Open access peer-reviewed Edited Volume

Non-Proteinogenic Amino Acids

Edited by Nina Filip

Grigore T. Popa University of Medicine and Pharmacy, Romania


The first description of homocysteine (Hcy), a non-proteinogenic amino acid, was introduced in a case study more than 70 years ago. In recent years, numerous studies have shown a positive correlation between serum levels and various diseases, especially vascular pathology. Vitamins B6, B12, and folic acid play a major role in controlling homocysteine levels. In this book are presented both methods for the determination of homocysteine and its involvement in human pathology. Homocysteine levels can be taken as an early indicator for the detection of cardiovascular diseases because Hcy levels increase after a myocardial infarction or stroke.

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Non-Proteinogenic Amino AcidsEdited by Nina Filip

Published: December 5th 2018

DOI: 10.5772/intechopen.71648

ISBN: 978-1-78984-729-1

Print ISBN: 978-1-78984-728-4

eBook (PDF) ISBN: 978-1-83881-597-4

Copyright year: 2018

Books open for chapter submissions

2479 Total Chapter Downloads

2 Web of Science Citations

1 Dimensions Citations


Open access peer-reviewed

1. Introductory Chapter: General Aspects Regarding Homocysteine

By Nina Filip and Cristina-Elena Iancu


Open access peer-reviewed

2. HPLC Analysis of Homocysteine and Related Compounds

By Mitsuhiro Wada, Shinichi Nakamura and Kenichiro Nakashima


Open access peer-reviewed

3. Is Homocysteine a Marker or a Risk Factor: A Question Still Waits for an Answer

By Cristiana Filip, Elena Albu, Hurjui Ion, Catalina Filip, Cuciureanu Magda, Radu Florin Popa, Demetra Gabriela Socolov, Ovidiu Alexa and Alexandru Filip


Open access peer-reviewed

4. How Homocysteine Modulates the Function of Osteoblasts and Osteocytes

By Viji Vijayan and Sarika Gupta


Edited Volume and chapters are indexed in

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  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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