Open access peer-reviewed Edited Volume

Acute Leukemias

Edited by Pier Paolo Piccaluga

University of Bologna

Written by expert research teams, this book describes different aspects of both acute myeloid and acute lymphocytic leukemia, specifically their pathobiology, classification/diagnosis, and treatment. Chapters highlight current research as well as the gold standards for diagnosis and treatment of these diseases, examining recent advances in personalized approaches to acute leukemia.

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Acute LeukemiasEdited by Pier Paolo Piccaluga

Published: March 24th 2021

DOI: 10.5772/intechopen.87292

ISBN: 978-1-83881-169-3

Print ISBN: 978-1-83881-168-6

eBook (PDF) ISBN: 978-1-83881-173-0

Copyright year: 2021

Books open for chapter submissions

2476 Total Chapter Downloads


Open access peer-reviewed

1. Introductory Chapter: A Brief History of Acute Leukemias Treatment

By Pier Paolo Piccaluga


Open access peer-reviewed

2. Juvenile Myelomonocytic Leukemia (JMML): A Mimicker of KMT2A-Rearranged Acute Myeloid Leukemia (AML)

By Ashraf Abdullah Saad


Open access peer-reviewed

3. Reactive Oxygen Species and Metabolic Re-Wiring in Acute Leukemias

By Andrew J. Robinson, Richard L. Darley and Alex Tonks


Open access peer-reviewed

4. The Key Role of the Phosphatase PP2A in the Development of Acute Myeloid Leukemia

By Javier Marco, Irene Peris, Carmen Vicente and Elena Arriazu


Open access peer-reviewed

5. Melanin, from an Evolutionary Remnant to the Myeloid Lineage Cell’s Main Energy Source. The Unsuspected Intrinsic Property of Melanin to Dissociate the Molecule from Water. Possible Implications in the Context of Acute Leukemias

By Arturo Solís Herrera, Ruth I. Solís Arias and Luis F. Torres Solís


Open access peer-reviewed

6. Self-Renewal Pathways in Acute Myeloid Leukemia Stem Cells

By Jonason Yang, Nunki Hassan, Sheng Xiang Franklin Chen, Jayvee Datuin and Jenny Y. Wang


Open access peer-reviewed

7. MicroRNAs and Their Role in Acute Lymphoblastic Leukemia

By Edgardo Becerra Becerra and Guadalupe García-Alcocer


Open access peer-reviewed

8. Acute Lymphoblastic Leukemia in Adolescents and Young Adults

By Martha Alvarado-Ibarra, José Antonio De la Peña Celaya, Luara Luz Arana-Luna, Eleazar Hernández-Ruiz, José Luis Alvarez Vera, María Eugenia Espitia Ríos and Juan Manuel Pérez Zúñiga


Open access peer-reviewed

9. What Is the Best Choice and Dose of Anthracycline for Induction Chemotherapy in Acute Myeloid Leukemia?

By Sravanti Rangaraju and Omer Jamy


Open access peer-reviewed

10. Treatment of AML in Older Patients

By Jacobien Hilberink and Gerwin Huls


Open access peer-reviewed

11. Stem Cell Transplantation in Acute Myeloid Laeukemia

By Salvatore Leotta, Annalisa Condorelli, Giovanni Schininà, Roberta Sciortino, Alessandra Cupri and Giuseppe Milone


Open access peer-reviewed

12. Consolidation: Autologous Stem Cell Transplantation in Acute Leukemia

By Fatma Keklik Karadağ, Fahri Şahin and Güray Saydam


Open access peer-reviewed

13. Molecular Monitoring in Acute Myeloid Leukemia Patients Undergoing Matched Unrelated Donor: Hematopoietic Stem Cell Transplantation

By Irina Panovska-Stavridis


Open access peer-reviewed

14. Target Therapy in Acute Myeloid Leukemia

By Vasko Graklanov


Open access peer-reviewed

15. Targeting of Post-Transcriptional Regulation as Treatment Strategy in Acute Leukemia

By Paulina Podszywalow-Bartnicka, Magdalena Wolczyk and Katarzyna Piwocka


Open access peer-reviewed

16. Mechanisms of Resistence of New Target Drugs in Acute Myeloid Leukemia

By Debora Capelli, Francesco Saraceni, Diego Menotti, Alessandro Fiorentini and Attilio Olivieri


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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