Open access peer-reviewed Edited Volume

Hepatocellular Carcinoma

Future Outlook

Edited by Ahmed Kaseb

The University of Texas MD Anderson Cancer Center, United States of America

Hepatocellular carcinoma (HCC) develops as a consequence of underlying chronic liver disease, most commonly cirrhosis. Therefore, HCC management draws on the expertise of a range of medical specialists. Many components of current novel therapeutic modalities for HCC are discussed in the current version of the book within the framework of a multidisciplinary approach with special emphasis on emerging treatment approaches and research strategies. This book is the essential clinical guide for oncologists, hepatologists, surgeons, and all physicians and researchers involved in the care of patients with HCC. I would like to thank the authors for their significant efforts in bringing this edition to life. This book is a tribute to their continued dedication to improving HCC outcome.

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Hepatocellular CarcinomaFuture OutlookEdited by Ahmed Kaseb

Published: October 23rd 2013

DOI: 10.5772/50274

ISBN: 978-953-51-1202-0

eBook (PDF) ISBN: 978-953-51-7183-6

Copyright year: 2013

Books open for chapter submissions

24420 Total Chapter Downloads

6 Crossref Citations

6 Web of Science Citations

11 Dimensions Citations


Open access peer-reviewed

1. Role of Alleles and Genotypes of Polymorphisms of IL-18 (-607 C/A; and -137 C/G), IFN-γ (+874 A/T) and TNF-α (-238 A/G and -308 A/G) and HLA-G Genes in the Susceptibility of Hepatocellular Carcinoma

By Andreza Correa Teixeira, Ana de Lourdes Candolo Martinelli and Eduardo Antonio Donadi


Open access peer-reviewed

2. Liver Transplantation for Hepatocellular Carcinoma

By Emad H. Asham, Howard Mansour and Mark Ghobrial


Open access peer-reviewed

3. Radioembolization for the Treatment of Unresectable Hepatocellular Carcinoma

By Hojjat Ahmadzadehfar, Amir Sabet and Hans Jürgen Biersack


Open access peer-reviewed

4. Image-Guided Therapies for Hepatocellular Carcinoma in Hepatocelluar Carcinoma — Future Outlook

By Bruno C. Odisio, Ravi Murthy and Michael J. Wallace


Open access peer-reviewed

5. Neoadjuvant Chemotherapy for Hepatocellular Carcinoma

By Xin-yu Huang, Qi Zheng and Zhou Yuan


Open access peer-reviewed

6. Targets and Approaches to Control Hepatocellular Carcinoma in Future

By Mukherjee Biswajit, Hossain Chowdhury Mobaswar , Bhattacharya Sanchari and Shampa Ghosh


Open access peer-reviewed

7. Early Chronic Inflammation and Subsequent Somatic Mutations Shift Phospho-Smad3 Signaling from Tumor- Suppression to Fibro-Carcinogenesis in Human Chronic Liver Diseases

By Miki Murata, Katsunori Yoshida and Koichi Matsuzaki


Open access peer-reviewed

8. Surgical Treatment Strategies and Prognosis of Hepatocellular Carcinoma

By Alessandro Uzzau, Maria Laura Pertoldeo, Vittorio Cherchi, Serena Bertozzi, Claudio Avellini and Giorgio Soardo


Open access peer-reviewed

9. Conditions that Predispose to the Development of HCC: The Role of Tumor Associated Fibroblasts and of microRNA

By C. Avellini, D. Cesselli, A.P. Beltrami, M. Orsaria, S. Marzinotto, F. Morassi and S. Uzzau


Open access peer-reviewed

10. Signs and Symptoms

By Valerio Barghini, Debora Donnini, Alessandro Uzzau and Giorgio Soardo


Open access peer-reviewed

11. Sorafenib in the Continuum of Care for Hepatocellular Carcinoma: Challenges in Defining Optimal Practice

By Ahmed O. Kaseb and Laura M. Kulik


Open access peer-reviewed

12. Sorafenib-Inhibited Signaling: Emerging Evidence of RAFIndependent Pathways as Potential Therapeutic Targets in Hepatocellular Carcinoma

By Yasunobu Matsuda, Toshifumi Wakai, Masayuki Kubota, Mami Osawa and Shun Fujimaki


Open access peer-reviewed

13. Insulin-Like Growth Factor-II: Molecular-Targeted Therapy for Hepatocellular Carcinoma

By Min Yao, Li Wang, Meijuan Yan, Xiaodi Yan and Dengfu Yao


Open access peer-reviewed

14. Simultaneous Changes in Expression of Bile Canalicular CD10 and Sinusoidal CD105 (Endoglin) in Chronic Hepatitis and Liver Cirrhosis

By Toshitsugu Nakamura


Open access peer-reviewed

15. Hepatocellular Carcinoma, Steroid Hormones and Metalloproteases

By Noemí Eiró, Belen Fernandez-Garcia, Antonio Altadill, Luis O. González and Francisco J. Vizoso


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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