Open access peer-reviewed Edited volume

Alzheimer's Disease

The 21st Century Challenge

Co-editor:

Alzheimer's disease was discovered over 100 years ago and still belongs to incurable neurological diseases; its pharmacotherapy is considered to be ineffective. This book presents contemporary views on the genetic, biochemical, and immunological determinants of this disease. This book also concerns the issue of Alzheimer's disease prevention through lifestyle and physical activity. Moreover, it describes the therapies used in Alzheimer's disease to slow the progression of the disease and delay its onset. Subsequently, the authors discuss experimental and clinical trials used now and in the near future. We hope that this book will help the readers to understand the complex mechanism leading to the development of Alzheimer's disease and indicate effective ways to prevent this disorder.

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Alzheimer's DiseaseThe 21st Century ChallengeEdited by Jolanta Dorszewska

Published: July 18th 2018

DOI: 10.5772/intechopen.71628

ISBN: 978-1-78923-463-3

Print ISBN: 978-1-78923-462-6

Copyright year: 2018

Books open for chapter submissions

431 Total Chapter Downloads

chaptersDownloads

Open access peer-reviewed

1. Amyloid Beta Hypothesis: Attention to β- and γ-Secretase Modulators

By Jan Korabecny, Katarina Spilovska, Ondrej Soukup, Rafael Dolezal and Kamil Kuca

49

Open access peer-reviewed

2. Alzheimer’s Disease: Beyond the Neuron

By Aradhana Verma and Matthew Zabel

78

Open access peer-reviewed

3. Defining Microglial Phenotypes in Alzheimer’s Disease

By Douglas Walker and Lih-Fen Lue

45

Open access peer-reviewed

4. Mitochondrial Link Between Metabolic Syndrome and Pre-Alzheimer’s Disease

By Nattayaporn Apaijai, Wasana Pratchayasakul, Nipon Chattipakorn and Siriporn C. Chattipakorn

51

Open access peer-reviewed

5. Lithium and Alzheimer’s Disease: Experimental, Epidemiological, and Clinical Findings

By Janusz K. Rybakowski

54

Open access peer-reviewed

6. Mild Cognitive Impairment

By Marina Janelidze and Nazibrola Botchorishvili

46

Open access peer-reviewed

7. Challenges in Dementia Studies

By Kevin T. Ong

54

Open access peer-reviewed

8. Passive Immunotherapy in Alzheimer’s Disease

By Philip J. Dolan and Wagner Zago

54

Edited volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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