Open access peer-reviewed Edited Volume

Neurodegenerative Diseases

Edited by Uday Kishore

Brunel University London, United Kingdom

This book highlights the pathophysiological complexities of the mechanisms and factors that are likely to be involved in a range of neuroinflammatory and neurodegenerative diseases including Alzheimer's disease, other Dementia, Parkinson Diseases and Multiple Sclerosis. The spectrum of diverse factors involved in neurodegeneration, such as protein aggregation, oxidative stress, caspases and secretase, regulators, cholesterol, zinc, microglia, astrocytes, oligodendrocytes, etc, have been discussed in the context of disease progression. In addition, novel approaches to therapeutic interventions have also been presented. It is hoped that students, scientists and clinicians shall find this very informative book immensely useful and thought-provoking.

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IntechOpen
Neurodegenerative DiseasesEdited by Uday Kishore

Published: May 15th 2013

DOI: 10.5772/45957

ISBN: 978-953-51-1088-0

eBook (PDF) ISBN: 978-953-51-7146-1

Copyright year: 2013

Books open for chapter submissions

60102 Total Chapter Downloads

39 Crossref Citations

50 Web of Science Citations

87 Dimensions Citations

chaptersDownloads

Open access peer-reviewed

1. Alzheimer’s Disease: A Clinical Perspective

By Weili Xu, Anna Marseglia, Camilla Ferrari and Hui-Xin Wang

2655

Open access peer-reviewed

2. Late-Onset Alzheimer's Disease: Risk Factors, Clinical Diagnosis and the Search for Biomarkers

By Marisol Herrera-Rivero

2239

Open access peer-reviewed

3. Role of Protein Aggregation in Neurodegenerative Diseases

By Yusuf Tutar, Aykut Özgür and Lütfi Tutar

3357

Open access peer-reviewed

4. Role of Oxidative Stress in Aβ Animal Model of Alzheimer's Disease: Vicious Circle of Apoptosis, Nitric Oxide and Age

By Ferihan Cetin

2151

Open access peer-reviewed

5. Alterations of Mitochondria and Golgi Apparatus Are Related to Synaptic Pathology in Alzheimer's Disease

By Stavros J. Baloyannis

2248

Open access peer-reviewed

6. Caspases in Alzheimer’s Disease

By Yan Zhang

2012

Open access peer-reviewed

7. Brain Reserve Regulators in Alzheimer’s Disease

By Ivana Delalle

1528

Open access peer-reviewed

8. Cholesterol and Alzheimer's Disease

By Iuliana Nicola-Antoniu

1959

Open access peer-reviewed

9. Emerging Therapeutic Strategies in Alzheimer's Disease

By Tomohiro Chiba

3206

Open access peer-reviewed

10. Dropping the BACE: Beta Secretase (BACE1) as an Alzheimer’s Disease Intervention Target

By Justin Read and Cenk Suphioglu

2707

Open access peer-reviewed

11. QSAR Analysis of Purine-Type and Propafenone-Type Substrates of P-Glycoprotein Targeting β-Amyloid Clearance

By Jie Yang and Jie Chen

1271

Open access peer-reviewed

12. Therapeutic Interventions in Alzheimer Disease

By Analava Mitra and Baishakhi Dey

2492

Open access peer-reviewed

13. Other Dementias

By Abhishek Shastri, Domenico Marco Bonifati and Uday Kishore

1698

Open access peer-reviewed

14. The Role of Epigenetics in Neurodegenerative Diseases

By Luca Lovrečić, Aleš Maver, Maja Zadel and Borut Peterlin

3582

Open access peer-reviewed

15. Plasma Membrane Channels Formed by Connexins or Pannexins in Microglia: Possible Role in the Inflamed Brain

By Juan A. Orellana

1702

Open access peer-reviewed

16. Influence of Obesity on Neurodegenerative Diseases

By Rana Awada , Avinash Parimisetty and Christian Lefebvre d’Hellencourt

2604

Open access peer-reviewed

17. Electro-Physiological Approaches to Monitoring Neuro- Degenerative Diseases

By Manuel J. Rojas, Camilo Orozco and Francisco Olea

1688

Open access peer-reviewed

18. Oxidative Changes and Possible Effects of Polymorphism of Antioxidant Enzymes in Neurodegenerative Disease

By Eva Babusikova, Andrea Evinova, Jozef Hatok, Dusan Dobrota and Jana Jurecekova

2721

Open access peer-reviewed

19. Intermediate Filaments in Neurodegenerative Diseases

By Rodolphe Perrot and Joel Eyer

1747

Open access peer-reviewed

20. Astrocytes Role in Parkinson: A Double-Edged Sword

By Ricardo Cabezas, Marco Fidel Avila, Daniel Torrente, Ramon Santos El-Bachá, Ludis Morales, Janneth Gonzalez and George E. Barreto

3995

Open access peer-reviewed

21. Zinc and Neurodegenerative Diseases

By Masahiro Kawahara, Keiko Konoha, Hironari Koyama, Susumu Ohkawara and Yutaka Sadakane

2375

Open access peer-reviewed

22. Oligodendrocyte Metabolic Stress in Neurodegeneration

By Daniel Radecki and Alexander Gow

1944

Open access peer-reviewed

23. Spinal Muscular Atrophy: Classification, Diagnosis, Background, Molecular Mechanism and Development of Therapeutics

By Faraz Tariq Farooq, Martin Holcik and Alex MacKenzie

3259

Open access peer-reviewed

24. Pharmacological Treatment of Acute Ischemic Stroke

By Humberto Mestre, Yael Cohen-Minian, Daniel Zajarias-Fainsod and Antonio Ibarra

2860

Open access peer-reviewed

25. Cognitive Dysfunction Syndrome in Senior Dogs

By Camilo Orozco Sanabria, Francisco Olea and Manuel Rojas

2111

Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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