Open access peer-reviewed Edited volume

Medicinal Chemistry and Drug Design

Over the recent years, medicinal chemistry has become responsible for explaining interactions of chemical molecules processes such that many scientists in the life sciences from agronomy to medicine are engaged in medicinal research. This book contains an overview focusing on the research area of enzyme inhibitors, molecular aspects of drug metabolism, organic synthesis, prodrug synthesis, in silico studies and chemical compounds used in relevant approaches. The book deals with basic issues and some of the recent developments in medicinal chemistry and drug design. Particular emphasis is devoted to both theoretical and experimental aspect of modern drug design. The primary target audience for the book includes students, researchers, biologists, chemists, chemical engineers and professionals who are interested in associated areas. The textbook is written by international scientists with expertise in chemistry, protein biochemistry, enzymology, molecular biology and genetics many of which are active in biochemical and biomedical research. We hope that the textbook will enhance the knowledge of scientists in the complexities of some medicinal approaches; it will stimulate both professionals and students to dedicate part of their future research in understanding relevant mechanisms and applications of medicinal chemistry and drug design.

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Medicinal Chemistry and Drug DesignEdited by Deniz Ekinci

Published: May 16th 2012

DOI: 10.5772/2457

ISBN: 978-953-51-0513-8

Copyright year: 2012

Books open for chapter submissions

53619 Total Chapter Downloads

2 Crossref Citations

21 Web of Science Citations

22 Dimensions Citations

chaptersDownloads

Open access peer-reviewed

1. Kojic Acid Derivatives

By Mutlu D. Aytemir and G. Karakaya

6721

Open access peer-reviewed

2. Analysis of Protein Interaction Networks to Prioritize Drug Targets of Neglected-Diseases Pathogens

By Aldo Segura-Cabrera, Carlos A. García-Pérez, Mario A. Rodríguez-Pérez, Xianwu Guo, Gildardo Rivera and Virgilio Bocanegra-García

2122

Open access peer-reviewed

3. Recent Applications of Quantitative Structure-Activity Relationships in Drug Design

By Omar Deeb

3449

Open access peer-reviewed

4. Atherosclerosis and Antihyperlipidemic Agents

By Laila Mahmoud Mohamed Gad

3551

Open access peer-reviewed

5. Inhibitors of Serine Proteinase - Application in Agriculture and Medicine

By Rinat Islamov, Tatyana Kustova and Alexander Ilin

2373

Open access peer-reviewed

6. Pyrrolobenzodiazepines as Sequence Selective DNA Binding Agents

By Ahmed Kamal, M. Kashi Reddy, Ajay Kumar Srivastava and Y. V. V. Srikanth

4156

Open access peer-reviewed

7. Regulation of EC-SOD in Hypoxic Adipocytes

By Tetsuro Kamiya, Hirokazu Hara, Naoki Inagaki and Tetsuo Adachi

1694

Open access peer-reviewed

8. Development of an Ultrasensitive CRP Latex Agglutination Reagent by Using Amino Acid Spacers

By Tomoe Komoriya, Kazuaki Yoshimune, Masahiro Ogawa, Mitsuhiko Moriyama and Hideki Kohno

3348

Open access peer-reviewed

9. Pattern Recognition Receptors Based Immune Adjuvants: Their Role and Importance in Vaccine Design

By Halmuthur M. Sampath Kumar, Irfan Hyder and Parvinder Pal Singh

2956

Open access peer-reviewed

10. Microarray Analysis in Drug Discovery and Biomarker Identification

By Yushi Liu and Joseph S. Verducci

2552

Open access peer-reviewed

11. Supraventricular Tachycardia Due to Dopamine Infused Through Epidural Catheter Accidentally (A Case Report and Review)

By Demet Coskun and Ahmet Mahli

1966

Open access peer-reviewed

12. Effective Kinetic Methods and Tools in Investigating the Mechanism of Action of Specific Hydrolases

By Emmanuel M. Papamichael, Panagiota-Yiolanda Stergiou, Athanasios Foukis, Marina Kokkinou and Leonidas G. Theodorou

2034

Open access peer-reviewed

13. Aluminium - Non-Essential Activator of Pepsin: Kinetics and Thermodynamics

By Vesna Pavelkic, Tanja Brdaric and Kristina Gopcevic

1994

Open access peer-reviewed

14. Peptides and Peptidomimetics in Medicinal Chemistry

By Paolo Ruzza

4198

Open access peer-reviewed

15. Carbonic Anhydrase Inhibitors and Activators: Small Organic Molecules as Drugs and Prodrugs

By Murat Şentürk, Hüseyin Çavdar, Oktay Talaz and Claudiu T. Supuran

2613

Open access peer-reviewed

16. Stochastic Simulation for Biochemical Reaction Networks in Infectious Disease

By Shailza Singh and Sonali Shinde

1767

Open access peer-reviewed

17. Alternative Perspectives of Enzyme Kinetic Modeling

By Ryan Walsh

3204

Open access peer-reviewed

18. Molecular Modeling and Simulation of Membrane Transport Proteins

By Andreas Jurik, Freya Klepsch and Barbara Zdrazil

2921

Edited volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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