Open access peer-reviewed Edited Volume

Aortic Stenosis

Etiology, Pathophysiology and Treatment

Currently, aortic stenosis (AS) is the most prevalent valvular disease in developed countries. Pathological and molecular mechanisms of AS have been investigated in many aspects. And new therapeutic devices such as transcatheter aortic valve implantation have been developed as a less invasive treatment for high-risk patients. Due to advanced prevalent age of AS, further discovery and technology are required to treat elderly patients for longer life expectancy. This book is an effort to present an up-to-date account of existing knowledge, involving recent development in this field. Various opinion leaders described details of established knowledge or newly recognized advances associated with diagnosis, treatment and mechanism. Thus, this book will enable close intercommunication to another field and collaboration technology for new devices. We hope that it will be an important source, not only for clinicians, but also for general practitioners, contributing to development of better therapeutic adjuncts in the future.

Read more >Order hardcopy
Aortic StenosisEtiology, Pathophysiology and TreatmentEdited by Masanori Hirota

Published: October 10th 2011

DOI: 10.5772/801

ISBN: 978-953-307-660-7

eBook (PDF) ISBN: 978-953-51-6519-4

Copyright year: 2011

Books open for chapter submissions

40993 Total Chapter Downloads

2 Crossref Citations

2 Web of Science Citations

6 Dimensions Citations


Open access peer-reviewed

1. Aortic Stenosis - New Insights in Stenosis Progression and in Prevention

By Parolari Alessandro, Trezzi Matteo, Merati Elisa, Filippini Sara and Alamanni Francesco


Open access peer-reviewed

2. Aortic Stenosis: Geriatric Considerations

By Petar Risteski, Andreas Zierer, Nestoras Papadopoulos, Sven Martens, Anton Moritz and Mirko Doss


Open access peer-reviewed

3. Pathophysiologic Mechanisms of Age – Related Aortic Valve Calcification

By Alexandros Alexopoulos, Nikolaos Michelakakis and Helen Papadaki


Open access peer-reviewed

4. Asymptomatic Aortic Stenosis - Prognosis, Risk Stratification and Follow-Up

By Paoli Ursula and Dichtl Wolfgang


Open access peer-reviewed

5. Stress Testing in Patients with Asymptomatic Severe Aortic Stenosis

By Asim M. Rafique, Kirsten Tolstrup and Robert J. Siegel


Open access peer-reviewed

6. Analog Simulation of Aortic Stenosis

By M. Sever, S. Ribarič, F. Runovc and M. Kordaš


Open access peer-reviewed

7. Minimally Invasive Aortic Valve Surgery - New Solutions to Old Problems

By Juan Bustamante, Sergio Cánovas and Ángel L Fernández


Open access peer-reviewed

8. Technical Modifications for Patients with Aortic Stenosis and Calcified Ascending Aorta During Aortic Valve Replacement

By Masanori Hirota, Joji Hoshino, Yasuhisa Fukada, Shintaro Katahira, Taichi Kondo, Kenichi Muramatsu and Tadashi Isomura


Open access peer-reviewed

9. Transcatheter Aortic Valve Implantation: New Hope for Inoperable and High-Risk Patients

By Kentaro Hayashida and Thierry Lefèvre


Open access peer-reviewed

10. Management of Congenital Aortic Stenosis by Catheter Techniques

By Mehnaz Atiq


Open access peer-reviewed

11. Proteomics - A Powerful Tool to Deepen the Molecular Mechanisms of Aortic Stenosis Disease

By Felix Gil-Dones, Fernando de la Cuesta, Gloria Alvarez-Llamas, Luis R. Padial, Luis F. López-Almodovar, Tatiana Martín-Rojas, Fernando Vivanco and Maria G. Barderas


Open access peer-reviewed

12. The Inflammatory Infiltrate in Calcific Aortic Stenosis is Characterized by Clonal Expansions of T Cells and is Associated with Elevated Proportions of Circulating Activated and Effector Memory CD8 T Cells

By Robert Winchester and Susheel Kodali


Open access peer-reviewed

13. Natriuretic Peptides in Severe Aortic Stenosis - Role in Predicting Outcomes and Assessment for Early Aortic Valve Replacement

By Aaron Lin and Ralph Stewart


Open access peer-reviewed

14. Cellular and Neuronal Aspects in Aortic Stenosis

By J. Ker and WFP Van Heerden


Open access peer-reviewed

15. Severe Calcific Aortic Valve Stenosis and Bleeding: Heyde's Syndrome

By Giampaolo Zoffoli, Domenico Mangino, Andrea Venturini, Angiolino Asta, Alberto Terrini, Chiara Zanchettin, Francesco Battaglia and Elvio Polesel


Open access peer-reviewed

16. Hybrid Procedure in Neonatal Critical Aortic Stenosis and Borderline Left Heart: Buying Time for Left Heart Growth

By Ward Y. Vanagt, Stephen C. Brown and Marc Gewillig


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

Order a hardcopy of the Edited Volume

Free shipping with DHL Express

Hardcover (ex. VAT)£119

Order now

Residents of European Union countries need to add a Book Value-Added Tax of 5%. Institutions and companies, registered as VAT taxable entities in their own EU member state, will not pay VAT by providing IntechOpen with their VAT registration number. This is made possible by the EU reverse charge method.

Special discount for IntechOpen contributors

All IntechOpen contributors are offered special discounts starting at 40% OFF available through your personal dashboard

Login and purchase