Open access peer-reviewed Edited volume

Genes and Autoimmunity

Intracellular Signaling and Microbiome Contribution

Autoimmune disorders are known to affect a substantial number of people worldwide, demonstrating a gender bias and are the second largest cause of chronic illness. Recently, the attention has been focused on lifestyle changes as a major factor in the rise of autoimmune disease frequency. The two sections of this book are focused on the new opportunities for moving research forward, leading to a new approach to prevention and treatment of autoimmune diseases. A better understanding of the mechanisms of gene expression and triggering signaling pathways, which is involved in autoimmune pathogenesis simultaneously with current data for the interaction of microbiota with human immune system, will help to better understand the immune imbalance implicated in autoimmunity.

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Genes and AutoimmunityIntracellular Signaling and Microbiome ContributionEdited by Spaska Stanilova

Published: March 13th 2013

DOI: 10.5772/45733

ISBN: 978-953-51-1028-6

Copyright year: 2013

Books open for chapter submissions

11468 Total Chapter Downloads

2 Crossref Citations

7 Web of Science Citations

6 Dimensions Citations

chaptersDownloads

Open access peer-reviewed

1. Genetic Susceptibility to Graves’ Ophthalmopathy

By Junichi Tani and Yuji Hiromatsu

826

Open access peer-reviewed

2. Gene Polymorphisms of Immunoregulatory Cytokines IL-10 and TGF-β1 in Systemic Lupus Erythematosus

By Irena Manolova, Mariana Ivanova and Spaska Stanilova

1044

Open access peer-reviewed

3. Toll-Like Receptor 3 and Retinoic Acid-Inducible Gene-I Implicated to the Pathogenesis of Autoimmune Renal Diseases

By Hiroshi Tanaka and Tadaatsu Imaizumi

773

Open access peer-reviewed

4. Gene Expression Pattern Characterises Development of Multiple Sclerosis

By Lotti Tajouri, Ekua W. Brenu, Kevin Ashton, Donald R. Staines and Sonya M. Marshall-Gradisnik

794

Open access peer-reviewed

5. Costimulatory Molecules in Rheumatic Diseases Revisited with an Emphasis on Their Roles in Autoimmune Sjögren’s Syndrome

By Adrienne E. Gauna and Seunghee Cha

1295

Open access peer-reviewed

6. Immune Synapses Between Lymphocytes and Target Cells in Autoimmune Thyroid Diseases

By Iwona Ben-Skowronek and Roman Ciechanek

955

Open access peer-reviewed

7. Microbiome and Autoimmunity

By Natalie Cherepahina, Zaur Shogenov, Mariya Bocharova, Murat Agirov, Jamilyia Tabaksoeva, Mikhail Paltsev and Sergey Suchkov

936

Open access peer-reviewed

8. Environmental Factors and Type 1 Diabetes Mellitus in Pediatric Age Group

By Giuseppe d'Annunzio, Andrea Accogli, Ramona Tallone, Sara Bolloli and Renata Lorini

922

Open access peer-reviewed

9. Common Mechanisms of Pathogenesis of Tissue-Specific Autoimmune Diseases: The Edited Model to Illustrate Those for IDDM and Multiple Sclerosis

By S. A. Krynskiy, A. V. Kostyakov, D. S. Kostyushev, D. A. Gnatenko and S. V. Suchkov

786

Open access peer-reviewed

10. Chronic Fatigue Syndrome/Myalgic Encephalomyelitis and Parallels with Autoimmune Disorders

By Ekua W. Brenu, Lotti Tajouri, Kevin J. Ashton, Donald R. Staines and Sonya M. Marshall-Gradisnik

1458

Open access peer-reviewed

11. Biomarkers of Inflammatory Arthritis and Proteomics

By Opeyemi S. Ademowo, Lisa Staunton, Oliver FitzGerald and Stephen R. Pennington

1679

Edited volume and chapters are indexed in

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  • CNKI

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