Open access peer-reviewed Edited Volume

Drug Repurposing

Hypothesis, Molecular Aspects and Therapeutic Applications

Edited by Farid A. Badria

Mansoura University

Drug repurposing or drug repositioning is a new approach to presenting new indications for common commercial and clinically approved existing drugs. For example, chloroquine, an old antimalarial drug, showed promising results for treating COVID-19, interfering with MDR in several types of cancer, and chemosensitizing human leukemic cells.This book focuses on the hypothesis, risk/benefits, and economic impacts of drug repurposing on drug discovery in dermatology, infectious diseases, neurological disorders, cancer, and orphan diseases. It brings together up-to-date research to provide readers with an informative, illustrative, and easy-to-read book useful for students, clinicians, and the pharmaceutical industry.

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Drug RepurposingHypothesis, Molecular Aspects and Therapeutic ApplicationsEdited by Farid A. Badria

Published: December 2nd 2020

DOI: 10.5772/intechopen.83082

ISBN: 978-1-83968-521-7

Print ISBN: 978-1-83968-520-0

eBook (PDF) ISBN: 978-1-83968-522-4

Copyright year: 2020

Books open for chapter submissions

1958 Total Chapter Downloads

3 Crossref Citations

4 Dimensions Citations

chaptersDownloads

Open access peer-reviewed

1. Drug Repurposing (DR): An Emerging Approach in Drug Discovery

By Mithun Rudrapal, Shubham J. Khairnar and Anil G. Jadhav

528

Open access peer-reviewed

2. Risk-Benefit Events Associated with the Use of Aspirin for Primary Prevention of Cardiovascular Disorders

By Deepak Kumar Dash, Vishal Jain, Anil Kumar Sahu, Rajnikant Panik and Vaibhav Tripathi

67

Open access peer-reviewed

3. Drug Repurposing in Dermatology: Molecular Biology and Omics Approach

By Farid A. Badria and Abdullah A. Elgazar

145

Open access peer-reviewed

4. Drug Repurposing and Orphan Disease Therapeutics

By Neha Dhir, Ashish Jain, Dhruv Mahendru, Ajay Prakash and Bikash Medhi

279

Open access peer-reviewed

5. Drug Repurposing in Neurological Diseases: Opportunities and Challenges

By Xiao-Yuan Mao

153

Open access peer-reviewed

6. Drugs Repurposing for Multi-Drug Resistant Bacterial Infections

By Andrea Vila Domínguez, Manuel Enrique Jiménez Mejías and Younes Smani

121

Open access peer-reviewed

7. Drug Repurposing in Oncotherapeutics

By Alkeshkumar Patel

75

Open access peer-reviewed

8. Drug Repositioning for the Treatment of Glioma: Current State and Future Perspective

By Sho Tamai, Nozomi Hirai, Shabierjiang Jiapaer, Takuya Furuta and Mitsutoshi Nakada

156

Open access peer-reviewed

9. Repurposing Infectious Pathogen Vaccines in Cancer Immunotherapy

By Matteo Conti

119

Open access peer-reviewed

10. Salicylic Acid Sans Aspirin in Animals and Man

By James Ronald Lawrence, Gwendoline Joan Baxter and John Robert Paterson

135

Open access peer-reviewed

11. Repurposing Fumaric Acid Esters to Treat Conditions of Oxidative Stress and Inflammation: A Promising Emerging Approach with Broad Potential

By Ravirajsinh N. Jadeja, Folami L. Powell and Pamela M. Martin

180

Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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