Open access peer-reviewed Edited Volume

Cancer Metastasis

Edited by Yasemin Basbinar

Dokuz Eylül University


Gizem Calibasi Kocal

Dokuz Eylül University

Metastasis of cancer cells from primary tumor site to secondary locations is considered a late event in multistep tumorigenesis, and causes most cancer-related mortality. The process from the spreading of cancer cells to the seeding of newly formed tumor colonizations is governed by sequential events, including local invasion, intravasation into stroma and blood vessels, survival in circulation, extravasation, and colonization at secondary tumor sites. Cancer research provides information on the fate of metastatic cancer cells in each sequential movement or heterogeneous tumor microenvironment. However, the complexity of this mechanism remains the most stringent concept of cancer management. This book provides information for cancer researchers on metastatic phenotypes of cancer cells, and diverse promoting factors and molecular mechanisms of metastasis.

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Cancer MetastasisEdited by Yasemin Basbinar

Published: December 5th 2018

DOI: 10.5772/intechopen.74633

ISBN: 978-1-78984-633-1

Print ISBN: 978-1-78984-632-4

eBook (PDF) ISBN: 978-1-83881-801-2

Copyright year: 2018

Books open for chapter submissions

5723 Total Chapter Downloads

1 Crossref Citations

2 Web of Science Citations

6 Dimensions Citations


Open access peer-reviewed

1. Introductory Chapter: Cancer Metastasis

By Gizem Calibasi-Kocal and Yasemin Basbinar


Open access peer-reviewed

2. Epithelial-Mesenchymal Transition in Tumor Microenvironment Induced by Hypoxia

By Görkem Eskiizmir and Erdoğan Özgür


Open access peer-reviewed

3. Tumour Microenvironment and Metastasis

By Ke Wang


Open access peer-reviewed

4. The Landscape of Histone Modification in Cancer Metastasis

By Zhaoping Qiu, Jianlin Wang and Yadi Wu


Open access peer-reviewed

5. Early Metastasis in Colorectal Cancer Poses an Option for New Diagnostic and Treatment Strategies

By Hassan Adwan, Dina Elharouni, Danira Habashy, Nadine Banna, Rania Georges, Asim Pervaiz and Martin R. Berger


Open access peer-reviewed

6. Prognostic Biomarkers for Breast Cancer Metastasis

By Kwok Kin Lee, Wee Joo Chng and Sudhakar Jha


Open access peer-reviewed

7. Ovarian Clear Cell Carcinoma: Metastatic Pathways

By Chrisostomos Sofoudis


Open access peer-reviewed

8. Genetic Mutations and Ubiquitination in Melanoma Growth and Metastasis

By Anushka Dikshit and Jennifer Zhang


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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