochemical industry and its results. Finally, in Section 5 conclusion of the proposed “model” and the future research are summarized.
\nResilience Engineering (RE) is a multidisciplinary field of study dealing with safety in complex systems that have several interdependent elements from an economic, human, and social point of view [6]. RE is the intrinsic ability of a system to modify its functioning before, during and following a change or disruption, in order to be able to continue the necessary operations both under foreseen and unforeseen conditions [7]. In general, safety is defined as a condition that minimizes the number of negative outcomes. Thus, it is possible to understand the functioning of a system by analyzing its parts. Therefore, in this view the aim is to reduce the number of accidents by reducing their causes. This is the so-called
Documents by year.
A country where there is greater scientific interest is Italy (27,6%), followed by Brazil (17%), as it is shown in Figure 2. The publications are mostly articles published in international journals (63,8%) and conference paper (31,9%). Furthermore, the survey pointed out that most of the research is in the engineering area (36,3%) as shown in Figure 3.
\nDocuments by country.
Documents by subject area.
A recent study developed by Patriarca et al. [13] highlighted that aviation is by far the most investigated domain with the FRAM with a percentage equal to 24,87%. This is not a surprising result since FRAM was developed in the aeronautical field. Other emerging sectors are healthcare (13,99%) and industrial operations (12,44%) as demonstrated by several publications [14, 15, 16]. Furthermore, some authors pointed out that FRAM does not assess the human behavior and the human performance to analyze the human error [17, 18].
\nOther publications demonstrated how FRAM is a qualitative approach for accident, risk and system analysis and it does not support quantification [19, 20, 21]. Definitely, FRAM is a qualitative method. Furthermore, it does not support quantification. To overcome this issue, FRAM is used together with the Analytic Hierarchy Process (AHP). Thus, it is possible to measure the subjectivity in establishing the potential variability of functions as suggested by Rosa et al. [22]. The integration of FRAM-AHP is proposed also in other two works. Both applied the hybrid to evaluate construction sustainability [23, 24].
\nFRAM methodology aims to analyze how the variability of one or more functions can be combined between them and how to prevent their resonance, which could lead to unwanted results [25]. For this purpose, FRAM method studies the system first under normal conditions, after FRAM analyzes the variability that cause to the event unwanted. The aim is obviously to be able to issue recommendations that prevent the repetition of the event. FRAM consists of four steps: 1) Identify system functions; 2) Characterize the potential variability of the functions; 4) Determine the dependencies among functions and 4) Monitor the variability. Some more details about each step are provided below [26].
\nFRAM hexagon: The six aspects used to characterize functions.
Output variability of upstream function | \nPossible effects on downstream function | \n|
---|---|---|
Time | \nToo early | \nFalse start (V+) | \n
Possible damping (V-) | \n||
In time | \nPossible damping (V-) | \n|
Too late | \nDelayed activities (V+) | \n|
Omission | \nStart imprecision (V+) | \n|
Accuracy | \nInaccurate | \nWaste of time (V+) | \n
Acceptable | \nNo change (V=) | \n|
Accurate | \nPossible damping (V-) | \n
Example of aggregation of functions (output – input).
The main feature of Analytic Hierarchy Process (AHP) is to break down a decision-making problem in a hierarchy [31]. AHP uses a mathematical approach based on matrix algebra to “measure” decisions [32]. AHP is characterized by three main phases as described below.
\nSummary of the main steps and phases of the study.
The model was applied in a real case study concerning the management of an emergency in a petrochemical company (see Figure 6). The plant consists of process and service plants. Plant processes include: Predistillation unit; Propane unit; Distillation unit; Catalytic hydrogenation unit and Diesel oil purification. While service facilities include: Diathermic oil system; Steam and hot water production unit; Refinery torch; Hydrogen production unit; Cooling water system and Refinery storage area. The plant preserves extremely dangerous substances in quantities equal to or greater than the limits. Thus, it is a plant with a high risk activity, where it is necessary to analyze all the deviations from the operating standards (emergency conditions) such as: gas leakage, hydrocarbon release, fire, earthquake, flood, sabotage, pollution, etc.
\nPetrochemical plant.
# | \nOperations | \nResponsible | \n
---|---|---|
1 | \nActivate Electrostatic discharge (ESD) control from the control room to stop the transfer and close the cut-off valves | \nDesk operator | \n
2 | \nActivate the shower cooling system on the truck through the 10HC1V system | \nDesk operator | \n
3 | \nIf possible, intercept the ATB side valve | \nTruck driver | \n
4 | \nDisconnect the unloading arms | \nInternal operator | \n
5 | \nTurn away truck | \nInternal operator | \n
6 | \nAlternatively, continue the unloading operations until the tanker is emptied, and the gas is depressurized | \nInternal operator | \n
7 | \nActivate hydro-foam cannon | \nInternal operator | \n
8 | \nTurn off furnace and cool surrounding equipment | \nInternal operator | \n
Functions of the system.
\nFigure 7 shows the FRAM of the emergency management activity. FRAM Model Visualiser (FMV) was used to create a graphical representation of a FRAM model ((https://functionalresonance.com/FMV/index.html).
\nFRAM representation of the system.
According to the analysis, the
PSF#1 Training and Experience. It refers to the experience and training of the operator(s) involved in the task.
PSF#2 Procedures and Administrative Controls. It refers to the existence and use of formal operating procedures.
PSF#3 Ergonomics and Human Machine Interaction. It refers to the adequacy or inadequacy of machine (i.e. computer).
PSF#4 Time Available. It refers to the adequacy or inadequacy of the time available to complete a task.
PSF#5 Complexity. It refers to the difficult of the task to perform (simple, easy, difficult, very difficult, difficult beyond standards).
PSF#6 Workload, Stress and Stressors. It refers to mental stress or excessive workload.
PSF#7 Work Processes. It refers to the adequacy or inadequacy of safety culture, management policies/support, etc.
AHP model.
\nTable 3 summarized the weights of variability in which operators are involved according to PSFs. The weights of the factors are defined through AHP. More specifically, it emerges that PSF#1, PSF#4 and PSF#6 present a higher probability of occurrence.
\nPSFs | \nWeighting of variability | \n
---|---|
PSF#1 | \n0,29,448 | \n
PSF#2 | \n0,14,892 | \n
PSF#3 | \n0,04571 | \n
PSF#4 | \n0,15,991 | \n
PSF#5 | \n0,10,006 | \n
PSF#6 | \n0,18,167 | \n
PSF#7 | \n0,06925 | \n
Weighting of output variability.
A graphic representation of Table 3 is shown in Figure 9.
\nProbability of occurrence of the most critical PSFs.
Furthermore, the AHP model allows to define the probability of occurrence of the most critical scenario or, as the results show in Figure 10, the most critical scenario is scenario B: Scenario A (47%%) and Scenario B (53%).
\n\nProbability of occurrence of the most critical scenario.
Considering the most critical PSF or PSF#1 a sensitivity analysis was performed to evaluate the variability of this factor and the robustness of the model. As shown in Figure 11 it emerges that if the vertical line is at 0.5 shows the scenario A is more likely. For any PSFs greater than that, the Scenario B is the more likely.
\nSensitivity analysis.
The general result or PSF#1 highlights that
This is a pilot study that is based on the awareness that the increasingly complexity of industrial plants and the need to analyze safety systems lead researchers to develop new methodological approach. In the present research the main gap of the qualitative approach of FRAM method was overcome with the integration of a multi-criteria decision-making method. The research proposes the integration of the traditional FRAM method with AHP. The integration of AHP with FRAM allows to investigate a new perspective in the field of risk management. The model was applied in a real case study to evaluate the performance of emergency operations in a petrochemical company. Considering the variability of each system function, the research numerically shows the level of variability generated by an upstream function on a downstream function. The results obtained are aimed at identifying function couplings that could generate high variability. Future development of research is the integration technological and organizational aspects, beyond human ones. Moreover, the model can be applied in different socio-technical systems where a high level of complexity requires the use of innovative tools. Thus, the proposed model will be tested in other situations or industrial settings.
\nThe authors declare no conflict of interest.
mRNAs are noncoding single-stranded RNA molecules that range from a length of 18 to 28 nucleotides. These molecules play an important role in posttranscriptional regulation by the inhibition of the expression of target genes by binding to mRNA [1]. Eukaryotic organisms, such as plants and animals, and some viruses express this type of molecules [2, 3]. Lin-4 is the first miRNA that was identified in
The biogenesis of miRNAs in plants and animals presents some differences. In both plants and animals, the precursors of miRNAs are polyadenylated caps and RNAs, and transcribed as for any coding RNA by RNA polymerase II (RNAPII) [5, 8]. However, in the plants, the primary transcript (pri-miRNA) that gives rise to the miRNA is produced by the nuclear RNAase dicer-like 1 (DCL1) and its accessory proteins SERRATE (SE) and hyponastic leaves (HYL1) [8]. Also, Drosha gene is absent in plants [5].
