Open access peer-reviewed Edited volume

Iron Metabolism

Iron has various functions in the body, including the metabolism of oxygen in a variety of biochemical processes. Iron, as either heme or in its "nonheme" form, plays an important role in key reactions of DNA synthesis and energy production. However, low solubility of iron in body fluids and the ability to form toxic hydroxyl radicals in presence of oxygen make iron uptake, use and storage a serious challenge. The discovery of new metal transporters, receptors and peptides and as well as the discovery of new cross-interactions between known proteins are now leading to a breakthrough in the understanding of systemic iron metabolism. The objective of this book is to review and summarize recent developments in our understanding of iron transport and storage in living systems.

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Iron MetabolismEdited by Sarika Arora

Published: June 29th 2012

DOI: 10.5772/1633

ISBN: 978-953-51-0605-0

Books open for chapter submissions

23587 Total Chapter Downloads

8 Web of Science Citations

chaptersDownloads

Open access peer-reviewed

1. Iron Metabolism in Humans: An Overview

By Sarika Arora and Raj Kumar Kapoor

9393

Open access peer-reviewed

2. Cellular Iron Metabolism – The IRP/IRE Regulatory Network

By Ricky S. Joshi, Erica Moran and Mayka Sanchez

3133

Open access peer-reviewed

3. Relationship Between Iron and Erythropoiesis

By Nadia Maria Sposi

4366

Open access peer-reviewed

4. Iron Deficiency in Hemodialysis Patients – Evaluation of a Combined Treatment with Iron Sucrose and Erythropoietin-Alpha: Predictors of Response, Efficacy and Safety

By Martin Gutierrez Martin, Maria Soledad Romero Colas, and Jose Antonio Moreno Chulilla

1526

Open access peer-reviewed

5. Role of Hepcidin in Dysregulation of Iron Metabolism and Anemia of Chronic Diseases

By Bhawna Singh, Sarika Arora, SK Gupta and Alpana Saxena

2791

Open access peer-reviewed

6. Iron Metabolism in Pathogenic Trypanosomes

By Bruno Manta, Luciana Fleitas and Marcelo Comini

2378

Edited volume and chapters are indexed in

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