Open access peer-reviewed Edited volume

Herpesviridae

Herpesviruses are unique among viruses as they encode for a complex self-regulatory system, aggressively invade and persist in the host, evade immune defense, alter all regulatory mechanisms of the macroorganism and modify the replication of heterologous viruses. Environmental factors influence these unconventional relationships. Consequently, a single herpesvirus species can be attributed to a wide range of diseases as etiological agents or cofactors. This book is intended to give an overview on selected clinical hot topics: herpes simplex virus encephalitis, persistent infection in the gingiva, thymidine kinase gene expression causing male infertility, and pharmaceutical reactivation of Epstein-Barr virus for oncolysis. Immune evasion mechanisms and new ways to formulate vaccines are exhaustively reviewed. Finally, a surprise: bovine herpesviruses could serve as models to study the pathomechanism of herpesviruses.

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HerpesviridaeEdited by Joseph Ongrádi

Published: September 7th 2016

DOI: 10.5772/61923

ISBN: 978-953-51-2611-9

Print ISBN: 978-953-51-2610-2

Books open for chapter submissions

4944 Total Chapter Downloads

2 Crossref Citations

3 Dimensions Citations

chaptersDownloads

Open access peer-reviewed

1. Introductory Chapter: Unconventional Philosophy of Herpesvirus Infections

By Joseph Ongrádi

495

Open access peer-reviewed

2. Herpes Simplex Virus Type 1 at the Central Nervous System

By Carola Otth, Francisca Acuña‐Hinrichsen, Luis Leyton, Carolina Martin and Margarita I. Concha

697

Open access peer-reviewed

3. Herpesviruses in Periapical Pathoses: An Updated Systematic Review

By Aleksandar Jakovljević, Miroslav Andrić, Aleksandra Knežević, Katarina Beljić-Ivanović, Maja Miletić, Tanja Jovanović, Ljiljana Kesić and Jelena Milašin

513

Open access peer-reviewed

4. Ectopic Expression of Human Herpesvirus 1 Thymidine Kinase Induces Male Infertility

By Mo Chen, Li‐yi Cai, Takako Kato and Yukio Kato

298

Open access peer-reviewed

5. Immune Evasion by Herpes Simplex Viruses

By Angello R. Retamal-Díaz, Eduardo Tognarelli, Alexis M. Kalergis, Susan M. Bueno and Pablo A. González

481

Open access peer-reviewed

6. Review: Biological and Pharmacological Basis of Cytolytic Viral Activation in EBV-Associated Nasopharyngeal Carcinoma

By Natalie Oker, Nikiforos-Ioannis Kapetanakis and Pierre Busson

739

Open access peer-reviewed

7. Herpes Simplex Virus 1 and 2 Vaccine Design: What can we Learn from the Past?

By Vladimíra Ďurmanová, Marian Adamkov and Július Rajčáni

652

Open access peer-reviewed

8. Herpesvirus in Bovines: Importance of Bovine Herpesvirus Type 1

By Gurpreet Kaur and Mudit Chandra

661

Open access peer-reviewed

9. Latency of Bovine Herpesvirus 1 (BoHV-1) in Sensory Neurons

By Clinton Jones

408

Edited volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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