\nIn
The expression of miRNAs is regulated by transcription factors. Negative on TATA less 2 (NOT2) promotes the transcription of protein miRNA genes and facilitates efficient DCL1 recruitment in miRNA biogenesis [11]. Cell division cycle 5 (CDC5) acts as a positive transcription factor associating with miRNA genes [12]. Pleiotropic regulatory locus 1 (PRL1) has the ability to bind to DCL1 and pri-miRNAs. The miRNA duplex is transported to the cytoplasm by nuclear export factor
The miRNA target genes can be a single member of a gene family or regulate a multiple family members. Thus, multiple miRNA genes could be targeting a single member, with tissues and stage specificity, and/or a single miRNA gene could be regulating multiple family members. The spatial and temporal expression and abundance of mature miRNAs are tightly regulated; they vary greatly among different miRNAs; and the abundance also varies depending on the tissue types or developmental stages [13].
\nIn the cytoplasm of cells, the miRNAs regulate the expression of genes at the posttranscriptional level via mRNA degradation and/or translational repression [14]. Unlike animals, in plants, there is a perfect complementarity between miRNA and target mRNA [14]. To carry out the silencing, a ribonucleoprotein RNA-induced silencing complex (RISC) is formed [15]. AGO1, AGO2, AGO4, AGO7, and AGO10 slicer activity has been reported, even though AGO1 is associated with most miRNAs [16]. AGO1-catalyzed RNA cleavage (slicing) represses miRNA targets [17].
\nIn plants, miRNAs control the expression of genes that encode transcription factors, stress response proteins, and others, which have an impact on biological processes. The miRNAs regulate the biological processes in the plans such as maintenance of genome integrity, primary and secondary metabolism, development, signal transduction, signaling pathways, homeostasis, innate immunity, and adaptive responses to biotic and abiotic stress [18]. Secondary metabolites are a group of phytochemicals that regulate various processes related to the interaction of the plant with its environment [19]. These compounds include terpenoids, alkaloids, phenolics, glycosides, tannins, and saponins, and defend plants from several biotic an abiotic stressors [20]. Even though these types of compounds are synthesized by plants to help in self-defense, they have diverse industrial uses such as insecticides, dyes, flavoring compounds, and nutraceuticals having a positive effect on human health. Commercial importance has resulted in a great interest in studying possibilities of enhancing its production [21]. It is known that miRNAs control several biological processes at the posttranscriptional level. Currently, some studies reveal the role that miRNAs have in the regulation of secondary metabolic pathways [20]. Therefore, the production of compounds derived from secondary metabolism can be managed through the miRNAs. Since they are positively or negatively regulated, the production of desired metabolites can be induced, the production of toxic metabolites can be limited, and new metabolites can be produced [22].
\nComputational analysis carried out in two transcriptomes of Swertia resulted in the identification of miRNAs associated to secondary metabolites biosynthesis; miR-156a, miR-166a, miR-166b, miR-168, miR-11071, and miR-11320 targeting metabolic enzymes, such as aspartate aminotransferase, ribulose-phosphate 3-epimerase, acetyl-CoA acetyltransferase, phosphoglycerate mutase, and premnaspirodiene oxygenase, also include a gene encoding a homeobox-leucine zipper protein (HD-ZIP) with a possible association in secondary metabolites biosynthesis in
Flavonoids are secondary metabolites that possess a polyphenolic structure. Those compounds consist of hydroxylated phenolic substances having a benzo-𝛾-pyrone structure and derived of phenylpropanoid pathway [27]. Within the subgroups of the flavonoids are flavones, flavonols, flavanones, flavanonols, flavanols or catechins, anthocyanins, and chalcones [28]. For plants, this type of compounds is synthesized as a result of the interaction with the environment, other plants, and microorganisms. They have diverse biological functions as anti-oxidative, anti-inflammatory, anti-mutagenic, and anti-carcinogenic properties, which are structure dependent [28]. The above makes flavonoids a compound with nutraceutical, pharmaceutical, medicinal, and cosmetic applications [28]. The production of secondary metabolites is found in cases regulated by the miRNAs (Table 1). Little is known about the miRNAs involved in flavonoid biosynthesis. In
Plant species | \nmiRNA | \nTarget | \nFunction | \nReferences | \n
---|---|---|---|---|
Sunflower | \nmiR2911 | \nGamma-tocopherol methyl transferase | \nTocopherols biosynthesis | \n[29] | \n
miR156 | \nSPL transcription factor | \nAccumulation of anthocyanins, whereas reduced miR156 activity results in high levels of flavonols | \n[51] | \n|
miR395p-3p and miR858b | \nbHLH and MYB, respectively | \nProanthocyanidin biosynthesis | \n[30] | \n|
miRNAs (U436803, U977315, U805963, U3938865 and U4351355) | \nR2R3-MYB transcription factors | \nFlavonoid biosynthesis | \n[2, 3] | \n|
MicroRNA858a | \nR2R3-MYB transcription factors | \nFlavonoid biosynthesis | \n[31] | \n|
miR6194 and miR5655 | \nFlavanone 3-hydroxylase | \nFlavonols, anthocyanidins proanthocyanidins synthesis | \n[32] | \n|
miR1873/miR5532 | \nDihydroflavonol 4-reductase C/-hydroxyisoflavanone dehydratase | \nFlavonoid/isoflavonoid biosynthesis | \n[33] | \n|
Opium poppy ( | \npso-miR13, pso-miR2161, and pso-miR408 | \n7-O-methyltransferase, | \nBenzylisoquinoline alkaloids | \n[34] | \n
Tobacco | \nmiRX17, miRX27, miRX20, and miRX19 | \nQPT1, QPT2, CYP82E4, and PMT2 | \nNicotine biosynthesis and catabolism | \n[35] | \n
miR164 and miR171 | \nTaxane 13α hydroxylase and taxane 2α-O-benzoyltransferase | \nPaclitaxel biosynthetic genes | \n[36] | \n|
miR396b | \nTargets kaempferol 3-O-beta-D-galactosyltransferase | \nFlavonol glycosides | \n[37] | \n|
miR156 | \nBasic helix-loop-helix (bHLH) | \nFlavone/flavonol biosynthesis | \n[38] | \n|
iRNA-4995 | \n3-Deoxy-7-phosphoheptulonate synthase (DAHP synthase) | \nTerpenoid biosynthesis ultimately affecting the production of picroside-I | \n[39] | \n|
Korean ginseng ( | \nmiR854b and miR854c | \n3-Hydroxy-3-methylglutaryl-coenzyme A reductase (HMGR), farnesyl diphosphate synthase (FPS), geranyl-diphosphate synthase, squalene synthase, and squalene epoxidase (SE) | \n\n | [40] | \n
mir-5021 | \nMYB transcription factor, geranyl diphosphate synthase, GCPE protein, UDP-glucose iridoid glucosyltransferase | \nPrimary and secondary metabolism, Isoprenoid/terpenoid biosynthesis iridoid production in higher plants | \n[41] | \n|
miR7539, miR5021, and miR1134 | \nNontranscriptional factor proteins, such as DXS, HMGR, IDS, and IDI, essential to produce IPP and DMAPP | \nTerpenoid biosynthesis | \n[42] | \n|
miR7540, miR5183, miR6449, miR5255, miR5491, and miR6435 | \nR-linalool synthase, gibberellin 3-oxidase, ent-kaurene synthase, squalene epoxidase, beta-amyrin synthase, and germacrene A oxidase | \nMono-, sesqui-, di-, and tri-terpenoids biosynthesis | \n[42] | \n|
miR2919, miR5251, miR838, miR5021, and miR5658 | \nSPL7, SPL11, and ATHB13 TFs | \nTerpene biosynthesis | \n[43] | \n|
miRNA156 | \nSquamosa promoter binding protein-like (SPL) | \nSesquiterpene biosynthesis | \n[44] | \n|
miR156 | \nSPL transcription factor | \nModulate sesquiterpene synthase gene TPS21 responsible for the biosynthesis of (E)-β-caryophyllene | \n[44] | \n|
miR156, miR414, and miR5021 | \nBasic helix-loop-helix (bHLH) geranyl di-phosphate synthase subunit alpha-like protein (NACA), respectively | \nTerpenoid backbone biosynthesis, sesquiterpenoid and triterpenoid biosynthesis | \n[38] | \n|
miR-168, miR-11320, miR-166a, miR-11071, miR-156a and miR-166b | \nAcetyl-CoA acetyltransferase (AACT), aspartate aminotransferase (PHAT), premnaspirodiene oxygenase (PSO), ribulose-phosphate 3-epimerase (RPE), phosphoglycerate mutase (PGM), and a gene encoding homeobox-leucine zipper protein (HD-ZIP) | \nSecondary metabolites biosynthesis | \n[23] | \n|
miR163 | \nFamily of small molecules of methyltransferases | \nSecondary metabolism | \n[45] | \n|
miR393 | \nAuxin receptors (TIR1, AFB2 and AFB3) | \nIncrease of glucosinolate and decrease of camalexin | \n[46] | \n|
Potato | \nmirn79 | \nAP2/ERF transcription factor | \nJA-responsive secondary metabolites | \n[24] | \n
miRstv_7 | \nUDP-glycosyltransferase 76G1 (ugt76g1), kaurenoic acid hydroxylase (KAH), and kaurene oxidase (KO) | \nSteviol glycoside biosynthesis | \n[47] | \n|
miR826 and miR5090 | \nAOP2 | \nGlucosinolate biosynthesis | \n[48] | \n|
miR826 | \nAlkenyl hydroxyalkyl producing 2 | \nGlucosinolate synthesis | \n[49] | \n|
miR5072 | \nAcetyl-CoA C-acetyl transferase | \nTanshinones biosynthesis | \n[50] | \n
miRNA related to secondary metabolite production.
