Open access peer-reviewed Edited Volume

Alzheimer's Disease Pathogenesis - Core Concepts, Shifting Paradigms and Therapeutic Targets

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Academic Editor

Suzanne De La Monte
Suzanne De La Monte

Brown University,
United States of America

Published12 September 2011

Doi10.5772/951

ISBN978-953-307-690-4

eBook (PDF) ISBN978-953-51-4437-3

Copyright year2011

Number of pages704

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Indexed in the Book Citation Index (BKCI) in Web of Science Core Collection™

Edited Volume and chapters are indexed in

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  • Crossref
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Table of Contents

Open access  chapters

1. Alzheimer ́s Disease – The New Actors of an Old Drama

By Mario Álvarez Sánchez, Carlos A. Sánchez Catasús, Ivonne Pedroso Ibañez, Maria L. Bringas and Arnoldo Padrón Sánchez

2,134
2. Pathophysiology of Late Onset Alzheimer Disease

By Ahmet Turan Isik and M. Refik Mas

2,437
3. Expression and Cerebral Function of Amyloid Precursor Protein After Rat Traumatic Brain Injury

By Tatsuki Itoh, Motohiro Imano, Shozo Nishida, Masahiro Tsubaki, Shigeo Hashimoto, Akihiko Ito and Takao Satou

2,584
4. Key Enzymes and Proteins in Amyloid-Beta Production and Clearance

By Cecília R A Santos, Isabel Cardoso and Isabel Gonçalves

2,888
1
5. Transporters in the Blood-Brain Barrier

By Masaki Ueno, Toshitaka Nakagawa and Haruhiko Sakamoto

3,090
7. Pathological Stages of Abnormally Processed Tau Protein During Its Aggregation into Fibrillary Structures in Alzheimer’s Disease

By Francisco García-Sierra, Gustavo Basurto-Islas, Jaime Jarero-Basulto, Hugo C. Monroy-Ramírez, Francisco M. Torres Cruz, Hernán Cortés Callejas, Héctor M. Camarillo Rojas, Zdena Kristofikova, Daniela Ripova, José Luna-Muñoz, Raúl Mena, Lester I. Binder and Siddhartha Mondragón-Rodríguez

2,235
1
11. Pin1: A New Enzyme Pivotal for Protecting Against Alzheimer’s Disease

By Kazuhiro Nakamura, Suk Ling Ma and Kun Ping Lu

1,828
13. Advances in MicroRNAs and Alzheimer’s Disease Research

By Francesca Ruberti, Silvia Pezzola and Christian Barbato

3,117
1
14. Role of Mitochondria in Alzheimer ́s Disease

By Genaro Genaro Gabriel Ortiz, Fermín Pacheco-Moisés, José de Jesús García-Trejo, Roció E. González-Castañeda, Miguel A. Macías-Islas, José A. Cruz-Ramos, Irma E. Velázquez-Brizuela, Elva D. Árias Merino and Alfredo Célis de la Rosa

3,097
2,660
18. Alzheimer’s Disease and Metal Contamination: Aspects on Genotoxicity

By P.D.L. Lima, M.C. Vasconcellos, R.C. Montenegro and R.R. Burbano

4,499
19. Glucose Metabolism and Insulin Action in Alzheimer’s Disease Pathogenesis

By Domenico Bosco, Massimiliano Plastino, Antonio Spanò, Caterina Ermio and Antonietta Fava

2,965
22. Hypotension in Subcortical Vascular Dementia, a New Risk Factor – Wasn’t It Hypertension?

By Rita Moretti, Francesca Esposito, Paola Torre, Rodolfo M. Antonello and Giuseppe Bellini

2,186
23. Autophagy-Derived Alzheimer’s Pathogenesis

By Daijun Ling and Paul M. Salvaterra

2,920
1
24. Plasmalogen Deficit: A New and Testable Hypothesis for the Etiology of Alzheimer’s Disease

By Paul L. Wood, M. Amin Khan, Rishikesh Mankidy, Tara Smith and Dayan B. Goodenowe

2,806
4
25. Gangliosides as a Double-Edged Swordin Neurodegenerative Disease

By Akio Sekigawa, Masayo Fujita, Kazunari Sekiyama, Yoshiki Takamatsu, Jianshe Wei and Makoto Hashimoto

2,533
2

IMPACT OF THIS BOOK AND ITS CHAPTERS

79,535 Total Chapter Downloads

3,400 Total Chapter Views

23 Crossref Citations

46 Web of Science Citations

64 Dimensions Citations

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