Open access peer-reviewed Edited Volume


Edited by Joseph Ongrádi

Semmelweis University, Hungary

Herpesviruses are unique among viruses as they encode for a complex self-regulatory system, aggressively invade and persist in the host, evade immune defense, alter all regulatory mechanisms of the macroorganism and modify the replication of heterologous viruses. Environmental factors influence these unconventional relationships. Consequently, a single herpesvirus species can be attributed to a wide range of diseases as etiological agents or cofactors. This book is intended to give an overview on selected clinical hot topics: herpes simplex virus encephalitis, persistent infection in the gingiva, thymidine kinase gene expression causing male infertility, and pharmaceutical reactivation of Epstein-Barr virus for oncolysis. Immune evasion mechanisms and new ways to formulate vaccines are exhaustively reviewed. Finally, a surprise: bovine herpesviruses could serve as models to study the pathomechanism of herpesviruses.

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HerpesviridaeEdited by Joseph Ongrádi

Published: September 7th 2016

DOI: 10.5772/61923

ISBN: 978-953-51-2611-9

Print ISBN: 978-953-51-2610-2

eBook (PDF) ISBN: 978-953-51-4185-3

Copyright year: 2016

Books open for chapter submissions

10838 Total Chapter Downloads

11 Crossref Citations

12 Web of Science Citations

18 Dimensions Citations


Open access peer-reviewed

1. Introductory Chapter: Unconventional Philosophy of Herpesvirus Infections

By Joseph Ongrádi


Open access peer-reviewed

2. Herpes Simplex Virus Type 1 at the Central Nervous System

By Carola Otth, Francisca Acuña‐Hinrichsen, Luis Leyton, Carolina Martin and Margarita I. Concha


Open access peer-reviewed

3. Herpesviruses in Periapical Pathoses: An Updated Systematic Review

By Aleksandar Jakovljević, Miroslav Andrić, Aleksandra Knežević, Katarina Beljić-Ivanović, Maja Miletić, Tanja Jovanović, Ljiljana Kesić and Jelena Milašin


Open access peer-reviewed

4. Ectopic Expression of Human Herpesvirus 1 Thymidine Kinase Induces Male Infertility

By Mo Chen, Li‐yi Cai, Takako Kato and Yukio Kato


Open access peer-reviewed

5. Immune Evasion by Herpes Simplex Viruses

By Angello R. Retamal-Díaz, Eduardo Tognarelli, Alexis M. Kalergis, Susan M. Bueno and Pablo A. González


Open access peer-reviewed

6. Review: Biological and Pharmacological Basis of Cytolytic Viral Activation in EBV-Associated Nasopharyngeal Carcinoma

By Natalie Oker, Nikiforos-Ioannis Kapetanakis and Pierre Busson


Open access peer-reviewed

7. Herpes Simplex Virus 1 and 2 Vaccine Design: What can we Learn from the Past?

By Vladimíra Ďurmanová, Marian Adamkov and Július Rajčáni


Open access peer-reviewed

8. Herpesvirus in Bovines: Importance of Bovine Herpesvirus Type 1

By Gurpreet Kaur and Mudit Chandra


Open access peer-reviewed

9. Latency of Bovine Herpesvirus 1 (BoHV-1) in Sensory Neurons

By Clinton Jones


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI
  • BKCI
  • BIOSIS Previews

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