Calcific Aortic Valve Disease

Elena Aikawa

doi:10.5772/46239

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Open access peer-reviewed Edited Volume

Calcific Aortic Valve Disease

Edited by Elena Aikawa

Brigham and Women's Hospital, Harvard Medical School

Due to population aging, calcific aortic valve disease (CAVD) has become the most common heart valve disease in Western countries. No therapies exist to slow this disease progression, and surgical valve replacement is the only effective treatment. Calcific Aortic Valve Disease covers the contemporary understanding of basic valve biology and the mechanisms of CAVD, provides novel insights into the genetics, proteomics, and metabolomics of CAVD, depicts new strategies in heart valve tissue engineering and regenerative medicine, and explores current treatment approaches. As we are on the verge of understanding the mechanisms of CAVD, we hope that this book will enable readers to comprehend our current knowledge and focus on the possibility of preventing disease progression in the future.

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Calcific Aortic Valve DiseaseEdited by Elena Aikawa

Published: June 12th 2013

DOI: 10.5772/46239

ISBN: 978-953-51-1150-4

Books open for chapter submissions

31603 Total Chapter Downloads

11 Crossref Citations

23 Web of Science Citations

40 Dimensions Citations

chapters		Downloads
Open access peer-reviewed 1. Extracellular Matrix Organization, Structure, and Function By Dena Wiltz, C. Alexander Arevalos, Liezl R. Balaoing, Alicia A. Blancas, Matthew C. Sapp, Xing Zhang and K. Jane Grande-Allen		1735
Open access peer-reviewed 2. Anatomy and Function of Normal Aortic Valvular Complex By Ioan Tilea, Horatiu Suciu, Brindusa Tilea, Cristina Maria Tatar, Mihaela Ispas and Razvan Constantin Serban		3214
Open access peer-reviewed 3. Developmental Pathways in CAVD By Elaine E. Wirrig and Katherine E. Yutzey		1388
Open access peer-reviewed 4. Notch Signaling in Congenital and Acquired Aortic Valve Disease By Erik Fung and Masanori Aikawa		1286
Open access peer-reviewed 5. Role of MicroRNAs in Cardiovascular Calcification By Claudia Goettsch and Elena Aikawa		1516
Open access peer-reviewed 6. Proteomics and Metabolomics in Aortic Stenosis: Studying Healthy Valves for a Better Understanding of the Disease By L. Mourino-Alvarez, C.M. Laborde and M.G. Barderas		1176
Open access peer-reviewed 7. Genetics of Bicuspid Aortic Valve and Calcific Aortic Valve Disease By Robert B. Hinton		1127
Open access peer-reviewed 8. The Immune Response in In Situ Tissue Engineering of Aortic Heart Valves By S. L. M. van Loon, A. I. P. M. Smits, A. Driessen-Mol, F. P. T. Baaijens and C. V. C. Bouten		2932
Open access peer-reviewed 9. Cutting-Edge Regenerative Medicine Technologies for the Treatment of Heart Valve Calcification By Laura Iop and Gino Gerosa		2865
Open access peer-reviewed 10. Bicuspid Aortic Valve By George Tokmaji, Berto J. Bouma, Dave R. Koolbergen and Bas A.J.M. de Mol		2094
Open access peer-reviewed 11. The Bicuspid Aortic Valve By Mehmet Demir		1444
Open access peer-reviewed 12. Surgical Valve Replacement (Bioprosthetic vs. Mechanical) By Stamenko Šušak, Lazar Velicki, Dušan Popović and Ivana Burazor		1576
Open access peer-reviewed 13. Current Treatment Options in Aortic Stenosis By Fahrettin Oz, Fatih Tufan, Ahmet Ekmekci, Omer A. Sayın and Huseyin Oflaz		1730
Open access peer-reviewed 14. Stentless Bioprostheses for Aortic Valve Replacement in Calcific Aortic Stenosis By Kaan Kirali		2053
Open access peer-reviewed 15. New Therapeutic Approaches to Conventional Surgery for Aortic Stenosis in High-Risk Patients By Omer Leal, Juan Bustamante, Sergio Cánovas and Ángel G. Pinto		1280
Open access peer-reviewed 16. Indications for Transcatheter Aortic Valve Implantation By Ibrahim Akin, Stephan Kische, Henrik Schneider, Tim C. Rehders, Christoph A. Nienaber and Hüseyin Ince		1048
Open access peer-reviewed 17. Aortic Valve Replacement for Calcified Aortic Valves By Kazumasa Orihashi		2160
Open access peer-reviewed 18. Congenital Aortic Stenosis in Children By Hirofumi Saiki and Hideaki Senzaki		979

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