Calcific Aortic Valve Disease

Elena Aikawa

doi:10.5772/46239

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Open access peer-reviewed Edited Volume

Calcific Aortic Valve Disease

Edited by Elena Aikawa

Brigham and Women's Hospital, United States of America

Due to population aging, calcific aortic valve disease (CAVD) has become the most common heart valve disease in Western countries. No therapies exist to slow this disease progression, and surgical valve replacement is the only effective treatment. Calcific Aortic Valve Disease covers the contemporary understanding of basic valve biology and the mechanisms of CAVD, provides novel insights into the genetics, proteomics, and metabolomics of CAVD, depicts new strategies in heart valve tissue engineering and regenerative medicine, and explores current treatment approaches. As we are on the verge of understanding the mechanisms of CAVD, we hope that this book will enable readers to comprehend our current knowledge and focus on the possibility of preventing disease progression in the future.

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Calcific Aortic Valve DiseaseEdited by Elena Aikawa

Published: June 12th 2013

DOI: 10.5772/46239

ISBN: 978-953-51-1150-4

eBook (PDF) ISBN: 978-953-51-7163-8

Books open for chapter submissions

43430 Total Chapter Downloads

30 Crossref Citations

53 Web of Science Citations

64 Dimensions Citations

chapters		Downloads
Open access peer-reviewed 1. Extracellular Matrix Organization, Structure, and Function By Dena Wiltz, C. Alexander Arevalos, Liezl R. Balaoing, Alicia A. Blancas, Matthew C. Sapp, Xing Zhang and K. Jane Grande-Allen		2605
Open access peer-reviewed 2. Anatomy and Function of Normal Aortic Valvular Complex By Ioan Tilea, Horatiu Suciu, Brindusa Tilea, Cristina Maria Tatar, Mihaela Ispas and Razvan Constantin Serban		4334
Open access peer-reviewed 3. Developmental Pathways in CAVD By Elaine E. Wirrig and Katherine E. Yutzey		2043
Open access peer-reviewed 4. Notch Signaling in Congenital and Acquired Aortic Valve Disease By Erik Fung and Masanori Aikawa		1793
Open access peer-reviewed 5. Role of MicroRNAs in Cardiovascular Calcification By Claudia Goettsch and Elena Aikawa		2041
Open access peer-reviewed 6. Proteomics and Metabolomics in Aortic Stenosis: Studying Healthy Valves for a Better Understanding of the Disease By L. Mourino-Alvarez, C.M. Laborde and M.G. Barderas		1646
Open access peer-reviewed 7. Genetics of Bicuspid Aortic Valve and Calcific Aortic Valve Disease By Robert B. Hinton		1665
Open access peer-reviewed 8. The Immune Response in In Situ Tissue Engineering of Aortic Heart Valves By S. L. M. van Loon, A. I. P. M. Smits, A. Driessen-Mol, F. P. T. Baaijens and C. V. C. Bouten		4769
Open access peer-reviewed 9. Cutting-Edge Regenerative Medicine Technologies for the Treatment of Heart Valve Calcification By Laura Iop and Gino Gerosa		3383
Open access peer-reviewed 10. Bicuspid Aortic Valve By George Tokmaji, Berto J. Bouma, Dave R. Koolbergen and Bas A.J.M. de Mol		2686
Open access peer-reviewed 11. The Bicuspid Aortic Valve By Mehmet Demir		1892
Open access peer-reviewed 12. Surgical Valve Replacement (Bioprosthetic vs. Mechanical) By Stamenko Šušak, Lazar Velicki, Dušan Popović and Ivana Burazor		2090
Open access peer-reviewed 13. Current Treatment Options in Aortic Stenosis By Fahrettin Oz, Fatih Tufan, Ahmet Ekmekci, Omer A. Sayın and Huseyin Oflaz		2265
Open access peer-reviewed 14. Stentless Bioprostheses for Aortic Valve Replacement in Calcific Aortic Stenosis By Kaan Kirali		2651
Open access peer-reviewed 15. New Therapeutic Approaches to Conventional Surgery for Aortic Stenosis in High-Risk Patients By Omer Leal, Juan Bustamante, Sergio Cánovas and Ángel G. Pinto		1743
Open access peer-reviewed 16. Indications for Transcatheter Aortic Valve Implantation By Ibrahim Akin, Stephan Kische, Henrik Schneider, Tim C. Rehders, Christoph A. Nienaber and Hüseyin Ince		1563
Open access peer-reviewed 17. Aortic Valve Replacement for Calcified Aortic Valves By Kazumasa Orihashi		2712
Open access peer-reviewed 18. Congenital Aortic Stenosis in Children By Hirofumi Saiki and Hideaki Senzaki		1571

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