Open access peer-reviewed Edited Volume

Vasculogenesis and Angiogenesis

from Embryonic Development to Regenerative Medicine

Edited by Dan Simionescu

Clemson University


Vasculogenesis is the process of new blood vessel formation during embryonic development of the cardiovascular system. This is followed by formation of a vascular tree and finally the cardiovascular system with the myriad of blood vessels that nourish all tissues and organs. Angiogenesis, on the other hand is the process by which new blood vessels take shape from existing blood vessels by "sprouting" of endothelial cells thus expanding the vascular tree. Both scenarios are based on activation, migration, proliferation and maturation of unique precursor cells. The study of blood vessel formation is an essential component of embryonic development, congenital malformations, degenerative diseases, inflammation and cancer and thus has widespread appeal to the biomedical field. Moreover, scientists are now harnessing this information for the purpose of building living blood vessel substitutes for replacement of diseased arteries and veins. This book highlights novel advances in the field of vasculogenesis and angiogenesis, including embryogenesis and development, regulation of progenitor cells, cancer and blood vessel regeneration. We consider this book a good initial source of information for graduate students, medical students and scientists interested in the intricacies of blood vessel formation, maturation, disease and replacement.

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Vasculogenesis and Angiogenesisfrom Embryonic Development to Regenerative MedicineEdited by Dan Simionescu

Published: November 7th 2011

DOI: 10.5772/1341

ISBN: 978-953-307-882-3

eBook (PDF) ISBN: 978-953-51-6747-1

Copyright year: 2011

Books open for chapter submissions

19256 Total Chapter Downloads

5 Crossref Citations

13 Web of Science Citations

7 Dimensions Citations


Open access peer-reviewed

1. Human Embryonic Blood Vessels: What Do They Tell Us About Vasculogenesis and Angiogenesis?

By Simona Sârb, Marius Raica and Anca Maria Cîmpean


Open access peer-reviewed

2. Cardiac Vasculature: Development and Pathology

By Michiko Watanabe, Jamie Wikenheiser, Diana Ramirez-Bergeron, Saul Flores, Amir Dangol, Ganga Karunamuni, Akshay Thomas, Monica Montano and Ravi Ashwath


Open access peer-reviewed

3. Vascular Growth in the Fetal Lung

By Stephen C. Land


Open access peer-reviewed

4. Apelin Signalling: Lineage Marker and Functional Actor of Blood Vessel Formation

By Yves Audigier


Open access peer-reviewed

5. Regulation of Endothelial Progenitor Cell Function by Plasma Kallikrein-Kinin System

By Yi Wu and Jihong Dai


Open access peer-reviewed

6. Vasculogenesis in Diabetes-Associated Diseases: Unraveling the Diabetic Paradox

By Carla Costa


Open access peer-reviewed

7. Modeling Tumor Angiogenesis with Zebrafish

By Alvin C.H. Ma, Yuhan Guo, Alex B.L. He and Anskar Y.H. Leung


Open access peer-reviewed

8. Therapeutic and Toxicological Inhibition of Vasculogenesis and Angiogenesis Mediated by Artesunate, a Compound with Both Antimalarial and Anticancer Efficacy

By Qigui Li, Mark Hickman and Peter Weina


Open access peer-reviewed

9. The Mechanics of Blood Vessel Growth

By Rui D. M. Travasso


Open access peer-reviewed

10. A Novel Adult Marrow Stromal Stem Cell Based 3-D Postnatal De Novo Vasculogenesis for Vascular Tissue Engineering

By Mani T. Valarmathi and John W. Fuseler


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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