Alkaloids are naturally compounds that have one or more of their nitrogen atoms. Alkaloids are classified into different groups: indole, piperidine, tropane, purine, pyrrolizidine, imidazole, quinolizidine, isoquinoline, and pyrrolidine alkaloids [52]. Because of their toxicity, alkaloids act as defense compounds against diverse pathogens or herbivores. Understanding the regulation of alkaloid biosynthesis is crucial for its production. Target transcript identification analyses in Opium poppy (
Plant terpenoids secondary metabolites are synthesized from C5 precursors isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). They are classified according to the number of carbon atoms as monoterpenes (C10), sesquiterpenes (C15), diterpenes (C20), triterpenes (C30), carotenoids (C40), and polyprenols (>45) [53]. Like the alkaloids and the flavonoids, the biological characteristics and the applications of interest in the industry. Computational identification of miRNAs was done in six transcriptomes of
miRNAs were identified from
miRNAs are small molecules associated with developmental processes controlling gene expression. The mechanisms involved posttranscriptional and transductional processes. The miRNA secondary metabolism control is a relative new field of study; the knowledge of the regulation of secondary metabolism in plants will help to understand the production of these products in controlled systems. Some of these products have an important economical value because of their use in agricultural, food, and cosmetic industries making these areas (miRNA regulation) very attractive.
\nThe authors thank Universidad De la Salle Bajío campus Campestre for financial support. MVH thank to CONACyT for postdoctoral fellowship (288773).
\nThese Terms and Conditions outline the rules and regulations pertaining to the use of IntechOpen’s website www.intechopen.com and all the subdomains owned by IntechOpen located at 5 Princes Gate Court, London, SW7 2QJ, United Kingdom.
',metaTitle:"Terms and Conditions",metaDescription:"These terms and conditions outline the rules and regulations for the use of IntechOpen Website at https://intechopen.com and all its subdomains owned by Intech Limited located at 7th floor, 10 Lower Thames Street, London, EC3R 6AF, UK.",metaKeywords:null,canonicalURL:"/page/terms-and-conditions",contentRaw:'[{"type":"htmlEditorComponent","content":"By accessing the website at www.intechopen.com you are agreeing to be bound by these Terms of Service, all applicable laws and regulations, and agree that you are responsible for compliance with any applicable local laws. Use and/or access to this site is based on full agreement and compliance of these Terms. All materials contained on this website are protected by applicable copyright and trademark laws.
\\n\\nThe following terminology applies to these Terms and Conditions, Privacy Statement, Disclaimer Notice, and any or all Agreements:
\\n\\n“Client”, “Customer”, “You” and “Your” refers to you, the person accessing this website and accepting the Company’s Terms and Conditions;
\\n\\n“The Company”, “Ourselves”, “We”, “Our” and “Us”, refers to our Company, IntechOpen;
\\n\\n“Party”, “Parties”, or “Us”, refers to both the Client and ourselves, or either the Client or ourselves.
\\n\\nAll Terms refer to the offer, acceptance, and consideration of payment necessary to provide assistance to the Client in the most appropriate manner, whether by formal meetings of a fixed duration, or by any other agreed means, for the express purpose of meeting the Client’s needs in respect of provision of the Company’s stated services/products, and in accordance with, and subject to, the prevailing laws of the United Kingdom.
\\n\\nAny use of the above terminology, or other words in the singular, plural, capitalization and/or he/she or they, are taken as interchangeable.
\\n\\nUnless otherwise stated, IntechOpen and/or its licensors own the intellectual property rights for all materials on www.intechopen.com. All intellectual property rights are reserved. You may view, download, share, link and print pages from www.intechopen.com for your own personal use, subject to the restrictions set out in these Terms and Conditions.
\\n\\nWe employ the use of cookies. By using the IntechOpen website you consent to the use of cookies in accordance with IntechOpen’s Privacy Policy. Most modern day interactive websites use cookies to enable the retrieval of user details for each visit. On our site, cookies are predominantly used to enable functionality and ease of use for those visiting the site.
\\n\\nIn no circumstances shall IntechOpen or its suppliers be liable for any damages (including, without limitation, damages for loss of data or profit, or due to business interruption) arising out of the use, or inability to use, the materials on IntechOpen's websites, even if IntechOpen or an IntechOpen authorized representative has been notified orally or in writing of the possibility of such damage. Some jurisdictions do not allow limitations on implied warranties, or limitations of liability for consequential or incidental damages; consequently, these limitations may not apply to you.
\\n\\nIntechopen.com website content and services are provided on an "AS IS" and an "AS AVAILABLE" basis. Material appearing on www.intechopen.com could include minor technical, typographical, or photographic errors. IntechOpen may make changes to any material contained on its website at any time without notice.
\\n\\nIntechOpen has no formal affiliation to any external sites that link to www.intechopen.com, unless otherwise specifically stated. As such, it is not responsible for content that appears on any such sites. The inclusion of any link to IntechOpen does not imply endorsement by IntechOpen. Use of any such linked website is done solely at the user's own discretion.
\\n\\nWe reserve the right of ownership over our entire website www.intechopen.com, and all contents. By using our services, you agree to remove all links to our website immediately upon request. We also reserve the right to amend these Terms and Conditions and our linking policy at any time. By continuing to link to our website, you agree to be bound to, and abide by, these linking Terms and Conditions.
\\n\\nIf you find any link on our website, or any linked website, objectionable for any reason, please Contact Us. We will consider all requests to remove links but will have no obligation to do so.
\\n\\nWithout prior approval and express written permission, you may not create frames around our web pages or use other techniques that alter in any way the visual presentation or appearance of our website.
\\n\\nIntechOpen may revise its Terms of Service for its website at any time without notice. By using this website, you are agreeing to be bound by the current version of all Terms at the time of use.
\\n\\nThese Terms and Conditions are governed by and construed in accordance with the laws of the United Kingdom and you irrevocably submit to the exclusive jurisdiction of the courts in London, United Kingdom.
\\n\\nCroatian version of Terms and Conditions available here
\\n"}]'},components:[{type:"htmlEditorComponent",content:'By accessing the website at www.intechopen.com you are agreeing to be bound by these Terms of Service, all applicable laws and regulations, and agree that you are responsible for compliance with any applicable local laws. Use and/or access to this site is based on full agreement and compliance of these Terms. All materials contained on this website are protected by applicable copyright and trademark laws.
\n\nThe following terminology applies to these Terms and Conditions, Privacy Statement, Disclaimer Notice, and any or all Agreements:
\n\n“Client”, “Customer”, “You” and “Your” refers to you, the person accessing this website and accepting the Company’s Terms and Conditions;
\n\n“The Company”, “Ourselves”, “We”, “Our” and “Us”, refers to our Company, IntechOpen;
\n\n“Party”, “Parties”, or “Us”, refers to both the Client and ourselves, or either the Client or ourselves.
\n\nAll Terms refer to the offer, acceptance, and consideration of payment necessary to provide assistance to the Client in the most appropriate manner, whether by formal meetings of a fixed duration, or by any other agreed means, for the express purpose of meeting the Client’s needs in respect of provision of the Company’s stated services/products, and in accordance with, and subject to, the prevailing laws of the United Kingdom.
\n\nAny use of the above terminology, or other words in the singular, plural, capitalization and/or he/she or they, are taken as interchangeable.
\n\nUnless otherwise stated, IntechOpen and/or its licensors own the intellectual property rights for all materials on www.intechopen.com. All intellectual property rights are reserved. You may view, download, share, link and print pages from www.intechopen.com for your own personal use, subject to the restrictions set out in these Terms and Conditions.
\n\nWe employ the use of cookies. By using the IntechOpen website you consent to the use of cookies in accordance with IntechOpen’s Privacy Policy. Most modern day interactive websites use cookies to enable the retrieval of user details for each visit. On our site, cookies are predominantly used to enable functionality and ease of use for those visiting the site.
\n\nIn no circumstances shall IntechOpen or its suppliers be liable for any damages (including, without limitation, damages for loss of data or profit, or due to business interruption) arising out of the use, or inability to use, the materials on IntechOpen's websites, even if IntechOpen or an IntechOpen authorized representative has been notified orally or in writing of the possibility of such damage. Some jurisdictions do not allow limitations on implied warranties, or limitations of liability for consequential or incidental damages; consequently, these limitations may not apply to you.
\n\nIntechopen.com website content and services are provided on an "AS IS" and an "AS AVAILABLE" basis. Material appearing on www.intechopen.com could include minor technical, typographical, or photographic errors. IntechOpen may make changes to any material contained on its website at any time without notice.
