Open access peer-reviewed Edited Volume

Molecular Targets of CNS Tumors

Edited by Miklos Garami

Semmelweis University, Hungary

Molecular Targets of CNS Tumors is a selected review of Central Nervous System (CNS) tumors with particular emphasis on signaling pathway of the most common CNS tumor types. To develop drugs which specifically attack the cancer cells requires an understanding of the distinct characteristics of those cells. Additional detailed information is provided on selected signal pathways in CNS tumors.

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Molecular Targets of CNS TumorsEdited by Miklos Garami

Published: September 22nd 2011

DOI: 10.5772/1047

ISBN: 978-953-307-736-9

eBook (PDF) ISBN: 978-953-51-6496-8

Copyright year: 2011

Books open for chapter submissions

69695 Total Chapter Downloads

12 Crossref Citations

54 Web of Science Citations

56 Dimensions Citations


Open access peer-reviewed

1. Genetic and Immunology of Brain Tumors

By Sahika Liva Cengiz and Aynur Emine Cicekcibasi


Open access peer-reviewed

2. Genetic Instability in Paediatric and Adult Brain Tumours

By Marta Viana-Pereira, Chris Jones and Rui M. Reis


Open access peer-reviewed

3. Brain Tumor Exosomes and Microvesicles: Pleiotropic Effects from Tiny Cellular Surrogates

By Michael W Graner


Open access peer-reviewed

4. Recurrent Malignant Primary Brain Tumor: the Pathophysiology and Management

By Victor Tse and Harish Babu


Open access peer-reviewed

5. The Role of Sox Transcription Factors in Brain Tumourigenesis

By Maria Ferletta


Open access peer-reviewed

6. Angiogenesis of Primary Brain Tumors: The Role of Endoglin (CD105)

By Yasuo Sugita


Open access peer-reviewed

7. The Role of Aquaporines in Brain Tumors

By Tatsuo Sawada


Open access peer-reviewed

8. Glioma Stem Cells

By Kouichi Tabu, Tetsuya Taga and Shinya Tanaka


Open access peer-reviewed

9. Molecular Hallmarks of Gliomas

By Marta Pojo and Bruno Marques Costa


Open access peer-reviewed

10. Integrated Network Analysis of Genetic and Epigenetic Factors in Glioblastoma Multiform

By Hua Dong and MomiaoXiong


Open access peer-reviewed

11. The Neural Extracellular Matrix, Cell Adhesion Molecules and Proteolysis in Glioma Invasion and Tumorigenicity

By Chrissa A. Dwyer and Russell T. Matthews


Open access peer-reviewed

12. Portrait of Transcriptional Expression Profiles Displayed by Different Glioblastoma Cell Lines

By Paulo R. D. V. Godoy, Stephano S. Mello, Daniele A. Magalhães, Flavia S. Donaires, Ana P. Lima-Montaldi, Patricia Nicolucci, Eduardo A. Donadi, Geraldo A. S. Passos and Elza T. Sakamoto-Hojo


Open access peer-reviewed

13. Genetics and Biology of Glioblastoma Multiforme

By Anália Carmo, Inês Crespo and Maria Celeste Lopes


Open access peer-reviewed

14. Chemokines in Glioma Progression

By Marco Locatelli and Alberto Mantovani


Open access peer-reviewed

15. Biomarkers of Glioma

By Shufang Liang and Guobo Shen


Open access peer-reviewed

16. MicroRNA (miRNA) Regulation in Glioma: Implications in Development, Progression, Grading, Prognosis and Therapy

By Kumaravel Somasundaram, Soumya Alige Mahabala Rao and Zahid Nawaz


Open access peer-reviewed

17. MicroRNA in Human Gliomas

By Alfredo Conti, Lucia Merlo, Domenico La Torre and M’Hammed Aguennouz


Open access peer-reviewed

18. Gliomas: Role of Wnt/β-Catenin/Tcf Signaling Pathway

By Gangadhara Reddy Sareddy and Phanithi Prakash Babu


Open access peer-reviewed

19. Insulin-Like Growth Factor Binding Protein-2: A Possible Regulator of Invasive Growth in Glioblastoma

By Tsuyoshi Fukushima and Hiroaki Kataoka


Open access peer-reviewed

20. The Role of Isocitrate Dehydrogenase Mutations in Glioma Brain Tumors

By Chi-Ming Chang, Kaiming Xu and Hui-Kuo G. Shu


Open access peer-reviewed

21. The Expression of BORIS Protein in a Newly Established Primary Glioma Cell Culture Line

By Siti Zawani Mohd Ramli, Shaharum Shamsuddin, Nik Norliza Hassan, Azmi Alias, Mohd Saffari Mohd Haspani and Jafri Abdullah


Open access peer-reviewed

22. MiR-221/222 Promote the Growth of Malignant Glioma Cells by Regulating Its Target Genes

By Zhang Chunzhi, Jiang Tao, Wang Jinhuan, Cheng Jinquan, Pu Peiyu and Kang Chunsheng


Open access peer-reviewed

23. Primary Glioblastoma with Different Patterns of EGFR Amplification and the Relationship with Gene Expression Profile

By Concha Lopez-Gines, Rosario Gil-Benso, Daniel Monleon, Jose Gonzalez-Darder and Miguel Cerda-Nicolas


Open access peer-reviewed

24. Nuclear Signaling of EGFR and EGFRvIII in Glioblastoma

By Anupama E. Gururaj, Oliver Bögler and Khatri Latha


Open access peer-reviewed

25. Ap 1 in Glioblastomas

By Densie Smith and Bruce Bejcek


Open access peer-reviewed

26. The Musashi1 RNA-Binding Protein: A Critical Regulator in Glioblastoma

By Dat T. Vo, Devraj Sandhu, Jonathan A. Gelfond and Luiz O. Penalva


Open access peer-reviewed

27. The Pivotal Roles of GSK3β in Glioma Biology

By Mitsutoshi Nakada, Toshinari Minamoto, Ilya V. Pyko, Yutaka Hayashi and Jun-ichiro Hamada


Open access peer-reviewed

28. The Role of Matrix Metalloproteinases a nd Tissue Inhibitors of Metalloproteinases in the Progression of Astrocytomas

By Fábio Motta, Renata Canalle, France Yoshioka, Giovanny Pinto, Lúcia Harada, Carlotti Jurnior, Elvis Valera, Carlos Scrideli and Luiz Tone


Open access peer-reviewed

29. Medulloblastoma – Genetic Alterations

By Esther Manor and Lipa Bodner


Open access peer-reviewed

30. The Role of HGF/c-Met Pathway Signaling in Human Medulloblastoma

By Claudia Faria, Christian Smith and James Rutka


Open access peer-reviewed

31. The Impact of Redox Balance in Brain Tumors

By Pinar Atukeren


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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