Open access peer-reviewed Edited Volume

Astrocyte

Physiology and Pathology

Co-editor:

A team of authors from prestigious academic schools contributed to draw up a project that would give a detailed account of astrocyte's morphology and physiology, examining thoroughly all the astrocyte's types; giving an accurate description of their morphology, location, function in the brain; and illustrating their physiology and pathology in terms of dealing with neurons through "gliotransmitters," ionic channels, and membrane receptors expression. This book gives an overview of the crucial role of astrocytes in the physiology of the CNS and in the pathogenesis of several CNS disorders suggesting that the shift from a neurocentric view to one that incorporates astrocytes in disease models for drug discovery is a critical step in renewing drug development strategies to treat neurodegenerative diseases.

Read more >Order hardcopy
IntechOpen
AstrocytePhysiology and PathologyEdited by Maria Teresa Gentile

Published: March 21st 2018

DOI: 10.5772/intechopen.69076

ISBN: 978-953-51-3886-0

Print ISBN: 978-953-51-3885-3

eBook (PDF) ISBN: 978-953-51-4077-1

Copyright year: 2018

Books open for chapter submissions

4497 Total Chapter Downloads

4 Dimensions Citations

chaptersDownloads

Open access peer-reviewed

1. Introductory Chapter: The Importance of Astrocytes in the Research of CNS Diseases

By Maria Teresa Gentile and Luca Colucci D’Amato

371

Open access peer-reviewed

2. Signaling Pathways Regulating the Pathophysiological Responses of Astrocytes: A Focus on the IKK/NF-κB System

By Michael Lattke and Thomas Wirth

332

Open access peer-reviewed

3. Evidence that Astroglia Influence Dendrite Morphogenesis and Synaptogenesis Independently in the Vertebrate Central Nervous System

By Christopher S. Wallace and Ginger S. Withers

416

Open access peer-reviewed

4. NMDA Receptors in Astroglia: Chronology, Controversies, and Contradictions from a Complex Molecule

By Pavel Montes de Oca Balderas and José Roberto González Hernández

433

Open access peer-reviewed

5. Astrocytes in Pathogenesis of ALS Disease and Potential Translation into Clinic

By Izrael Michal, Slutsky Shalom Guy, Joseph Itskovitz-Eldor and Revel Michel

523

Open access peer-reviewed

6. Astrocytes’ Role in Alzheimer’s Disease Neurodegeneration

By Ilaria Dal Prà, Ubaldo Armato and Anna Chiarini

510

Open access peer-reviewed

7. Mitochondrial Function in Alzheimer’s Disease: Focus on Astrocytes

By Riikka Lampinen, Irina Belaya, Isabella Boccuni, Tarja Malm and Katja M. Kanninen

557

Open access peer-reviewed

8. The Role of Astrocytes in Tumor Growth and Progression

By Emily Gronseth, Ling Wang, David R. Harder and Ramani Ramchandran

495

Open access peer-reviewed

9. Astrocytes in Aceruloplasminemia

By Hiroaki Miyajima

341

Open access peer-reviewed

10. Astrocyte Pathophysiology in Liver Disease

By Carlos Pérez-Monter and Aldo Torre-Delgadillo

523

Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

Order a hardcopy of the Edited Volume

Free shipping with DHL Express

Hardcover (ex. VAT)£140

Order now

Residents of European Union countries need to add a Book Value-Added Tax of 5%. Institutions and companies, registered as VAT taxable entities in their own EU member state, will not pay VAT by providing IntechOpen with their VAT registration number. This is made possible by the EU reverse charge method.

Special discount for IntechOpen contributors

All IntechOpen contributors are offered special discounts starting at 40% OFF available through your personal dashboard

Login and purchase