\n\nIntechOpen has no formal affiliation to any external sites that link to www.intechopen.com, unless otherwise specifically stated. As such, it is not responsible for content that appears on any such sites. The inclusion of any link to IntechOpen does not imply endorsement by IntechOpen. Use of any such linked website is done solely at the user's own discretion.
\n\nWe reserve the right of ownership over our entire website www.intechopen.com, and all contents. By using our services, you agree to remove all links to our website immediately upon request. We also reserve the right to amend these Terms and Conditions and our linking policy at any time. By continuing to link to our website, you agree to be bound to, and abide by, these linking Terms and Conditions.
\n\nIf you find any link on our website, or any linked website, objectionable for any reason, please Contact Us. We will consider all requests to remove links but will have no obligation to do so.
\n\nWithout prior approval and express written permission, you may not create frames around our web pages or use other techniques that alter in any way the visual presentation or appearance of our website.
\n\nIntechOpen may revise its Terms of Service for its website at any time without notice. By using this website, you are agreeing to be bound by the current version of all Terms at the time of use.
\n\nThese Terms and Conditions are governed by and construed in accordance with the laws of the United Kingdom and you irrevocably submit to the exclusive jurisdiction of the courts in London, United Kingdom.
\n\nCroatian version of Terms and Conditions available here
\n'}]},successStories:{items:[]},authorsAndEditors:{filterParams:{sort:"featured,name"},profiles:[{id:"6700",title:"Dr.",name:"Abbass A.",middleName:null,surname:"Hashim",slug:"abbass-a.-hashim",fullName:"Abbass A. Hashim",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/6700/images/1864_n.jpg",biography:"Currently I am carrying out research in several areas of interest, mainly covering work on chemical and bio-sensors, semiconductor thin film device fabrication and characterisation.\nAt the moment I have very strong interest in radiation environmental pollution and bacteriology treatment. The teams of researchers are working very hard to bring novel results in this field. I am also a member of the team in charge for the supervision of Ph.D. students in the fields of development of silicon based planar waveguide sensor devices, study of inelastic electron tunnelling in planar tunnelling nanostructures for sensing applications and development of organotellurium(IV) compounds for semiconductor applications. I am a specialist in data analysis techniques and nanosurface structure. I have served as the editor for many books, been a member of the editorial board in science journals, have published many papers and hold many patents.",institutionString:null,institution:{name:"Sheffield Hallam University",country:{name:"United Kingdom"}}},{id:"54525",title:"Prof.",name:"Abdul Latif",middleName:null,surname:"Ahmad",slug:"abdul-latif-ahmad",fullName:"Abdul Latif Ahmad",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:null},{id:"20567",title:"Prof.",name:"Ado",middleName:null,surname:"Jorio",slug:"ado-jorio",fullName:"Ado Jorio",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Universidade Federal de Minas Gerais",country:{name:"Brazil"}}},{id:"47940",title:"Dr.",name:"Alberto",middleName:null,surname:"Mantovani",slug:"alberto-mantovani",fullName:"Alberto Mantovani",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:null},{id:"12392",title:"Mr.",name:"Alex",middleName:null,surname:"Lazinica",slug:"alex-lazinica",fullName:"Alex Lazinica",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/12392/images/7282_n.png",biography:"Alex Lazinica is the founder and CEO of IntechOpen. After obtaining a Master's degree in Mechanical Engineering, he continued his PhD studies in Robotics at the Vienna University of Technology. Here he worked as a robotic researcher with the university's Intelligent Manufacturing Systems Group as well as a guest researcher at various European universities, including the Swiss Federal Institute of Technology Lausanne (EPFL). During this time he published more than 20 scientific papers, gave presentations, served as a reviewer for major robotic journals and conferences and most importantly he co-founded and built the International Journal of Advanced Robotic Systems- world's first Open Access journal in the field of robotics. Starting this journal was a pivotal point in his career, since it was a pathway to founding IntechOpen - Open Access publisher focused on addressing academic researchers needs. Alex is a personification of IntechOpen key values being trusted, open and entrepreneurial. Today his focus is on defining the growth and development strategy for the company.",institutionString:null,institution:{name:"TU Wien",country:{name:"Austria"}}},{id:"19816",title:"Prof.",name:"Alexander",middleName:null,surname:"Kokorin",slug:"alexander-kokorin",fullName:"Alexander Kokorin",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/19816/images/1607_n.jpg",biography:"Alexander I. Kokorin: born: 1947, Moscow; DSc., PhD; Principal Research Fellow (Research Professor) of Department of Kinetics and Catalysis, N. Semenov Institute of Chemical Physics, Russian Academy of Sciences, Moscow.\r\nArea of research interests: physical chemistry of complex-organized molecular and nanosized systems, including polymer-metal complexes; the surface of doped oxide semiconductors. He is an expert in structural, absorptive, catalytic and photocatalytic properties, in structural organization and dynamic features of ionic liquids, in magnetic interactions between paramagnetic centers. The author or co-author of 3 books, over 200 articles and reviews in scientific journals and books. He is an actual member of the International EPR/ESR Society, European Society on Quantum Solar Energy Conversion, Moscow House of Scientists, of the Board of Moscow Physical Society.",institutionString:null,institution:{name:"Semenov Institute of Chemical Physics",country:{name:"Russia"}}},{id:"62389",title:"PhD.",name:"Ali Demir",middleName:null,surname:"Sezer",slug:"ali-demir-sezer",fullName:"Ali Demir Sezer",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/62389/images/3413_n.jpg",biography:"Dr. Ali Demir Sezer has a Ph.D. from Pharmaceutical Biotechnology at the Faculty of Pharmacy, University of Marmara (Turkey). He is the member of many Pharmaceutical Associations and acts as a reviewer of scientific journals and European projects under different research areas such as: drug delivery systems, nanotechnology and pharmaceutical biotechnology. Dr. Sezer is the author of many scientific publications in peer-reviewed journals and poster communications. Focus of his research activity is drug delivery, physico-chemical characterization and biological evaluation of biopolymers micro and nanoparticles as modified drug delivery system, and colloidal drug carriers (liposomes, nanoparticles etc.).",institutionString:null,institution:{name:"Marmara University",country:{name:"Turkey"}}},{id:"61051",title:"Prof.",name:"Andrea",middleName:null,surname:"Natale",slug:"andrea-natale",fullName:"Andrea Natale",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:null},{id:"100762",title:"Prof.",name:"Andrea",middleName:null,surname:"Natale",slug:"andrea-natale",fullName:"Andrea Natale",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"St David's Medical Center",country:{name:"United States of America"}}},{id:"107416",title:"Dr.",name:"Andrea",middleName:null,surname:"Natale",slug:"andrea-natale",fullName:"Andrea Natale",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Texas Cardiac Arrhythmia",country:{name:"United States of America"}}},{id:"64434",title:"Dr.",name:"Angkoon",middleName:null,surname:"Phinyomark",slug:"angkoon-phinyomark",fullName:"Angkoon Phinyomark",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/64434/images/2619_n.jpg",biography:"My name is Angkoon Phinyomark. I received a B.Eng. degree in Computer Engineering with First Class Honors in 2008 from Prince of Songkla University, Songkhla, Thailand, where I received a Ph.D. degree in Electrical Engineering. My research interests are primarily in the area of biomedical signal processing and classification notably EMG (electromyography signal), EOG (electrooculography signal), and EEG (electroencephalography signal), image analysis notably breast cancer analysis and optical coherence tomography, and rehabilitation engineering. I became a student member of IEEE in 2008. During October 2011-March 2012, I had worked at School of Computer Science and Electronic Engineering, University of Essex, Colchester, Essex, United Kingdom. In addition, during a B.Eng. I had been a visiting research student at Faculty of Computer Science, University of Murcia, Murcia, Spain for three months.