Open access peer-reviewed Edited volume

Chagas Disease

Basic Investigations and Challenges

Edited by Veeranoot Nissapatorn

Walailak University, Thailand

Co-editor:

Helieh S. Oz

niversity of Kentucky Medical Center, United States.

This book contains 11 chapters of significant and updated materials on what we know and what we lack and need in better understanding of Trypanosoma cruzi - a parasite that never dies - and the consequences of Chagas disease as one of the most important neglected parasitic diseases threatening the global health and wellbeing. This book is intended to increase the readers' enthusiasm to explore the four sections of the contents: Section 1 begins with biochemistry, pathophysiology, histo-immunological study, and findings to assist in the diagnosis; Section 2 further investigates the role of vector in propagation of the parasite, the intensity on epidemiology, and the severity on clinical aspects, which help us to be well perceived on the course of disease; Section 3 is seeking beyond modern medicine and what lays in the nature that helps fight against this parasite; and the last section, Section 4, deals with the impacts of public health problem and the control strategies on Chagas disease.

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Chagas DiseaseBasic Investigations and ChallengesEdited by Veeranoot Nissapatorn

Published: September 12th 2018

DOI: 10.5772/intechopen.69020

ISBN: 978-1-78923-659-0

Print ISBN: 978-1-78923-658-3

Copyright year: 2018

Books open for chapter submissions

144 Total Chapter Downloads

chaptersDownloads

Open access peer-reviewed

1. Introductory Chapter: Chagas Disease and Its Global Impacts

By Frederick R. Masangkay, Giovanni DJ Milanez, Helieh S. Oz and Veeranoot Nissapatorn

14

Open access peer-reviewed

2. Biochemical, Cellular, and Immunologic Aspects during Early Interaction between Trypanosoma cruzi and Host Cell

By Rosa Lidia Solís-Oviedo, Víctor Monteon, Ruth López and Ángel de la Cruz Pech-Canul

12

Open access peer-reviewed

3. Antiparasitic Mechanisms of the Human Placenta

By Castillo Christian, Ana Liempi, Lisvaneth Medina, Ileana Carrillo and Ulrike Kemmerling

14

Open access peer-reviewed

4. The Mouse Model as a Tool for Histological, Immunological and Parasitological Studies of Trypanosoma cruzi Infection

By María Elena Villagran-Herrera, José Alejandro Martínez-Ibarra, Manuel Sánchez-Moreno, Hebert Luis Hernández-Montiel, Ricardo Francisco Mercado-Curiel, Nicolás Camacho-Calderón and José Antonio de Diego-Cabrera

11

Open access peer-reviewed

5. Transmitter Insect of Chagas Disease in Northwest Mexico: A Comparative Study of the Cuticular Hydrocarbons Profile of Three Populations of Triatoma rubida: Peridomestic, Domestic and Sylvatic

By Edgar Alfonso Paredes González, Gerardo Álvarez Hernandez and Jesús Ortega-García

11

Open access peer-reviewed

6. Eco-Epidemiology of Chagas Disease in Chile

By Mauricio Canals Lambarri, Andrea Canals Cifuentes, Salvador Ayala, Valentina Tapia-Garay and Dante Cáceres Lillo

12

Open access peer-reviewed

7. Chagas Cardiomyopathy: Role of Sustained Host-Parasite Interaction in Systemic Inflammatory Burden

By Rodolfo A Kölliker-Frers, Matilde Otero-Losada, Gabriela Razzitte, Mariela Calvo, Justo Carbajales and Francisco Capani

16

Open access peer-reviewed

8. Efficacy and Safety of Chagas Disease Drug Therapy and Treatment Perspectives

By Wilton H. Kawaguchi, Leticia Bonancio Cerqueira, Mariana Millan Fachi, Michel L. Campos, Iara J. Messias Reason and Roberto Pontarolo

16

Open access peer-reviewed

9. New Approaches for Chagas’ Disease Chemotherapy

By Guadalupe García Liñares

15

Open access peer-reviewed

10. Slowed Development of Natural Products for Chagas Disease, how to Move Forward?

By Javier Varela, Hugo Cerecetto and Mercedes González

11

Open access peer-reviewed

11. Silent Information Regulator 2 from Trypanosoma cruzi Is a Potential Target to Infection Control

By Luís Gaspar, Terry K. Smith, Nilmar Silvio Moretti, Sergio Schenkman and Anabela Cordeiro-da-Silva

12

Edited volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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