Open access peer-reviewed Edited Volume

Cartilage Tissue Engineering and Regeneration Techniques

Edited by Dimitrios D. Nikolopoulos

Central Clinic of Athens


George K. Safos

Central Clinic of Athens

Kalpaxis Dimitrios

Orthopaedic Research Institute for Education and Training

Osteochondral defects can be challenging to treat, first, because the damaged articular cartilage has a poor intrinsic reparative capability, and second, because these defects cause chronic pain and serious disability. That is why cartilage repair remains one of the most challenging issues of musculoskeletal medicine. Arthroscopic and open techniques that have been developed over the last two decades intend to promote the success of complete repair of the articular cartilage defects; nevertheless, these therapies cannot always offer 100% success. Nowadays, cartilage tissue engineering is an emerging technique for the regeneration of cartilage tissue. Taking into consideration these perspectives, this book aims to present a summary of cartilage tissue engineering, including development, recent progress, and major steps taken toward the regeneration of functional cartilage tissue. Special emphasis is placed on the role of stimulating factors, including growth factors, gene therapies, as well as scaffolds, including natural, synthetic, and nanostructured.

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Cartilage Tissue Engineering and Regeneration TechniquesEdited by Dimitrios D. Nikolopoulos

Published: June 5th 2019

DOI: 10.5772/intechopen.77717

ISBN: 978-1-78923-850-1

Print ISBN: 978-1-78923-849-5

eBook (PDF) ISBN: 978-1-83880-781-8

Copyright year: 2019

Books open for chapter submissions

7368 Total Chapter Downloads

11 Crossref Citations

1 Web of Science Citations

21 Dimensions Citations


Open access peer-reviewed

1. Cartilage Tissue Engineering and Regeneration

By Francisco Sousa Segundo, Marcelo Jorge Cavalcanti de Sá and Roberto Lopes de Souza


Open access peer-reviewed

2. Epigenetics and Cartilage Regeneration

By Samina Hyder Haq, Iqraa Haq, Atheer Ali Alsayah, Abir Alamro and Amani AlGhamedi


Open access peer-reviewed

3. Nonsurgical Strategies for the Treatment of Temporomandibular Joint Disorders

By Juan L. Cobo, Manuela Cabrera-Freitag, Teresa Cobo, Juan D. Muriel, Luis M. Junquera, Juan Cobo and José A. Vega


Open access peer-reviewed

4. The Potential Effect of Medicinal Plants for Cartilage Regeneration

By Franca Nneka Alaribe, Mapula Razwinani, Makwese Maepa and Keolebogile Shirley Caroline Motaung


Open access peer-reviewed

5. Reconstruction with Joint Preservation

By Lourenço Galizia Heitzmann


Open access peer-reviewed

6. Current Tissue Engineering Approaches for Cartilage Regeneration

By He Huang, Hongyao Xu and Jianying Zhang


Open access peer-reviewed

7. Cartilage Tissue Engineering Using Self-Assembling Peptides Composite Scaffolds

By Nausika Betriu and Carlos E. Semino


Open access peer-reviewed

8. Therapeutic Potential of Articular Cartilage Regeneration using Tissue Engineering Based on Multiphase Designs

By Lizeth Fuentes-Mera, Alberto Camacho, Elisabeth Engel, Vanessa Pérez-Silos, Jorge Lara-Arias, Iván Marino-Martínez and Víctor Peña-Martínez


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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