Open access peer-reviewed Edited Volume

Fibrinolysis and Thrombolysis

Edited by Krasimir1 Kolev

Semmelweis University, Hungary

This book familiarizes the reader with some recent trends in the theory and practice of thrombolysis. It covers the field of fibrinolysis from the standpoint of basic scientists and clinicians and delivers the state-of-the-art information on the biochemistry and pharmacology of fibrinolysis, as well as related novel methodological and diagnostic tools in the field. An introductory chapter summarizes the basic molecular mechanisms in fibrinolysis (plasminogen, its endogenous activators and their inhibitors, plasmin and its inhibitors). Recent developments in our understanding of fibrin formation are described in the context of its impact on fibrinolysis. The discussion of neutrophil extracellular traps in the modulation of fibrin assembly and the consequences regarding plasminogen activation and plasmin action addresses a novel aspect of fibrinolysis.

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Fibrinolysis and ThrombolysisEdited by Krasimir1 Kolev

Published: May 7th 2014

DOI: 10.5772/57039

ISBN: 978-953-51-1265-5

eBook (PDF) ISBN: 978-953-51-7203-1

Copyright year: 2014

Books open for chapter submissions

17256 Total Chapter Downloads

12 Crossref Citations

23 Web of Science Citations

28 Dimensions Citations


Open access peer-reviewed

1. An Insight into the Abnormal Fibrin Clots — Its Pathophysiological Roles

By Payel Bhattacharjee and Debasish Bhattacharyya


Open access peer-reviewed

2. Fibrinolysis at the Interface of Thrombosis and Inflammation — The Role of Neutrophil Extracellular Traps

By Imre Varjú and Krasimir Kolev


Open access peer-reviewed

3. S100A10: A Key Regulator of Fibrinolysis

By Alexi P. Surette and David M. Waisman


Open access peer-reviewed

4. Comparative Fibrinolysis

By Emma Beatriz Casanave and Juan Tentoni


Open access peer-reviewed

5. Thrombolytic/Fibrinolytic Mechanism of Natural Products

By Eduardo Fuentes, Luis Guzmán, Marcelo Alarcón, Rodrigo Moore and Iván Palomo


Open access peer-reviewed

6. Clinical Application of Fibrinolytic Assays

By Dominic Pepperell, Marie-Christine Morel-Kopp and Chris Ward


Open access peer-reviewed

7. Coagulation and Fibrinolysis Markers and Their Use for the Prediction of High Risk Patients with Venous Thromboembolism Following Total Hip Arthroplasty

By Yutaka Inaba, Yohei Yukizawa and Tomoyuki Saito


Open access peer-reviewed

8. Thrombolysis or Operation: That is the Question in Prosthetic Valve Thrombosis

By Giuseppe Filiberto Serraino, Roberto Lorusso and Attilio Renzulli


Open access peer-reviewed

9. Coagulation and Fibrinolysis Abnormalities in Patients with Muscular Dystrophy

By Toshio Saito


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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