Open access peer-reviewed Edited Volume

Gastritis and Gastric Cancer

New Insights in Gastroprotection, Diagnosis and Treatments

This book is a comprehensive overview of invited contributions on Helicobacter pylori infection in gastritis and gastric carcinogenesis. The first part of the book covers topics related to the pathophysiology of gastric mucosal defense system and gastritis including the gastroprotective function of the mucus, the capsaicin-sensitive afferent nerves and the oxidative stress pathway involved in inflammation, apoptosis and autophagy in H. pylori related gastritis. The next chapters deal with molecular pathogenesis and treatment, which consider the role of neuroendocrine cells in gastric disease, DNA methylation in H. pylori infection, the role of antioxidants and phytotherapy in gastric disease. The final part presents the effects of cancer risk factors associated with H. pylori infection. These chapters discuss the serum pepsinogen test, K-ras mutations, cell kinetics, and H. pylori lipopolysaccharide, as well as the roles of several bacterial genes (cagA, cagT, vacA and dupA) as virulence factors in gastric cancer, and the gastrokine-1 protein in cancer progression.

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Gastritis and Gastric CancerNew Insights in Gastroprotection, Diagnosis and TreatmentsEdited by Paola Tonino

Published: September 15th 2011

DOI: 10.5772/876

ISBN: 978-953-307-375-0

eBook (PDF) ISBN: 978-953-51-6483-8

Copyright year: 2011

Books open for chapter submissions

58400 Total Chapter Downloads

8 Crossref Citations

21 Web of Science Citations

30 Dimensions Citations


Open access peer-reviewed

1. Protective Effects of Gastric Mucus

By Takafumi Ichikawa and Kazuhiko Ishihara


Open access peer-reviewed

2. Approach to Role of Capsaicin - Sensitive Afferent Nerves in the Development and Healing in Patients with Chronic Gastritis

By Gyula Mozsik, Imre L. Szabo and Andras Dömötör


Open access peer-reviewed

3. Oxidative Stress Pathway Driven by Inflammation in Gastric Mucosa

By Dovhanj Jasna and Švagelj Dražen


Open access peer-reviewed

4. Oxidative Stress Involved Autophagy and Apoptosis in Helicobacter pylori Related Gastritis

By Jyh-Chin Yang and Chiang-Ting Chien


Open access peer-reviewed

5. Chronic Gastritis

By Wojciech Kozlowski, Cezary Jochymski and Tomasz Markiewicz


Open access peer-reviewed

6. The Role of Morphometry in Diagnostic of Chronic Gastritis

By Tomasz Markiewicz, Wojciech Kozlowski and Cezary Jochymski


Open access peer-reviewed

7. Molecular Pathology of Gastritis

By Alejandro H. Corvalán, Gonzalo Carrasco and Wilda Olivares


Open access peer-reviewed

8. Role of Natural Antioxidants in Gastritis

By Mohamed M. Elseweidy


Open access peer-reviewed

9. New Approaches in Gastritis Treatment

By Guillermo Marcial, Cecilia Rodríguez, Marta Medici and Graciela Font de Valdez


Open access peer-reviewed

10. Gastric Cancer Risk Diagnosis and Prevention in Subjects with Helicobacter pylori-related Chronic Gastritis

By Shotaro Enomoto, Mika Watanabe, Chizu Mukoubayashi, Hiroshi Ohata, Hirohito Magari, Izumi Inoue, Takao Maekita, Mikitaka Iguchi, Kimihiko Yanaoka, Hideyuki Tamai, Jun Kato, Masashi Oka and Masao Ichinose


Open access peer-reviewed

11. Role of Genetic and Environmental Risk Factors in Gastric Carcinogenesis Pathway

By Bárbara Peleteiro and Nuno Lunet


Open access peer-reviewed

12. Effects of Helicobacter pylori Infection on the Histology, Cellular Phenotype, K-ras Mutations, and Cell Kinetics in Gastric Intestinal Metaplasia in Patients with Chronic Gastritis and Gastric Cancer

By Jiro Watari, Hiroki Tanabe, Kentaro Moriichi, Mikihiro Fujiya, Peter S. Amenta, Hiroto Miwa, Yutaka Kohgo and Kiron M. Das


Open access peer-reviewed

13. Helicobacter pylori Lipopolysaccharide as a Possible Pathogenic Factor for Gastric Carcinogenesis

By Shin-ichi Yokota, Ken-ichi Amano and Nobuhiro Fujii


Open access peer-reviewed

14. Virulence Factors of Helicobacter pylori and Their Relationship with the Development of Early and Advanced Distal Intestinal Type Gastric Adenocarcinoma

By Bruna Maria Roesler, Sandra Cecília Botelho Costa and José Murilo Robilotta Zeitune


Open access peer-reviewed

15. Role of Gastrokine 1 in Gastric Cancer

By Emilia Rippa, Paolo Mallardo and Paolo Arcari


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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