Open access peer-reviewed Edited Volume

Advances in the Molecular Understanding of Colorectal Cancer

Edited by Eva Segelov

Monash University

An understanding of the molecular pathogenesis of colorectal cancer by researchers and clinicians is essential to facilitate progress in improving patient outcomes in this common cancer that still carries a poor prognosis if not identified early. This book covers the major areas of importance in the field, incorporating new knowledge that has arisen due to the advancement of molecular techniques and the ability to correlate molecular changes with clinical behaviour of tumours. Each chapter is a summary written by experts, concisely summarising current data as well as highlighting potential areas for advancement. Appreciating the differences between tumours on a molecular level is the key to developing and delivering precision medicine, and nowhere is this more critically required than in the field of colorectal cancer.

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IntechOpen
Advances in the Molecular Understanding of Colorectal CancerEdited by Eva Segelov

Published: February 6th 2019

DOI: 10.5772/intechopen.77960

ISBN: 978-1-78985-060-4

Print ISBN: 978-1-78985-059-8

Copyright year: 2019

Books open for chapter submissions

1844 Total Chapter Downloads

chaptersDownloads

Open access peer-reviewed

1. Advances in Molecular Subclassification of Colorectal Cancer

By Avani Athauda and Ian Chau

208

Open access peer-reviewed

2. Experimental Results Help Shape the Development of Personalized Medicine in Colorectal Cancer

By Rania B. Georges, Hassan Adwan and Martin R. Berger

147

Open access peer-reviewed

3. BRAF Mutation and Its Importance in Colorectal Cancer

By Lee-Jen Luu and Timothy J. Price

378

Open access peer-reviewed

4. Current Utility and Future Applications of ctDNA in Colorectal Cancer

By Daphne Day, Sophia Frentzas, Cameron A. Naidu, Eva Segelov and Maja Green

329

Open access peer-reviewed

5. Epigenetic Biomarkers and Their Therapeutic Applications in Colorectal Cancer

By Antja-Voy Hartley, Matthew Martin and Tao Lu

264

Open access peer-reviewed

6. Predictive Biomarkers for Monoclonal Antibody Therapies Targeting EGFR (Cetuximab, Panitumumab) in the Treatment of Metastatic Colorectal Cancer

By Anuratha Sakthianandeswaren, Polly Sabljak, Meg J. Elliott, Michelle Palmieri and Oliver M. Sieber

293

Open access peer-reviewed

7. Finding Needles in Haystacks: The Use of Quantitative Proteomics for the Early Detection of Colorectal Cancer

By Tiffany Gould, Muhammad Fairuz B. Jamaluddin, Joel Petit, Simon J. King, Brett Nixon, Rodney Scott, Peter Pockney and Matthew D. Dun

225

Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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