Open access peer-reviewed Edited Volume

Glia in Health and Disease

Edited by Tania Spohr

Instituto Estadual do Cérebro Paulo Niemeyer

The book will highlight the role played by glial cells in the central and peripheral nervous systems in both healthy and unhealthy individuals. Among all processes involved, we will discuss the importance of the enteric nervous system in the control of gut homeostasis, in the interaction with the immune system, and its participation in pathological conditions such as metabolic syndrome. We will also look at the relevance of astrocytes during synaptic transmission and the regulation of plasticity by releasing gliotransmitters. Ultimately, we will highlight the influence of astrocytes during the development of a number of neurodegenerative diseases, such as multiple sclerosis and Alzheimer’s disease, focusing on how the serum levels of the astrocytic protein S100B can be used as a biomarker for clinical decisions.

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Glia in Health and DiseaseEdited by Tania Spohr

Published: May 20th 2020

DOI: 10.5772/intechopen.82593

ISBN: 978-1-78985-254-7

Print ISBN: 978-1-78985-253-0

eBook (PDF) ISBN: 978-1-78985-614-9

Copyright year: 2020

Books open for chapter submissions

3202 Total Chapter Downloads

1 Crossref Citations

4 Dimensions Citations


Open access peer-reviewed

1. Synaptic Functions of Astroglial Hemichannels

By Juan A. Orellana


Open access peer-reviewed

2. Astrocytic S100B, Blood-Brain Barrier and Neurodegenerative Diseases

By Anuradha Krishnan, Hao Wu and Venkat Venkataraman


Open access peer-reviewed

3. The Enteric Glial Network Acts in the Maintenance of Intestinal Homeostasis and in Intestinal Disorders

By Juliana de Mattos Coelho-Aguiar, Carla Pires Veríssimo, Deiziane Viana da Silva Costa, Beatriz Bastos de Moraes Thomasi, Ana Carina Bon Frauches, Fabiana Pereira Ribeiro, Ana Lucia Tavares Gomes, Gerly Anne de Castro Brito and Vivaldo Moura-Neto


Open access peer-reviewed

4. Involvement of Astrocytes in the Process of Metabolic Syndrome

By Ana Karolina Santana Nunes, Haniel Soares Fernandes and Sura Wanessa Santos Rocha


Open access peer-reviewed

5. Astrocytes and Inflammatory Processes in Alzheimer’s Disease

By Soraya L. Valles, Federico Burguet, Antonio Iradi, Martin Aldasoro, Jose M. Vila, Constanza Aldasoro and Adrián Jordá


Open access peer-reviewed

6. Astrocytes: Initiators of and Responders to Inflammation

By Allison Soung and Robyn S. Klein


Open access peer-reviewed

7. Astrocytes in Pathogenesis of Multiple Sclerosis and Potential Translation into Clinic

By Izrael Michal, Slutsky Shalom Guy and Revel Michel


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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