Open access peer-reviewed Edited Volume

Cytotoxicity

Definition, Identification, and Cytotoxic Compounds

Edited by Erman Salih Istifli

Çukurova University

Co-editor:

Hasan Basri İla

Cukurova University

Compensating for cytotoxicity in the multicellular organism by a certain level of cellular proliferation is the primary aim of homeostasis. In addition, the loss of cellular proliferation control (tumorigenesis) is at least as important as cytotoxicity, however, it is a contrasting trauma. With the disruption of the delicate balance between cytotoxicity and proliferation, confrontation with cancer can inevitably occur. This book presents important information pertaining to the molecular control of the mechanisms of cytotoxicity and cellular proliferation as they relate to cancer. It is designed for students and researchers studying cytotoxicity and its control.

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CytotoxicityDefinition, Identification, and Cytotoxic CompoundsEdited by Erman Salih Istifli

Published: October 2nd 2019

DOI: 10.5772/intechopen.77899

ISBN: 978-1-78984-755-0

Print ISBN: 978-1-78984-754-3

eBook (PDF) ISBN: 978-1-83962-286-1

Copyright year: 2019

Books open for chapter submissions

603 Total Chapter Downloads

chaptersDownloads

Open access peer-reviewed

1. In Vitro Cytotoxicity Screening as a Criterion for the Rational Selection of Tear Substitutes

By Olga I. Aleksandrova, Igor N. Okolov, Julia I. Khorolskaya, Natalia A. Mikhailova, Diana M. Darvish and Miralda I. Blinova

133

Open access peer-reviewed

2. Study of the Cytotoxic Activity of Haarlem Oil on Different Cell Lines and a Higher Organism, Steinernema feltiae

By Khairan Khairan, Torsten Burkholz, Mareike Kelkel, Vincent Jamier, Karl-Herbert Schäfer and Claus Jacob

96

Open access peer-reviewed

3. Cytotoxic Activity of Essential Oils of Some Species from Lamiaceae Family

By Cuauhtémoc Pérez-González, Julia Pérez-Ramos, Carlos Alberto Méndez-Cuesta, Roberto Serrano-Vega, Miguel Martell-Mendoza and Salud Pérez-Gutiérrez

95

Open access peer-reviewed

4. Cytotoxic Effect and Mechanisms from Some Plant-Derived Compounds in Breast Cancer

By Elvia Pérez-Soto, Cynthia Carolina Estanislao-Gómez, David Guillermo Pérez-Ishiwara, Crisalde Ramirez-Celis and María del Consuelo Gómez-García

90

Open access peer-reviewed

5. Apoptotic Inhibitors as Therapeutic Targets for Cell Survival

By El-Shimaa Mohamed Naguib Abdelhafez, Sara Mohamed Naguib Abdelhafez Ali, Mohamed Ramadan Eisa Hassan and Adel Mohammed Abdel-Hakem

92

Open access peer-reviewed

6. Cell Division, Cytotoxicity, and the Assays Used in the Detection of Cytotoxicity

By Erman Salih Istifli, Mehmet Tahir Hüsunet and Hasan Basri Ila

104

Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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