Open access peer-reviewed Edited Volume

New Insights into Inflammatory Bowel Disease

The incidence of chronic inflammatory and autoimmune diseases is steadily increasing. Inflammatory bowel disease (IBD) is one example of a chronic inflammatory disease, which primarily affects the intestine but may also affect extraintestinal organs. The exact pathogenesis of IBD is currently unknown. However, it is clear that the pathogenesis is complex, involving barrier defects, changes in the intestinal microbiome, and chronic immune activation. This book aims to summarize basic aspects of these complex interactions between barrier function, microbiome, and the immune system. Of note, there is currently no cure for IBD. However, several therapies have evolved in the last years, which are overall able to-at least temporarily-suppress IBD. These therapies and the underlying mechanism are discussed.

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New Insights into Inflammatory Bowel DiseaseEdited by Samuel Huber

Published: October 26th 2016

DOI: 10.5772/61540

ISBN: 978-953-51-2755-0

Print ISBN: 978-953-51-2754-3

eBook (PDF) ISBN: 978-953-51-4167-9

Copyright year: 2016

Books open for chapter submissions

16836 Total Chapter Downloads

6 Crossref Citations

8 Web of Science Citations

13 Dimensions Citations


Open access peer-reviewed

1. Inflammatory Bowel Disease: Epidemiology

By Sumant S. Arora and Talha A. Malik


Open access peer-reviewed

2. Inflammatory Bowel Disease: The Association of Inflammatory Cytokine Gene Polymorphisms

By Abdulrahman Al-Robayan, Misbahul Arfin, Ebtissam Saleh Al- Meghaiseeb, Reem Al-Amro and Abdulrahman K Al-Asmari


Open access peer-reviewed

3. Genetic and Serological Markers in Identifying Unclassified Colitis

By Valerie A. Fenech, John Schembri, Pierre Ellul, Godfrey Grech and Neville Azzopardi


Open access peer-reviewed

4. Cytokines in Inflamed Mucosa of IBD Patients

By Tsvetelina Velikova, Dobroslav Kyurkchiev, Ekaterina Ivanova- Todorova, Zoya Spassova, Spaska Stanilova and Iskra Altankova


Open access peer-reviewed

5. Interleukin 23 in IBD Pathogenesis

By Ahmet Eken and Mohamed Oukka


Open access peer-reviewed

6. Cytokines and Nitric Oxide in Immunopathogenesis of IBD and Potential Therapeutic Approaches

By Imene Soufli, Ryma Toumi, Hayet Rafa and Chafia Touil-Boukoffa


Open access peer-reviewed

7. MicroRNA in Inflammatory Bowel Disease

By Kurt Fisher and Jingmei Lin


Open access peer-reviewed

8. Intestinal Fibroblast/Myofibroblast TRP Channels in Inflammatory Bowel Disease

By Lin Hai Kurahara, Keizo Hiraishi, Kunihiko Aoyagi, Yaopeng Hu, Miho Sumiyoshi and Ryuji Inoue


Open access peer-reviewed

9. Microbial Neuro-Immune Interactions and the Pathophysiology of IBD

By Mònica Aguilera and Silvia Melgar


Open access peer-reviewed

10. Oral Tacrolimus in Patients with Ulcerative Colitis

By Takuya Inoue, Kazuki Kakimoto and Kazuhide Higuchi


Open access peer-reviewed

11. Probiotics and Crohn’s Disease

By Karen Kroeker and Cathy Lu


Open access peer-reviewed

12. Autologous and Allogeneic Stem Cell Transplantation for Treatment of Crohn’s Fistulae

By Fernando de la Portilla, Ana M. García‐Cabrera, Rosa M. Rodríguez‐ Jiménez, Maria L. Reyes and Damian García‐Olmo


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI
  • BKCI
  • BIOSIS Previews

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