Open access peer-reviewed Edited Volume


New Approaches and Prospects

Edited by Matilde Otero-Losada

University of Buenos Aires


Francisco Capani

University of Buenos Aires

Santiago Perez Lloret

University of Buenos Aires

Neurological disease affects nearly 25%–30% of the world’s population, exerting enormous financial strain on the healthcare system. Estimated current costs are around $800 annual billion, and this number is expected to increase exponentially as the global population ages. As such, new and alternative neuroprotective strategies are urgently needed. This book examines some of the most promising approaches in neuroprotection as well as discusses current goals and prospects. Organized into three sections, chapters cover such topics as the use of cannabinoids, medicinal plants, and essential oils in Alzheimer’s and Parkinson’s; protein misfolding and the neuroprotective potential of vitamin E in cerebral ischemia; and potential new neurological treatments and their mechanisms of action.

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NeuroprotectionNew Approaches and ProspectsEdited by Matilde Otero-Losada

Published: November 26th 2020

DOI: 10.5772/intechopen.77918

ISBN: 978-1-83880-440-4

Print ISBN: 978-1-83880-439-8

eBook (PDF) ISBN: 978-1-83969-261-1

Copyright year: 2020

Books open for chapter submissions

5510 Total Chapter Downloads

3 Crossref Citations

1 Web of Science Citations

6 Dimensions Citations


Open access peer-reviewed

1. Neuroprotective Properties of Cannabinoids in Cellular and Animal Models: Hypotheses and Facts

By Lucas D. Udovin, Andrea Aguilar, Tamara Kobiec, María I. Herrera, Santiago Perez Lloret, Nicolás Toro Urrego and Rodolfo A. Kölliker Frers


Open access peer-reviewed

2. An Alternate View of Neuroprotection with Peptides in Alzheimer’s Disease

By Samuel King and Cenk Suphioglu


Open access peer-reviewed

3. Polyphenols as Potential Therapeutic Drugs in Neurodegeneration

By Patrizia Polverino de Laureto, Luana Palazzi and Laura Acquasaliente


Open access peer-reviewed

4. Extracts and Essential Oils from Medicinal Plants and Their Neuroprotective Effect

By Ianara Mendonça da Costa, Elaine Cristina Gurgel Andrade Pedrosa, Ana Paula de Carvalho Bezerra, Luciana Cristina Borges Fernandes, José Rodolfo Lopes de Paiva Cavalcanti, Marco Aurélio Moura Freire, Dayane Pessoa de Araújo, Amália Cinthia Meneses do Rego, Irami Araujo Filho, Francisco Irochima Pinheiro and Fausto Pierdoná Guzen


Open access peer-reviewed

5. Glycodendrimers as Potential Multitalented Therapeutics in Alzheimer’s Disease

By Oxana Klementieva


Open access peer-reviewed

6. Alzheimer’s Disease Neuroprotection: Associated Receptors

By Alice Barros Câmara


Open access peer-reviewed

7. In Vivo Studies of Protein Misfolding and Neurodegeneration Induced by Metabolic Syndrome Relative to Chronic Cerebral Hypoperfusion: A Critical Review

By María I. Herrera, Juan P. Luaces, Lucas D. Udovin, Nicolás Toro-Urrego, Matilde Otero-Losada and Francisco Capani


Open access peer-reviewed

8. Neuroprotective and Neurorestorative Properties of Copolymer-1: Its Immunomodulating Effects on Ischemic Stroke

By María Yolanda Cruz Martínez, Melanie Tessa Saavedra Navarrete and José Juan Antonio Ibarra Arias


Open access peer-reviewed

9. Trends in Neuroprotective Strategies after Spinal Cord Injury: State of the Art

By Roxana Rodríguez-Barrera, Marcela Garibay-López and Antonio Ibarra


Open access peer-reviewed

10. Neuroprotective Potentials of Natural Vitamin E for Cerebral Small Vessel Disease

By Muzaimi Mustapha, Che Mohd Nasril Che Mohd Nassir, Yuen Kah Hay, Fung Wai Yee and Hafizah Abdul Hamid


Open access peer-reviewed

11. Neuroactive Steroids in Hypoxic–Ischemic Brain Injury: Overview and Future Directions

By Nicolas Toro-Urrego, Marco Avila-Rodriguez, María Inés Herrera, Andrea Aguilar, Lucas Udovin and Juan P. Luaces


Open access peer-reviewed

12. Glyproline Pro-Ampakine with Neuroprotective Activity

By Ksenia N. Koliasnikova, Polina Yu. Povarnina, Anna V. Tallerova, Yulia N. Firsova, Sergei V. Nikolaev, Tatiana A. Antipova, Anna V. Nadorova, Larisa G. Kolik, Tatiana A. Gudasheva and Sergei B. Seredenin


Open access peer-reviewed

13. Aptamers and Possible Effects on Neurodegeneration

By Fatma Söylemez and Çağatay Han Türkseven


Open access peer-reviewed

14. Lifestyle Factors, Mitochondrial Dynamics, and Neuroprotection

By Katheryn Broman, Abigail U. Davis, Jordan May and Han-A Park


Open access peer-reviewed

15. Hydrogen Sulfide as a Factor of Neuroprotection during the Constitutive and Reparative Neurogenesis in Fish Brain

By Evgeniya V. Pushchina, Anatoly A. Varaksin and Dmitry K. Obukhov


Open access peer-reviewed

16. Neuroprotection: The Way of Anti-Inflammatory Agents

By Patrice Mendel Nzogang and Martial Boris Donkeng


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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