\n\nI have published over 40 papers during 5 years in refereed journals, books, and conference proceedings in the areas of electro-physiological signals processing and classification, notably EMG and EOG signals, fractal analysis, wavelet analysis, texture analysis, feature extraction and machine learning algorithms, and assistive and rehabilitative devices. I have several computer programming language certificates, i.e. Sun Certified Programmer for the Java 2 Platform 1.4 (SCJP), Microsoft Certified Professional Developer, Web Developer (MCPD), Microsoft Certified Technology Specialist, .NET Framework 2.0 Web (MCTS). I am a Reviewer for several refereed journals and international conferences, such as IEEE Transactions on Biomedical Engineering, IEEE Transactions on Industrial Electronics, Optic Letters, Measurement Science Review, and also a member of the International Advisory Committee for 2012 IEEE Business Engineering and Industrial Applications and 2012 IEEE Symposium on Business, Engineering and Industrial Applications.",institutionString:null,institution:{name:"Joseph Fourier University",country:{name:"France"}}},{id:"55578",title:"Dr.",name:"Antonio",middleName:null,surname:"Jurado-Navas",slug:"antonio-jurado-navas",fullName:"Antonio Jurado-Navas",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/55578/images/4574_n.png",biography:"Antonio Jurado-Navas received the M.S. degree (2002) and the Ph.D. degree (2009) in Telecommunication Engineering, both from the University of Málaga (Spain). He first worked as a consultant at Vodafone-Spain. From 2004 to 2011, he was a Research Assistant with the Communications Engineering Department at the University of Málaga. In 2011, he became an Assistant Professor in the same department. From 2012 to 2015, he was with Ericsson Spain, where he was working on geo-location\ntools for third generation mobile networks. Since 2015, he is a Marie-Curie fellow at the Denmark Technical University. His current research interests include the areas of mobile communication systems and channel modeling in addition to atmospheric optical communications, adaptive optics and statistics",institutionString:null,institution:{name:"University of Malaga",country:{name:"Spain"}}}],filtersByRegion:[{group:"region",caption:"North America",value:1,count:5820},{group:"region",caption:"Middle and South America",value:2,count:5289},{group:"region",caption:"Africa",value:3,count:1761},{group:"region",caption:"Asia",value:4,count:10546},{group:"region",caption:"Australia and Oceania",value:5,count:909},{group:"region",caption:"Europe",value:6,count:15932}],offset:12,limit:12,total:119318},chapterEmbeded:{data:{}},editorApplication:{success:null,errors:{}},ofsBooks:{filterParams:{topicId:"20"},books:[{type:"book",id:"10672",title:"Nonlinear Optics",subtitle:null,isOpenForSubmission:!0,hash:"cfe87b713a8bee22c19361b86b03d506",slug:null,bookSignature:"Dr. Boris I. Lembrikov",coverURL:"https://cdn.intechopen.com/books/images_new/10672.jpg",editedByType:null,editors:[{id:"2359",title:"Dr.",name:"Boris",surname:"Lembrikov",slug:"boris-lembrikov",fullName:"Boris Lembrikov"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10674",title:"Topics on Quantum Information Science",subtitle:null,isOpenForSubmission:!0,hash:"d7481712cff0157cd8f849cba865727d",slug:null,bookSignature:"Prof. Sergio Curilef and Dr. Angel Ricardo Plastino",coverURL:"https://cdn.intechopen.com/books/images_new/10674.jpg",editedByType:null,editors:[{id:"125424",title:"Prof.",name:"Sergio",surname:"Curilef",slug:"sergio-curilef",fullName:"Sergio Curilef"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10852",title:"Electromagnetic Compatibility",subtitle:null,isOpenForSubmission:!0,hash:"f5d2cce3a2adbd5d108d3301ee97025b",slug:null,bookSignature:"Dr. Ahmed Kishk",coverURL:"https://cdn.intechopen.com/books/images_new/10852.jpg",editedByType:null,editors:[{id:"150146",title:"Dr.",name:"Ahmed",surname:"Kishk",slug:"ahmed-kishk",fullName:"Ahmed Kishk"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10921",title:"Plasma Science and Technology",subtitle:null,isOpenForSubmission:!0,hash:"c45670ef4b081fd9eebaf911b2b4627b",slug:null,bookSignature:"Dr. Aamir Shahzad",coverURL:"https://cdn.intechopen.com/books/images_new/10921.jpg",editedByType:null,editors:[{id:"288354",title:"Dr.",name:"Aamir",surname:"Shahzad",slug:"aamir-shahzad",fullName:"Aamir Shahzad"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10956",title:"Pulsed Lasers",subtitle:null,isOpenForSubmission:!0,hash:"88bd906b149fc3d1c5d6fdbd9916826c",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/10956.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}],filtersByTopic:[{group:"topic",caption:"Agricultural and Biological Sciences",value:5,count:28},{group:"topic",caption:"Biochemistry, Genetics and Molecular Biology",value:6,count:9},{group:"topic",caption:"Business, Management and Economics",value:7,count:3},{group:"topic",caption:"Chemistry",value:8,count:11},{group:"topic",caption:"Computer and Information Science",value:9,count:10},{group:"topic",caption:"Earth and Planetary Sciences",value:10,count:10},{group:"topic",caption:"Engineering",value:11,count:25},{group:"topic",caption:"Environmental Sciences",value:12,count:2},{group:"topic",caption:"Immunology and Microbiology",value:13,count:4},{group:"topic",caption:"Materials Science",value:14,count:7},{group:"topic",caption:"Mathematics",value:15,count:3},{group:"topic",caption:"Medicine",value:16,count:48},{group:"topic",caption:"Neuroscience",value:18,count:3},{group:"topic",caption:"Pharmacology, Toxicology and Pharmaceutical Science",value:19,count:3},{group:"topic",caption:"Physics",value:20,count:4},{group:"topic",caption:"Psychology",value:21,count:5},{group:"topic",caption:"Robotics",value:22,count:2},{group:"topic",caption:"Social Sciences",value:23,count:3},{group:"topic",caption:"Technology",value:24,count:1},{group:"topic",caption:"Veterinary Medicine and Science",value:25,count:2}],offset:12,limit:12,total:5},popularBooks:{featuredBooks:[],offset:0,limit:12,total:null},hotBookTopics:{hotBooks:[],offset:0,limit:12,total:null},publish:{},publishingProposal:{success:null,errors:{}},books:{featuredBooks:[{type:"book",id:"9154",title:"Spinal Deformities in Adolescents, Adults and Older Adults",subtitle:null,isOpenForSubmission:!1,hash:"313f1dffa803b60a14ff1e6966e93d91",slug:"spinal-deformities-in-adolescents-adults-and-older-adults",bookSignature:"Josette Bettany-Saltikov and Gokulakannan Kandasamy",coverURL:"https://cdn.intechopen.com/books/images_new/9154.jpg",editors:[{id:"94802",title:"Dr.",name:"Josette",middleName:null,surname:"Bettany-Saltikov",slug:"josette-bettany-saltikov",fullName:"Josette Bettany-Saltikov"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"7030",title:"Satellite Systems",subtitle:"Design, Modeling, Simulation and Analysis",isOpenForSubmission:!1,hash:"b9db6d2645ef248ceb1b33ea75f38e88",slug:"satellite-systems-design-modeling-simulation-and-analysis",bookSignature:"Tien Nguyen",coverURL:"https://cdn.intechopen.com/books/images_new/7030.jpg",editors:[{id:"210657",title:"Dr.",name:"Tien M.",middleName:"Manh",surname:"Nguyen",slug:"tien-m.