Open access peer-reviewed Edited volume

Clostridium Difficile

A Comprehensive Overview

Clostridium difficile bacteria could be found everywhere around us: in the air, water, and soil and in the feces of humans and animals. You can easily become infected with C. difficile if you touch contaminated clothing, sheets, or other objects and then touch your mouth. Many people have the bacteria in their intestines and never have any symptoms. Still, it can cause symptoms ranging from diarrhea to life-threatening inflammation of the colon. The chance of developing a C. difficile infection increases with the usage of high doses of antibiotics over a prolonged period; thus, it is most often spread in the healthcare facilities between workers, patients, and residents. Each year in the United States, almost a half million people get sick from C. difficile, and approximately 29,000 patients died within 30 days of its initial diagnosis. Nowadays, C. difficile infections have become more frequent, severe, and difficult to treat. Therefore, the early diagnosis and the suitable treatment have become a real demand. In this book, we present the experience of worldwide specialists on the diagnosis and the treatment of C. difficile infections along with its lights and shadows.

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Clostridium DifficileA Comprehensive OverviewEdited by Shymaa Enany

Published: September 27th 2017

DOI: 10.5772/65578

ISBN: 978-953-51-3428-2

Print ISBN: 978-953-51-3427-5

Books open for chapter submissions

1750 Total Chapter Downloads

chaptersDownloads

Open access peer-reviewed

1. Introductory Chapter: Clostridium difficile Infection Overview

By Shymaa Enany

239

Open access peer-reviewed

2. Overview of Clostridium difficile Infection: Life Cycle, Epidemiology, Antimicrobial Resistance and Treatment

By Joana Isidro, Aristides L. Mendes, Mónica Serrano, Adriano O. Henriques and Mónica Oleastro

437

Open access peer-reviewed

3. Clostridium difficile Infection: Pathogenesis, Diagnosis and Treatment

By Laura Fernández-García, Lucia Blasco, María López and Maria Tomás

266

Open access peer-reviewed

4. Clostridium difficile Infection Diagnosis by Biological Molecular Methods

By Luminiţa Smaranda Iancu, Andrei Florin Cârlan and Ramona Gabriela Ursu

314

Open access peer-reviewed

5. Assays for Measuring C. difficile Toxin Activity and Inhibition in Mammalian Cells

By Mary Ann Cox, Lorraine D. Hernandez, Pulkit Gupta, Zuo Zhang, Fred Racine and Alex G. Therien

244

Open access peer-reviewed

6. Clostridium difficile in the ICU

By William C. Sherman, Chris Lewis, Jong O. Lee and David N. Herndon

250

Edited volume and chapters are indexed in

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  • AZ ebsco
  • Base
  • CNKI

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