Open access peer-reviewed Edited Volume

Glucose Tolerance

The progression from normal glucose tolerance (NGT) to type 2 diabetes involves intermediate stages of impaired fasting glucose (IFG) and impaired glucose tolerance (IGT), also known as prediabetes. The pathophysiology underlying the development of these glucose metabolic alterations is multifactorial, leading to an alteration in the balance between insulin sensitivity and insulin secretion. Our knowledge of the molecular basis of the signaling pathways mediating the various physiologic effects of insulin is steadily advancing. New substrates and signaling molecules have been identified and potential mechanisms involved in the pathophysiology of type 2 diabetes have been revealed. This book summarises the current state of knowledge on the pathophysiology underlying the progression from normal glucose tolerance to type 2 diabetes and therapeutic advances in the improvement of glycaemic control in prediabetic and diabetic states.

Read more >Order hardcopy
Glucose ToleranceEdited by Sureka Chackrewarthy

Published: December 12th 2012

DOI: 10.5772/2916

ISBN: 978-953-51-0891-7

eBook (PDF) ISBN: 978-953-51-7051-8

Copyright year: 2012

Books open for chapter submissions

29724 Total Chapter Downloads

25 Crossref Citations

34 Web of Science Citations

49 Dimensions Citations


Open access peer-reviewed

1. The Glucose Tolerance Test as a Laboratory Tool with Clinical Implications

By Paul Ernsberger and Richard J. Koletsky


Open access peer-reviewed

2. Can We Prevent or Delay Type 2 Diabetes?

By Merita Emini Sadiku


Open access peer-reviewed

3. Impaired Glucose Tolerance, Obesity and Inflammatory Mediators

By Ayfer Colak and Gulden Diniz


Open access peer-reviewed

4. Sex Differences in Obesity-Related Glucose Intolerance and Insulin Resistance

By Haifei Shi and Shiva Priya Dharshan Senthil Kumar


Open access peer-reviewed

5. Age is an Important Risk Factor for Type 2 Diabetes Mellitus and Cardiovascular Diseases

By Ketut Suastika, Pande Dwipayana, Made Siswadi Semadi and R.A. Tuty Kuswardhani


Open access peer-reviewed

6. Glucose Tolerance and Elders – Lessons We Have Learned and Challenges for the Future

By Sylwia Dzięgielewska-Gęsiak and Ewa Wysocka


Open access peer-reviewed

7. The Relationship Between Chronic Alcohol Use and Type 2 Diabetes Mellitus: New Insights into Mechanisms of Appetite-Regulating Peptides

By Soo-Jeong Kim and Dai-Jin Kim


Open access peer-reviewed

8. Importance of Dietary Fatty Acid Profile and Experimental Conditions in the Obese Insulin-Resistant Rodent Model of Metabolic Syndrome

By Annadie Krygsman


Open access peer-reviewed

9. Intestinal Disaccharidase Activity and Uptake of Glucose from Sucrose

By Kia Halschou Hansen, Klaus Bukhave and Jens Rikardt Andersen


Open access peer-reviewed

10. Glucose Tolerance Factor – Insulin Mimetic and Potentiating Agent – A Source for a Novel Anti Diabetic Medication

By Nitsa Mirsky


Open access peer-reviewed

11. Medicinal Plants and Natural Compounds from the Genus Morus (Moraceae) with Hypoglycemic Activity: A Review

By Jackson Roberto Guedes da Silva Almeida, Grasielly Rocha Souza, Edigênia Cavalcante da Cruz Araújo, Fabrício Souza Silva, Julianeli Tolentino de Lima, Luciano Augusto de Araújo Ribeiro, Xirley Pereira Nunes, José Maria Barbosa Filho, Lucindo José Quintans Júnior and Márcio Roberto Viana dos Santos


Open access peer-reviewed

12. Hypoglycaemic and Hypolipidaemic Effects of an Ethylacetate Fraction of Artocarpus heterophyllus Leaves

By Sureka Chackrewarthy and M.I. Thabrew


Open access peer-reviewed

13. Non-Obese Type 2 Diabetes Animals Models

By Yukihito Ishii, Takeshi Ohta and Tomohiko Sasase


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

Order a hardcopy of the Edited Volume

Free shipping with DHL Express

Hardcover (ex. VAT)£119

Order now

Residents of European Union countries need to add a Book Value-Added Tax of 5%. Institutions and companies, registered as VAT taxable entities in their own EU member state, will not pay VAT by providing IntechOpen with their VAT registration number. This is made possible by the EU reverse charge method.

Special discount for IntechOpen contributors

All IntechOpen contributors are offered special discounts starting at 40% OFF available through your personal dashboard

Login and purchase