Open access peer-reviewed Edited Volume

Challenges in Parkinson's Disease

Co-editor:

Wojciech Kozubski

Poznan University of Medical Sciences, Poland

Parkinson's disease is a common neurological disease and affects 2% population of more than 65 years of age and 5% more than 85 years of age. Pathomechanism of this disease is still not fully understood. This book is a sum up of knowledge on the genetic factors and neuronal death mechanisms induced by excitotoxic and inflammatory agents. The authors summarize the pathophysiology observed both in patients with Parkinson's disease and in experimental models. The book also contains the latest views on drug therapy used in the treatment of parkinsonism and other therapeutic approaches for Parkinson's disease. The book ''Challenges in Parkinson's Disease'' was made as a compendium on contemporary challenges in Parkinson's disease.

Read more >Order hardcopy
IntechOpen
Challenges in Parkinson's DiseaseEdited by Jolanta Dorszewska

Published: August 24th 2016

DOI: 10.5772/61880

ISBN: 978-953-51-2464-1

Print ISBN: 978-953-51-2463-4

Copyright year: 2016

Books open for chapter submissions

14670 Total Chapter Downloads

4 Crossref Citations

10 Dimensions Citations

chaptersDownloads

Open access peer-reviewed

1. Introductory Chapter - Genetic and Biochemical Factors in Parkinson’s Disease

By Jolanta Dorszewska and Wojciech Kozubski

605

Open access peer-reviewed

2. Genetics of Parkinson’s Disease: The Role of Copy Number Variations

By Valentina La Cognata, Velia D’Agata, Francesca Cavalcanti and Sebastiano Cavallaro

794

Open access peer-reviewed

3. Mechanisms for Neuronal Cell Death in Parkinson’s Disease: Pathological Cross Talks Between Epigenetics and Various Signalling Pathways

By S Meenalochani, ST Dheen and SSW Tay

631

Open access peer-reviewed

4. Inflammation: Role in Parkinson's Disease and Target for Therapy

By Patrick Flood, Naik Arbabzada and Monika Sharma

722

Open access peer-reviewed

5. Chronic Inflammation Connects the Development of Parkinson’s Disease and Cancer

By Zhiming Li and Chi-Meng Tzeng

742

Open access peer-reviewed

6. Is Chronic Systemic Inflammation a Determinant Factor in Developing Parkinson’s Disease?

By Perla Ugalde-Muñiz, Jesús Pérez-H and Anahí Chavarría

794

Open access peer-reviewed

7. Disorders of Sleep and Motor Control During the Impaired Cholinergic Innervation in Rat – Relevance to Parkinson’s Disease

By Jasna Saponjic, Jelena Petrovic, Jelena Ciric and Katarina Lazic

500

Open access peer-reviewed

8. Cognitive Impairment in Parkinson’s Disease: Historical Review, Past, and Present

By Ivan Galtier, Antonieta Nieto and Jose Barroso

552

Open access peer-reviewed

9. Brain Network Metabolic Changes in Patients with Parkinsonian Tremors

By Hideo Mure, David Eidelberg and Satoshi Goto

662

Open access peer-reviewed

10. Animal Models of Parkinson’s Disease

By Javier Blesa, Ines Trigo‐Damas, Ana Quiroga‐Varela and Natalia Lopez‐Gonzalez del Rey

1567

Open access peer-reviewed

11. Understanding Pathophysiology of Sporadic Parkinson's Disease in Drosophila Model: Potential Opportunities and Notable Limitations

By Priyanka Modi, Ayajuddin Mohamad, Limamanen Phom, Zevelou Koza, Abhik Das, Rahul Chaurasia, Saikat Samadder, Bovito Achumi, Muralidhara, Rajesh Singh Pukhrambam and Sarat Chandra Yenisetti

612

Open access peer-reviewed

12. Pharmacotherapeutic Challenges in Parkinson’s Disease Inpatients

By Unax Lertxundi, Rafael Hernández, Saioa Domingo-Echaburu, Javier Peral-Aguirregoitia and Juan Medrano

721

Open access peer-reviewed

13. Clinical and Experimental Cell Therapy in Parkinson’s Disease

By Keun-A Chang and Seonghan Kim

608

Open access peer-reviewed

14. Cell-Based Therapies for Parkinson’s Disease: Preclinical and Clinical Perspectives

By Andrea R. Di Sebastiano, Michael D. Staudt, Simon M. Benoit, Hu Xu, Matthew O. Hebb and Susanne Schmid

635

Open access peer-reviewed

15. Stem Cell Therapy for Parkinson's Disease

By Fabin Han

695

Open access peer-reviewed

16. Surgical Therapy of Parkinson's Disease

By Massimo Piacentino, Giacomo Beggio and Lorenzo Volpin

671

Open access peer-reviewed

17. Neuro-Ophthalmologic Evaluation as a Biomarker for Diagnosis and Progression in Parkinson Disease

By María Satue, Vicente Polo, Sofía Otin, Jose M. Larrosa, Javier Obis and Elena Garcia-Martin

751

Open access peer-reviewed

18. Possible Treatments of Atypical Parkinsonism

By Moretti Davide Vito

849

Open access peer-reviewed

19. The Role of Nurses in Parkinson's Disease

By Michelle Hyczy de Siqueira Tosin and Beatriz Guitton Renaud Baptista de Oliveira

1559

Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

Order a hardcopy of the Edited Volume

Free shipping with DHL Express

Hardcover (ex. VAT)£170

Order now

Residents of European Union countries need to add a Book Value-Added Tax of 5%. Institutions and companies, registered as VAT taxable entities in their own EU member state, will not pay VAT by providing IntechOpen with their VAT registration number. This is made possible by the EU reverse charge method.

Special discount for IntechOpen contributors

All IntechOpen contributors are offered special discounts starting at 40% OFF available through your personal dashboard

Login and purchase