-nguyen",fullName:"Tien M. Nguyen"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10201",title:"Post-Transition Metals",subtitle:null,isOpenForSubmission:!1,hash:"cc7f53ff5269916e3ce29f65a51a87ae",slug:"post-transition-metals",bookSignature:"Mohammed Muzibur Rahman, Abdullah Mohammed Asiri, Anish Khan, Inamuddin and Thamer Tabbakh",coverURL:"https://cdn.intechopen.com/books/images_new/10201.jpg",editors:[{id:"24438",title:"Prof.",name:"Mohammed Muzibur",middleName:null,surname:"Rahman",slug:"mohammed-muzibur-rahman",fullName:"Mohammed Muzibur Rahman"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10413",title:"A Collection of Papers on Chaos Theory and Its Applications",subtitle:null,isOpenForSubmission:!1,hash:"900b71b164948830fec3d6254b7881f7",slug:"a-collection-of-papers-on-chaos-theory-and-its-applications",bookSignature:"Paul Bracken and Dimo I. Uzunov",coverURL:"https://cdn.intechopen.com/books/images_new/10413.jpg",editors:[{id:"92883",title:"Prof.",name:"Paul",middleName:null,surname:"Bracken",slug:"paul-bracken",fullName:"Paul Bracken"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"9515",title:"Update in Geriatrics",subtitle:null,isOpenForSubmission:!1,hash:"913e16c0ae977474b283bbd4269564c8",slug:"update-in-geriatrics",bookSignature:"Somchai Amornyotin",coverURL:"https://cdn.intechopen.com/books/images_new/9515.jpg",editors:[{id:"185484",title:"Prof.",name:"Somchai",middleName:null,surname:"Amornyotin",slug:"somchai-amornyotin",fullName:"Somchai Amornyotin"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"8148",title:"Investment Strategies in Emerging New Trends in Finance",subtitle:null,isOpenForSubmission:!1,hash:"3b714d96a68d2acdfbd7b50aba6504ca",slug:"investment-strategies-in-emerging-new-trends-in-finance",bookSignature:"Reza Gharoie Ahangar and Asma Salman",coverURL:"https://cdn.intechopen.com/books/images_new/8148.jpg",editors:[{id:"91081",title:"Dr.",name:"Reza",middleName:null,surname:"Gharoie Ahangar",slug:"reza-gharoie-ahangar",fullName:"Reza Gharoie Ahangar"}],equalEditorOne:{id:"206443",title:"Prof.",name:"Asma",middleName:null,surname:"Salman",slug:"asma-salman",fullName:"Asma Salman",profilePictureURL:"https://mts.intechopen.com/storage/users/206443/images/system/206443.png",biography:"Professor Asma Salman is a blockchain developer and Professor of Finance at the American University in the Emirates, UAE. An Honorary Global Advisor at the Global Academy of Finance and Management, USA, she completed her MBA in Finance and Accounting and earned a Ph.D. in Finance from an AACSB member, AMBA accredited, School of Management at Harbin Institute of Technology, China. Her research credentials include a one-year residency at the Brunel Business School, Brunel University, UK. Prof. Salman also served as the Dubai Cohort supervisor for DBA students under the Nottingham Business School, UK, for seven years and is currently a Ph.D. supervisor at the University of Northampton, UK, where she is a visiting fellow. She also served on the Board of Etihad Airlines during 2019–2020. One of her recent articles on “Bitcoin and Blockchain” gained wide visibility and she is an active speaker on Fintech, blockchain, and crypto events around the GCC. She holds various professional certifications including Chartered Fintech Professional (USA), Certified Financial Manager (USA), Women in Leadership and Management in Higher Education, (UK), and Taxation GCC VAT Compliance, (UK). She recently won an award for “Blockchain Trainer of the Year” from Berkeley Middle East. Other recognitions include the Women Leadership Impact Award by H.E First Lady of Armenia, Research Excellence Award, and the Global Inspirational Women Leadership Award by H.H Sheikh Juma Bin Maktoum Juma Al Maktoum.",institutionString:"American University in the Emirates",position:null,outsideEditionCount:0,totalCites:0,totalAuthoredChapters:"2",totalChapterViews:"0",totalEditedBooks:"2",institution:{name:"American University in the Emirates",institutionURL:null,country:{name:"United Arab Emirates"}}},equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"8472",title:"Bioactive Compounds in Nutraceutical and Functional Food for Good Human Health",subtitle:null,isOpenForSubmission:!1,hash:"8855452919b8495810ef8e88641feb20",slug:"bioactive-compounds-in-nutraceutical-and-functional-food-for-good-human-health",bookSignature:"Kavita Sharma, Kanchan Mishra, Kula Kamal Senapati and Corina Danciu",coverURL:"https://cdn.intechopen.com/books/images_new/8472.jpg",editors:[{id:"197731",title:"Dr.",name:"Kavita",middleName:null,surname:"Sharma",slug:"kavita-sharma",fullName:"Kavita Sharma"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"9959",title:"Biomedical Signal and Image Processing",subtitle:null,isOpenForSubmission:!1,hash:"22b87a09bd6df065d78c175235d367c8",slug:"biomedical-signal-and-image-processing",bookSignature:"Yongxia Zhou",coverURL:"https://cdn.intechopen.com/books/images_new/9959.jpg",editors:[{id:"259308",title:"Dr.",name:"Yongxia",middleName:null,surname:"Zhou",slug:"yongxia-zhou",fullName:"Yongxia Zhou"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"9685",title:"Agroecosystems",subtitle:"Very Complex Environmental Systems",isOpenForSubmission:!1,hash:"c44f7b43a9f9610c243dc32300d37df6",slug:"agroecosystems-very-complex-environmental-systems",bookSignature:"Marcelo L. Larramendy and Sonia Soloneski",coverURL:"https://cdn.intechopen.com/books/images_new/9685.jpg",editors:[{id:"14764",title:"Dr.",name:"Marcelo L.",middleName:null,surname:"Larramendy",slug:"marcelo-l.-larramendy",fullName:"Marcelo L. Larramendy"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"8564",title:"Cell Interaction",subtitle:"Molecular and Immunological Basis for Disease Management",isOpenForSubmission:!1,hash:"98d7f080d80524285f091e72a8e92a6d",slug:"cell-interaction-molecular-and-immunological-basis-for-disease-management",bookSignature:"Bhawana Singh",coverURL:"https://cdn.intechopen.com/books/images_new/8564.jpg",editors:[{id:"315192",title:"Dr.",name:"Bhawana",middleName:null,surname:"Singh",slug:"bhawana-singh",fullName:"Bhawana Singh"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}}],latestBooks:[{type:"book",id:"9515",title:"Update in Geriatrics",subtitle:null,isOpenForSubmission:!1,hash:"913e16c0ae977474b283bbd4269564c8",slug:"update-in-geriatrics",bookSignature:"Somchai Amornyotin",coverURL:"https://cdn.intechopen.com/books/images_new/9515.jpg",editedByType:"Edited by",editors:[{id:"185484",title:"Prof.",name:"Somchai",middleName:null,surname:"Amornyotin",slug:"somchai-amornyotin",fullName:"Somchai Amornyotin"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"9021",title:"Novel Perspectives of Stem Cell Manufacturing and Therapies",subtitle:null,isOpenForSubmission:!1,hash:"522c6db871783d2a11c17b83f1fd4e18",slug:"novel-perspectives-of-stem-cell-manufacturing-and-therapies",bookSignature:"Diana Kitala and Ana Colette Maurício",coverURL:"https://cdn.intechopen.com/books/images_new/9021.jpg",editedByType:"Edited by",editors:[{id:"203598",title:"Ph.D.",name:"Diana",middleName:null,surname:"Kitala",slug:"diana-kitala",fullName:"Diana Kitala"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"7030",title:"Satellite Systems",subtitle:"Design, Modeling, Simulation and Analysis",isOpenForSubmission:!1,hash:"b9db6d2645ef248ceb1b33ea75f38e88",slug:"satellite-systems-design-modeling-simulation-and-analysis",bookSignature:"Tien Nguyen",coverURL:"https://cdn.intechopen.com/books/images_new/7030.jpg",editedByType:"Edited by",editors:[{id:"210657",title:"Dr.",name:"Tien M.",middleName:"Manh",surname:"Nguyen",slug:"tien-m.-nguyen",fullName:"Tien M. Nguyen"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10413",title:"A Collection of Papers on Chaos Theory and Its Applications",subtitle:null,isOpenForSubmission:!1,hash:"900b71b164948830fec3d6254b7881f7",slug:"a-collection-of-papers-on-chaos-theory-and-its-applications",bookSignature:"Paul Bracken and Dimo I. Uzunov",coverURL:"https://cdn.intechopen.com/books/images_new/10413.jpg",editedByType:"Edited by",editors:[{id:"92883",title:"Prof.",name:"Paul",middleName:null,surname:"Bracken",slug:"paul-bracken",fullName:"Paul Bracken"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"9154",title:"Spinal Deformities in Adolescents, Adults and Older Adults",subtitle:null,isOpenForSubmission:!1,hash:"313f1dffa803b60a14ff1e6966e93d91",slug:"spinal-deformities-in-adolescents-adults-and-older-adults",bookSignature:"Josette Bettany-Saltikov and Gokulakannan Kandasamy",coverURL:"https://cdn.intechopen.com/books/images_new/9154.jpg",editedByType:"Edited by",editors:[{id:"94802",title:"Dr.",name:"Josette",middleName:null,surname:"Bettany-Saltikov",slug:"josette-bettany-saltikov",fullName:"Josette Bettany-Saltikov"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"8148",title:"Investment Strategies in Emerging New Trends in Finance",subtitle:null,isOpenForSubmission:!1,hash:"3b714d96a68d2acdfbd7b50aba6504ca",slug:"investment-strategies-in-emerging-new-trends-in-finance",bookSignature:"Reza Gharoie Ahangar and Asma