Open access peer-reviewed Edited Volume

Antiviral Drugs

Aspects of Clinical Use and Recent Advances

Edited by Patrick Arbuthnot

University of the Witwatersrand, South Africa

The articles that appear in Antiviral Drugs - Aspects of Clinical Use and Recent Advances cover several topics that reflect the varied mechanisms of viral disease pathogenesis and treatment. Clinical management and new developments in the treatment of virus-related diseases are the two main sections of the book. The first part reviews the treatment of hepatitis C virus infection, the management of virus-related acute retinal necrosis, the use of leflunomide therapy in renal transplant patients, and mathematical modeling of HIV-1 treatment responses. Basic research topics are dealt with in the second half of the book. New developments in the treatment of the influenza virus, the use of animal models for HIV-1 drug development, the use of single chain camelid antibodies against negative strand RNA viruses, countering norovirus infection, and the use of plant extracts to treat herpes simplex virus infection are described. The content of the book is not intended to be comprehensive, but aims to provide the reader with insights into selected aspects of established and new viral therapies.

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Antiviral DrugsAspects of Clinical Use and Recent AdvancesEdited by Patrick Arbuthnot

Published: March 14th 2012

DOI: 10.5772/1061

ISBN: 978-953-51-0256-4

eBook (PDF) ISBN: 978-953-51-6885-0

Copyright year: 2012

Books open for chapter submissions

25122 Total Chapter Downloads

6 Crossref Citations

13 Web of Science Citations

14 Dimensions Citations


Open access peer-reviewed

1. Antiviral Therapy in HCV-Infected Decompensated Cirrhotics

By Fazal-I-Akbar Danish


Open access peer-reviewed

2. Virus Diagnostics and Antiviral Therapy in Acute Retinal Necrosis (ARN)

By Peter Rautenberg, Jost Hillenkamp, Livia Grančičova, Bernhard Nölle, Johann Roider and Helmut Fickenscher


Open access peer-reviewed

3. Leflunomide an Immunosuppressive Drug for Antiviral Purpose in Treatment for BK Virus-Associated Nephropathy After Kidney Transplantation

By Christophe Bazin


Open access peer-reviewed

4. Modeling Virologic Response in HIV-1 Infected Patients to Assess Medication Adherence

By Yangxin Huang


Open access peer-reviewed

5. Use of Animal Models for Anti-HIV Drug Development

By Zandrea Ambrose


Open access peer-reviewed

6. Discovery of Novel Antiviral Agents Directed Against the Influenza A Virus Nucleoprotein

By Yoko Aida, Yutaka Sasaki and Kyoji Hagiwara


Open access peer-reviewed

7. Targeting Norovirus: Strategies for the Discovery of New Antiviral Drugs

By Joana Rocha-Pereira and Maria São José Nascimento


Open access peer-reviewed

8. Single Domain Camelid Antibodies that Neutralize Negative Strand Viruses

By Francisco Miguel Lopez Cardoso, Lorena Itatí Ibañez, Bert Schepens and Xavier Saelens


Open access peer-reviewed

9. Treatment of Herpes Simplex Virus with Lignin-Carbohydrate Complex Tablet, an Alternative Therapeutic Formula

By Blanca Silvia González López, Masaji Yamamoto and Hiroshi Sakagami


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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