Open access peer-reviewed Edited Volume

Ovarian Cancer

Basic Science Perspective

Worldwide, Ovarian carcinoma continues to be responsible for more deaths than all other gynecologic malignancies combined. International leaders in the field address the critical biologic and basic science issues relevant to the disease. The book details the molecular biological aspects of ovarian cancer. It provides molecular biology techniques of understanding this cancer. The techniques are designed to determine tumor genetics, expression, and protein function, and to elucidate the genetic mechanisms by which gene and immunotherapies may be perfected. It provides an analysis of current research into aspects of malignant transformation, growth control, and metastasis. A comprehensive spectrum of topics is covered providing up to date information on scientific discoveries and management considerations.

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Ovarian CancerBasic Science PerspectiveEdited by Samir Farghaly

Published: February 17th 2012

DOI: 10.5772/1268

ISBN: 978-953-307-812-0

eBook (PDF) ISBN: 978-953-51-6640-5

Copyright year: 2012

Books open for chapter submissions

41635 Total Chapter Downloads

13 Crossref Citations

26 Web of Science Citations

30 Dimensions Citations


Open access peer-reviewed

1. Epidemiology and Etiology of Ovarian Cancer

By Ana Fernández Montes, Jesús García Gómez, Miguel Nuñez Viejo, Miguel Alonso Bermejo, Susana Alonso Urrutia and Jesús García Mata


Open access peer-reviewed

2. Inflammation and Ovarian Cancer

By Antonio Macciò and Clelia Madeddu


Open access peer-reviewed

3. Photonic Sensor System for Screening Serum Biomarker Proteins in Ovarian Cancer

By Debra Wawro, Shelby Zimmerman, Robert Magnusson and Peter Koulen


Open access peer-reviewed

4. The Role of MUC16 Mucin (CA125) in the Pathogenesis of Ovarian Cancer

By Claudine Rancourt, Isabelle Matte, Denis Lane and Alain Piché


Open access peer-reviewed

5. Apoptosis Pathways in Ovarian Cancer

By Christine Sers, Reinhold Schafer and Irina Nazarenko


Open access peer-reviewed

6. Oncogenic Pathway Signatures and Survival Outcome

By Xuan Bich Trinh, Peter A. Van Dam, Luc Y. Dirix, Steven J. van Laere and Wiebren A. A. Tjalma


Open access peer-reviewed

7. Dysregulated TGFB Signaling in Ovarian Cancer

By Kyle Bauckman, Christie Campla and Meera Nanjundan


Open access peer-reviewed

8. New Tumor Biomarkers in Ovarian Cancer and Its Prognostic and Clinical Relevance

By Malgorzata Banys, Natalia Krawczyk and Tanja Fehm


Open access peer-reviewed

9. Sensitive Detection of Epithelial Ovarian Cancer Biomarkers Using Tag-Laser Induced Breakdown Spectroscopy

By Yuri Markushin and Noureddine Melikechi


Open access peer-reviewed

10. Homeobox Genes and Their Functional Significance in Ovarian Tumorigenesis

By Bon Quy Trinh and Honami Naora


Open access peer-reviewed

11. Transcriptomic Analysis of Human Ovarian Cancer Cells: Changes Mediated by Luteinizing Hormone Receptor Activation

By Juan Cui, Ying Xu and David Puett


Open access peer-reviewed

12. Potential Tumor Biomarkers for Ovarian Cancer

By Ryan Serio and Blase Billack


Open access peer-reviewed

13. Ectoenzymes in Epithelial Ovarian Carcinoma: Potential Diagnostic Markers and Therapeutic Targets

By Nicola Lo Buono, Simona Morone, Rossella Parrotta, Alice Giacomino, Erika Ortolan and Ada Funaro


Open access peer-reviewed

14. P53 Network in Ovarian Cancer

By Fabiola Moretti and Francesca Mancini


Open access peer-reviewed

15. Gene Amplification in Ovarian Carcinomas: Lessons from Selected Amplified Gene Families

By Stéphanie Gaillard


Open access peer-reviewed

16. Nitric Oxide/Protein Kinase G-Iα Promotes c-Src Activation, Proliferation and Chemoresistance in Ovarian Cancer

By Ronald R. Fiscus, Elaine L. Leung, Janica C. Wong and Mary G. Johlfs


Open access peer-reviewed

17. VEGF Targeting Agents in Ovarian Cancer

By Seiji Mabuchi, Atsuko Wakabayashi and Tadashi Kimura


Open access peer-reviewed

18. Autotaxin – A Target for the Treatment of Drug-Resistant Ovarian Cancer?

By John King-Underwood, Steven M. Allin, Charles W. Redman and Alan Richardson


Open access peer-reviewed

19. Potential Monoclonal Antibody Therapy for the Treatment of Ovarian Cancer

By Gregory Lee, Mingang Zhu and Bixia Ge


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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