Salman",coverURL:"https://cdn.intechopen.com/books/images_new/8148.jpg",editedByType:"Edited by",editors:[{id:"91081",title:"Dr.",name:"Reza",middleName:null,surname:"Gharoie Ahangar",slug:"reza-gharoie-ahangar",fullName:"Reza Gharoie Ahangar"}],equalEditorOne:{id:"206443",title:"Prof.",name:"Asma",middleName:null,surname:"Salman",slug:"asma-salman",fullName:"Asma Salman",profilePictureURL:"https://mts.intechopen.com/storage/users/206443/images/system/206443.png",biography:"Professor Asma Salman is a blockchain developer and Professor of Finance at the American University in the Emirates, UAE. An Honorary Global Advisor at the Global Academy of Finance and Management, USA, she completed her MBA in Finance and Accounting and earned a Ph.D. in Finance from an AACSB member, AMBA accredited, School of Management at Harbin Institute of Technology, China. Her research credentials include a one-year residency at the Brunel Business School, Brunel University, UK. Prof. Salman also served as the Dubai Cohort supervisor for DBA students under the Nottingham Business School, UK, for seven years and is currently a Ph.D. supervisor at the University of Northampton, UK, where she is a visiting fellow. She also served on the Board of Etihad Airlines during 2019–2020. One of her recent articles on “Bitcoin and Blockchain” gained wide visibility and she is an active speaker on Fintech, blockchain, and crypto events around the GCC. She holds various professional certifications including Chartered Fintech Professional (USA), Certified Financial Manager (USA), Women in Leadership and Management in Higher Education, (UK), and Taxation GCC VAT Compliance, (UK). She recently won an award for “Blockchain Trainer of the Year” from Berkeley Middle East. Other recognitions include the Women Leadership Impact Award by H.E First Lady of Armenia, Research Excellence Award, and the Global Inspirational Women Leadership Award by H.H Sheikh Juma Bin Maktoum Juma Al Maktoum.",institutionString:"American University in the Emirates",position:null,outsideEditionCount:0,totalCites:0,totalAuthoredChapters:"2",totalChapterViews:"0",totalEditedBooks:"2",institution:{name:"American University in the Emirates",institutionURL:null,country:{name:"United Arab Emirates"}}},equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10201",title:"Post-Transition Metals",subtitle:null,isOpenForSubmission:!1,hash:"cc7f53ff5269916e3ce29f65a51a87ae",slug:"post-transition-metals",bookSignature:"Mohammed Muzibur Rahman, Abdullah Mohammed Asiri, Anish Khan, Inamuddin and Thamer Tabbakh",coverURL:"https://cdn.intechopen.com/books/images_new/10201.jpg",editedByType:"Edited by",editors:[{id:"24438",title:"Prof.",name:"Mohammed Muzibur",middleName:null,surname:"Rahman",slug:"mohammed-muzibur-rahman",fullName:"Mohammed Muzibur Rahman"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"9959",title:"Biomedical Signal and Image Processing",subtitle:null,isOpenForSubmission:!1,hash:"22b87a09bd6df065d78c175235d367c8",slug:"biomedical-signal-and-image-processing",bookSignature:"Yongxia Zhou",coverURL:"https://cdn.intechopen.com/books/images_new/9959.jpg",editedByType:"Edited by",editors:[{id:"259308",title:"Dr.",name:"Yongxia",middleName:null,surname:"Zhou",slug:"yongxia-zhou",fullName:"Yongxia Zhou"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"8472",title:"Bioactive Compounds in Nutraceutical and Functional Food for Good Human Health",subtitle:null,isOpenForSubmission:!1,hash:"8855452919b8495810ef8e88641feb20",slug:"bioactive-compounds-in-nutraceutical-and-functional-food-for-good-human-health",bookSignature:"Kavita Sharma, Kanchan Mishra, Kula Kamal Senapati and Corina Danciu",coverURL:"https://cdn.intechopen.com/books/images_new/8472.jpg",editedByType:"Edited by",editors:[{id:"197731",title:"Dr.",name:"Kavita",middleName:null,surname:"Sharma",slug:"kavita-sharma",fullName:"Kavita Sharma"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"8760",title:"Structure Topology and Symplectic Geometry",subtitle:null,isOpenForSubmission:!1,hash:"8974840985ec3652492c83e20233bf02",slug:"structure-topology-and-symplectic-geometry",bookSignature:"Kamal Shah and Min Lei",coverURL:"https://cdn.intechopen.com/books/images_new/8760.jpg",editedByType:"Edited by",editors:[{id:"231748",title:"Dr.",name:"Kamal",middleName:null,surname:"Shah",slug:"kamal-shah",fullName:"Kamal Shah"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}]},subject:{topic:{id:"1197",title:"Pharmaceutical Drug",slug:"pharmaceutical-drug",parent:{title:"Pharmacology",slug:"pharmacology-toxicology-and-pharmaceutical-science-pharmacology"},numberOfBooks:6,numberOfAuthorsAndEditors:141,numberOfWosCitations:285,numberOfCrossrefCitations:132,numberOfDimensionsCitations:361,videoUrl:null,fallbackUrl:null,description:null},booksByTopicFilter:{topicSlug:"pharmaceutical-drug",sort:"-publishedDate",limit:12,offset:0},booksByTopicCollection:[{type:"book",id:"9086",title:"Drug Repurposing",subtitle:"Hypothesis, Molecular Aspects and Therapeutic Applications",isOpenForSubmission:!1,hash:"5b13e06123db7a16dcdae682eb47ac66",slug:"drug-repurposing-hypothesis-molecular-aspects-and-therapeutic-applications",bookSignature:"Farid A. Badria",coverURL:"https://cdn.intechopen.com/books/images_new/9086.jpg",editedByType:"Edited by",editors:[{id:"41865",title:"Prof.",name:"Farid A.",middleName:null,surname:"Badria",slug:"farid-a.-badria",fullName:"Farid A. Badria"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"7110",title:"Opioids",subtitle:"From Analgesic Use to Addiction",isOpenForSubmission:!1,hash:"8bd70b93e5c8ff9ea766159555eb63da",slug:"opioids-from-analgesic-use-to-addiction",bookSignature:"Pilar Almela Rojo",coverURL:"https://cdn.intechopen.com/books/images_new/7110.jpg",editedByType:"Edited by",editors:[{id:"98258",title:"Dr.",name:"Pilar",middleName:null,surname:"Almela Rojo",slug:"pilar-almela-rojo",fullName:"Pilar Almela Rojo"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"7994",title:"Metformin",subtitle:null,isOpenForSubmission:!1,hash:"4763270256096f776a58d75658fe1d9b",slug:"metformin",bookSignature:"Anca Mihaela Pantea Stoian and Manfredi Rizzo",coverURL:"https://cdn.intechopen.com/books/images_new/7994.jpg",editedByType:"Edited by",editors:[{id:"243049",title:"Dr.",name:"Anca",middleName:null,surname:"Pantea Stoian",slug:"anca-pantea-stoian",fullName:"Anca Pantea Stoian"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"5525",title:"Pain Relief",subtitle:"From Analgesics to Alternative Therapies",isOpenForSubmission:!1,hash:"5ffdba8a1f402fe1b279cf05e2fa0aae",slug:"pain-relief-from-analgesics-to-alternative-therapies",bookSignature:"Cecilia Maldonado",coverURL:"https://cdn.intechopen.com/books/images_new/5525.jpg",editedByType:"Edited by",editors:[{id:"73432",title:"Dr.",name:"Cecilia",middleName:null,surname:"Maldonado",slug:"cecilia-maldonado",fullName:"Cecilia Maldonado"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"5173",title:"Anticoagulation Therapy",subtitle:null,isOpenForSubmission:!1,hash:"209b074c858a63f0b8c7533de6e6e8f8",slug:"anticoagulation-therapy",bookSignature:"Ozcan Basaran and Murat Biteker",coverURL:"https://cdn.intechopen.com/books/images_new/5173.jpg",editedByType:"Edited by",editors:[{id:"178766",title:"Dr.",name:"Ozcan",middleName:null,surname:"Basaran",slug:"ozcan-basaran",fullName:"Ozcan Basaran"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"2509",title:"Recent Advances in Novel Drug Carrier Systems",subtitle:null,isOpenForSubmission:!1,hash:"57c10c8e0b4bb01a815f2c42db01956e",slug:"recent-advances-in-novel-drug-carrier-systems",bookSignature:"Ali Demir Sezer",coverURL:"https://cdn.intechopen.com/books/images_new/2509.jpg",editedByType:"Edited by",editors:[{id:"62389",title:"PhD.",name:"Ali Demir",middleName:null,surname:"Sezer",slug:"ali-demir-sezer",fullName:"Ali Demir Sezer"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}],booksByTopicTotal:6,mostCitedChapters:[{id:"40253",doi:"10.5772/50486",title:"Lipid Nanoparticulate Drug Delivery Systems: A Revolution in Dosage Form Design and Development",slug:"lipid-nanoparticulate-drug-delivery-systems-a-revolution-in-dosage-form-design-and-development",totalDownloads:10501,totalCrossrefCites:11,totalDimensionsCites:73,book:{slug:"recent-advances-in-novel-drug-carrier-systems",title:"Recent Advances in Novel Drug Carrier Systems",fullTitle:"Recent Advances in Novel Drug Carrier Systems"},signatures:"Anthony A. Attama, Mumuni A. Momoh and Philip