Open access peer-reviewed Edited Volume

New Insights into Toxicity and Drug Testing

This book "New Insights into Toxicity and Drug Testing" covers all emerging technologies (profiling technologies, 3D cultures, next generation sequencing etc.), available methods and models to evaluate candidate drugs and medicinal plants with reference to toxicity, drug testing and development. This book is an original contribution of experts from different parts of the globe and the in-depth information will be a significant resource for scientists and physicians who are directly dealing with drugs / medicines and human life.

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New Insights into Toxicity and Drug TestingEdited by Sivakumar Joghi Thatha Gowder

Published: January 23rd 2013

DOI: 10.5772/55886

ISBN: 978-953-51-0946-4

Copyright year: 2013

Books open for chapter submissions

27411 Total Chapter Downloads

32 Crossref Citations

39 Web of Science Citations

86 Dimensions Citations

chaptersDownloads

Open access peer-reviewed

1. Pre-Clinical Assessment of the Potential Intrinsic Hepatotoxicity of Candidate Drugs

By Jacob John van Tonder, Vanessa Steenkamp and Mary Gulumian

2808

Open access peer-reviewed

2. The Kidney Vero-E6 Cell Line: A Suitable Model to Study the Toxicity of Microcystins

By Carina Menezes, Elisabete Valério and Elsa Dias

2264

Open access peer-reviewed

3. Why are Early Life Stages of Aquatic Organisms more Sensitive to Toxicants than Adults?

By Azad Mohammed

2219

Open access peer-reviewed

4. Screening of Herbal Medicines for Potential Toxicities

By Obidike Ifeoma and Salawu Oluwakanyinsola

5456

Open access peer-reviewed

5. New Trends in Genotoxicity Testing of Herbal Medicinal Plants

By Hala M. Abdelmigid

2309

Open access peer-reviewed

6. Animal Models in Drug Development

By Ray Greek

3117

Open access peer-reviewed

7. Renal Transporters and Biomarkers in Safety Assessment

By P.D. Ward, D. La and J.E. McDuffie

2245

Open access peer-reviewed

8. Autophagy: A Possible Defense Mechanism in Parkinson's Disease?

By Rosa A. González-Polo, Rubén Gómez-Sánchez, Lydia Sánchez- Erviti, José M Bravo-San Pedro, Elisa Pizarro-Estrella, Mireia Niso- Santano and José M. Fuentes

1738

Open access peer-reviewed

9. Physiologically Based Pharmacokinetic Modeling: A Tool for Understanding ADMET Properties and Extrapolating to Human

By Micaela B. Reddy, Harvey J. Clewell III, Thierry Lave and Melvin E. Andersen

3002

Open access peer-reviewed

10. Plasma Methadone Level Monitoring in Methadone Maintenance Therapy: A Personalised Methadone Therapy

By Nasir Mohamad, Roslanuddin Mohd Salehuddin, Basyirah Ghazali, Nor Hidayah Abu Bakar, Nurfadhlina Musa, Muslih Abdulkarim Ibrahim, Liyana Hazwani Mohd Adnan, Ahmad Rashidi and Rusli Ismail

2253

Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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