Biochemistry, Genetics and Molecular Biology

Affinity Chromatography

Edited by Sameh Magdeldin, ISBN 978-953-51-0325-7, 356 pages, Publisher: InTech, Chapters published March 21, 2012 under CC BY 3.0 license
DOI: 10.5772/1959
Edited Volume

Most will agree that one major achievement in the bio-separation techniques is affinity chromatography. This coined terminology covers a myriad of separation approaches that relies mainly on reversible adsorption of biomolecules through biospecific interactions on the ligand. Within this book, the authors tried to deliver for you simplified fundamentals of affinity chromatography together with exemplarily applications of this versatile technique. We have always been endeavor to keep the contents of the book crisp and easily comprehensive, hoping that this book will receive an overwhelming interest, deliver benefits and valuable information to the readers.

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Dr. Sameh Magdeldin

Niigata University, Japan

Sameh Magdeldin is senior researcher in the Medical School, Niigata University, Japan, and academic associate professor in the Physiology Department, Suez Canal University (SCU), Egypt. He received his M.V.Sc. and Ph.D. in Physiology and his second Ph.D. in Proteomics in July 2012. He has expertise in shotgun proteomics analysis, reversed-phase chromatography and label-free comparative proteomics approaches. Dr. Magdeldin has published outstanding articles on aquaporin research using proteomics technology. He also created the outstanding “All and None” methodology for analyzing large-throughput proteomics data published in a highly respected proteomics journal. He currently serves as a guest editor, associate editor and peer reviewer for several international journals. Dr. Magdeldin received several grants and awards, such as the national encouraging prize, 8th HUPO congress young investigator award, JSN award, grant-in-aid for young scientists and young researcher overseas grant from the Japan Society for the Promotion of Science (JSPS).

Fields of Research

Experience

Education

  • 2007 - current

    Medical school, Niigata University, Niigata

    Structural pathology

  • 1999 – 2005

    SCU, SCU, Ismailia

    Physiology

  • 2007 – 2011

    Medical school, Institute of Nephrology, Niigata

    Structural pathology

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  • State of the Art of Therapeutic Endocrinology

    During the last two decades, evidence of increasing trends of several endocrine-related disorders has been strengthened. These disorders often come with lack of uniform diagnosis and/ or even unclear endocrine disruption. The later is mainly due to abnormal classical changes in the blood- released hormone to its targeted organ, abnormal communication between cells within a tissue or organ (paracrine), within the same cell (intracrine) or signals which act on the same cell (autocrine). This challenging status drives endocrinologists to the urgent need to address enormous knowledge gaps in this wide field of research (Endocrinology). From the perspective point of view that "hormones control our bodies", we need to get these hormones rebalanced so we can restore overall health. That is simply endocrinology!

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  • Gel Electrophoresis - Advanced Techniques

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  • Affinity Chromatography

    Most will agree that one major achievement in the bio-separation techniques is affinity chromatography. This coined terminology covers a myriad of separation approaches that relies mainly on reversible adsorption of biomolecules through biospecific interactions on the ligand. Within this book, the authors tried to deliver for you simplified fundamentals of affinity chromatography together with exemplarily applications of this versatile technique. We have always been endeavor to keep the contents of the book crisp and easily comprehensive, hoping that this book will receive an overwhelming interest, deliver benefits and valuable information to the readers.

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