Open access peer-reviewed Edited volume

Modern Tools for Genetic Engineering

Edited by Michael Kormann

University of Tübingen

Site-specific endonucleases create double-strand breaks within the genome and can be targeted to literally any genetic mutation. Together with a repair template, a correction of the defective locus becomes possible. This book offers insight into the modern tools of genome editing, their hurdles and their huge potential. A new era of in vivo genetic engineering has begun.

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Modern Tools for Genetic EngineeringEdited by Michael Kormann

Published: May 18th 2016

DOI: 10.5772/61377

ISBN: 978-953-51-2234-0

Print ISBN: 978-953-51-2392-7

Books open for chapter submissions

6788 Total Chapter Downloads

2 Crossref Citations

3 Dimensions Citations

chaptersDownloads

Open access peer-reviewed

1. Next-Generation Therapeutics: mRNA as a Novel Therapeutic Option for Single-Gene Disorders

By Tatjana Michel, Hans-Peter Wendel and Stefanie Krajewski

1355

Open access peer-reviewed

2. Gene Delivery Technologies for Efficient Genome Editing: Applications in Gene Therapy

By Francisco Martin, Sabina Sánchez-Hernández, Alejandra Gutierrez- Guerrero and Karim Benabdellah

875

Open access peer-reviewed

3. DNA Elements Tetris: A Strategy for Gene Correction

By Colette Bastie and Florence Rouleux-Bonnin

499

Open access peer-reviewed

4. Gene Correction Technology and Its Impact on Viral Research and Therapy

By Guan-Huei Lee and Myo Myint Aung

586

Open access peer-reviewed

5. Gene Editing in Adult Hematopoietic Stem Cells

By Sergio López-Manzaneda, Sara Fañanas-Baquero, Virginia Nieto- Romero, Francisco-Jose Roman-Rodríguez, Maria Fernandez-Garcia, Maria J. Pino-Barrio, Fatima Rodriguez-Fornes, Begoña Diez- Cabezas, Maria Garcia-Bravo, Susana Navarro, Oscar Quintana- Bustamante and Jose C. Segovia

899

Open access peer-reviewed

6. Insulin Gene Therapy for Type 1 Diabetes Mellitus: Unique Challenges Require Innovative Solutions

By Andrew M Handorf, Hans W Sollinger and Tausif Alam

961

Open access peer-reviewed

7. Application of Genome Editing Technology to MicroRNA Research in Mammalians

By Lei Yu, Jennifer Batara and Biao Lu

947

Open access peer-reviewed

8. Emerging Gene Correction Strategies for Muscular Dystrophies: Scientific Progress and Regulatory Impact

By Houria Bachtarzi and Tim Farries

666

Edited volume and chapters are indexed in

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  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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