F. Builders",authors:[{id:"142947",title:"Prof.",name:"Anthony",middleName:null,surname:"Attama",slug:"anthony-attama",fullName:"Anthony Attama"}]},{id:"40262",doi:"10.5772/51384",title:"Nanotechnology in Drug Delivery",slug:"nanotechnology-in-drug-delivery",totalDownloads:14776,totalCrossrefCites:10,totalDimensionsCites:43,book:{slug:"recent-advances-in-novel-drug-carrier-systems",title:"Recent Advances in Novel Drug Carrier Systems",fullTitle:"Recent Advances in Novel Drug Carrier Systems"},signatures:"Martins Ochubiojo Emeje, Ifeoma Chinwude Obidike, Ekaete Ibanga Akpabio and Sabinus Ifianyi Ofoefule",authors:[{id:"94311",title:"Prof.",name:"Martins",middleName:"Ochubiojo",surname:"Emeje",slug:"martins-emeje",fullName:"Martins Emeje"}]},{id:"40281",doi:"10.5772/52115",title:"Magnetic Nanoparticles: Synthesis, Surface Modifications and Application in Drug Delivery",slug:"magnetic-nanoparticles-synthesis-surface-modifications-and-application-in-drug-delivery",totalDownloads:11934,totalCrossrefCites:15,totalDimensionsCites:33,book:{slug:"recent-advances-in-novel-drug-carrier-systems",title:"Recent Advances in Novel Drug Carrier Systems",fullTitle:"Recent Advances in Novel Drug Carrier Systems"},signatures:"Seyda Bucak, Banu Yavuztürk and Ali Demir Sezer",authors:[{id:"62389",title:"PhD.",name:"Ali Demir",middleName:null,surname:"Sezer",slug:"ali-demir-sezer",fullName:"Ali Demir Sezer"},{id:"129638",title:"Prof.",name:"Seyda",middleName:null,surname:"Bucak",slug:"seyda-bucak",fullName:"Seyda Bucak"}]}],mostDownloadedChaptersLast30Days:[{id:"72744",title:"Drug Repurposing (DR): An Emerging Approach in Drug Discovery",slug:"drug-repurposing-dr-an-emerging-approach-in-drug-discovery",totalDownloads:954,totalCrossrefCites:2,totalDimensionsCites:2,book:{slug:"drug-repurposing-hypothesis-molecular-aspects-and-therapeutic-applications",title:"Drug Repurposing",fullTitle:"Drug Repurposing - Hypothesis, Molecular Aspects and Therapeutic Applications"},signatures:"Mithun Rudrapal, Shubham J. Khairnar and Anil G. Jadhav",authors:[{id:"314279",title:"Dr.",name:"Mithun",middleName:null,surname:"Rudrapal",slug:"mithun-rudrapal",fullName:"Mithun Rudrapal"}]},{id:"40262",title:"Nanotechnology in Drug Delivery",slug:"nanotechnology-in-drug-delivery",totalDownloads:14776,totalCrossrefCites:10,totalDimensionsCites:43,book:{slug:"recent-advances-in-novel-drug-carrier-systems",title:"Recent Advances in Novel Drug Carrier Systems",fullTitle:"Recent Advances in Novel Drug Carrier Systems"},signatures:"Martins Ochubiojo Emeje, Ifeoma Chinwude Obidike, Ekaete Ibanga Akpabio and Sabinus Ifianyi Ofoefule",authors:[{id:"94311",title:"Prof.",name:"Martins",middleName:"Ochubiojo",surname:"Emeje",slug:"martins-emeje",fullName:"Martins Emeje"}]},{id:"51569",title:"Prothrombin Complex Concentrate, a General Antidote for Oral Anticoagulation",slug:"prothrombin-complex-concentrate-a-general-antidote-for-oral-anticoagulation",totalDownloads:1754,totalCrossrefCites:0,totalDimensionsCites:1,book:{slug:"anticoagulation-therapy",title:"Anticoagulation Therapy",fullTitle:"Anticoagulation Therapy"},signatures:"Herm Jan M. Brinkman",authors:[{id:"180438",title:"Dr.",name:"Herm Jan",middleName:null,surname:"Brinkman",slug:"herm-jan-brinkman",fullName:"Herm Jan Brinkman"}]},{id:"40265",title:"Gene Delivery Systems: Recent Progress in Viral and Non-Viral Therapy",slug:"gene-delivery-systems-recent-progress-in-viral-and-non-viral-therapy",totalDownloads:8330,totalCrossrefCites:13,totalDimensionsCites:27,book:{slug:"recent-advances-in-novel-drug-carrier-systems",title:"Recent Advances in Novel Drug Carrier Systems",fullTitle:"Recent Advances in Novel Drug Carrier Systems"},signatures:"Erdal Cevher, Ali Demir Sezer and Emre Şefik Çağlar",authors:[{id:"62389",title:"PhD.",name:"Ali Demir",middleName:null,surname:"Sezer",slug:"ali-demir-sezer",fullName:"Ali Demir Sezer"},{id:"129634",title:"Prof.",name:"Erdal",middleName:null,surname:"Cevher",slug:"erdal-cevher",fullName:"Erdal Cevher"}]},{id:"68829",title:"Metformin Indications, Dosage, Adverse Reactions, and Contraindications",slug:"metformin-indications-dosage-adverse-reactions-and-contraindications",totalDownloads:505,totalCrossrefCites:0,totalDimensionsCites:1,book:{slug:"metformin",title:"Metformin",fullTitle:"Metformin"},signatures:"Roxana Adriana Stoica, Diana Simona Ștefan, Manfredi Rizzo, Andra Iulia Suceveanu, Adrian Paul Suceveanu, Cristian Serafinceanu and Anca Pantea-Stoian",authors:null},{id:"54987",title:"Analgesic Potential of Extracts and Derived Natural Products from Medicinal Plants",slug:"analgesic-potential-of-extracts-and-derived-natural-products-from-medicinal-plants",totalDownloads:1915,totalCrossrefCites:2,totalDimensionsCites:4,book:{slug:"pain-relief-from-analgesics-to-alternative-therapies",title:"Pain Relief",fullTitle:"Pain Relief - From Analgesics to Alternative Therapies"},signatures:"Abdur Rauf, Noor Jehan, Zarka Ahmad and Mohammad S. Mubarak",authors:[{id:"192295",title:"Dr.",name:"Abdur",middleName:null,surname:"Rauf",slug:"abdur-rauf",fullName:"Abdur Rauf"},{id:"207128",title:"Dr.",name:"Noor",middleName:null,surname:"Jehan",slug:"noor-jehan",fullName:"Noor Jehan"},{id:"207129",title:"Dr.",name:"Zarka",middleName:null,surname:"Ahmad",slug:"zarka-ahmad",fullName:"Zarka Ahmad"},{id:"207131",title:"Prof.",name:"Mohammad S.",middleName:null,surname:"Mubarak",slug:"mohammad-s.-mubarak",fullName:"Mohammad S. Mubarak"}]},{id:"71037",title:"New Insight into Metformin Mechanism of Action and Clinical Application",slug:"new-insight-into-metformin-mechanism-of-action-and-clinical-application",totalDownloads:518,totalCrossrefCites:1,totalDimensionsCites:2,book:{slug:"metformin",title:"Metformin",fullTitle:"Metformin"},signatures:"Yun Yan, Karen L. Kover and Wayne V. Moore",authors:null},{id:"40264",title:"Niosomes as Carrier in Dermal Drug Delivery",slug:"niosomes-as-carrier-in-dermal-drug-delivery",totalDownloads:9446,totalCrossrefCites:9,totalDimensionsCites:11,book:{slug:"recent-advances-in-novel-drug-carrier-systems",title:"Recent Advances in Novel Drug Carrier Systems",fullTitle:"Recent Advances in Novel Drug Carrier Systems"},signatures:"Yahya Rahimpour and Hamed Hamishehkar",authors:[{id:"149506",title:"Prof.",name:"Hamed",middleName:null,surname:"Hamishehkar",slug:"hamed-hamishehkar",fullName:"Hamed Hamishehkar"},{id:"158708",title:"Dr.",name:"Yahya",middleName:null,surname:"Rahimpour",slug:"yahya-rahimpour",fullName:"Yahya Rahimpour"}]},{id:"71075",title:"Metformin Activity against Breast Cancer: Mechanistic Differences by Molecular Subtype and Metabolic Conditions",slug:"metformin-activity-against-breast-cancer-mechanistic-differences-by-molecular-subtype-and-metabolic-",totalDownloads:341,totalCrossrefCites:1,totalDimensionsCites:1,book:{slug:"metformin",title:"Metformin",fullTitle:"Metformin"},signatures:"Reema S. Wahdan-Alaswad and Ann D. Thor",authors:null},{id:"53992",title:"Pharmacologic Management of Low Back Pain",slug:"pharmacologic-management-of-low-back-pain",totalDownloads:1302,totalCrossrefCites:0,totalDimensionsCites:0,book:{slug:"pain-relief-from-analgesics-to-alternative-therapies",title:"Pain Relief",fullTitle:"Pain Relief - From Analgesics to Alternative Therapies"},signatures:"Dallas Schepers",authors:[{id:"193688",title:"Dr.",name:"Dallas",middleName:null,surname:"Schepers",slug:"dallas-schepers",fullName:"Dallas Schepers"}]}],onlineFirstChaptersFilter:{topicSlug:"pharmaceutical-drug",limit:3,offset:0},onlineFirstChaptersCollection:[],onlineFirstChaptersTotal:0},preDownload:{success:null,errors:{}},aboutIntechopen:{},privacyPolicy:{},peerReviewing:{},howOpenAccessPublishingWithIntechopenWorks:{},sponsorshipBooks:{sponsorshipBooks:[],offset:0,limit:8,total:null},route:{name:"chapter.detail",path:"/books/operations-management-emerging-trend-in-the-digital-era/the-analytic-functional-resonance-analysis-to-improve-safety-management",hash:"",query:{},params:{book:"operations-management-emerging-trend-in-the-digital-era",chapter:"the-analytic-functional-resonance-analysis-to-improve-safety-management"},fullPath:"/books/operations-management-emerging-trend-in-the-digital-era/the-analytic-functional-resonance-analysis-to-improve-safety-management",meta:{},from:{name:null,path:"/",hash:"",query:{},params:{},fullPath:"/",meta:{}}}},function(){var e;(e=document.currentScript||document.scripts[document.scripts.length-1]).parentNode.removeChild(e)}()