Open access peer-reviewed Edited Volume

Sarcoidosis and Granulomatosis

Diagnosis and Management

Sarcoidosis is a multi-organ, granulomatous disease the etiology of which remains unknown. It is characterized by T-cell dysfunction and B-cell hyperactivity with increased local immune activity and inflammation that leads to the formation of noncaseating granulomas in the organs involved. The lung and lymphatic system are the most commonly affected organs, however virtually any organ may be affected. Other common sites of involvement include the skin, eye, central nervous system, and the heart. Patients may present different symptoms related to the disease stage and the specific organ involved. Sarcoidosis is a global disease, and its prevalence has increased twofold over the past years. Due to the clinical heterogeneity and variable diagnostic criteria in different countries, it is difficult to calculate the exact prevalence and incidence of sarcoidosis. Age, sex, race, and geographic origin significantly influence the incidence of sarcoidosis. The book at hand seeks to assess the current diagnostic techniques, imaging techniques, differential diagnosis of this disease, as well as other granulomatous diseases mimicking sarcoidosis.

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Sarcoidosis and GranulomatosisDiagnosis and ManagementEdited by Mohammad Hosein Motamedi

Published: July 29th 2020

DOI: 10.5772/intechopen.73968

ISBN: 978-1-83962-833-7

Print ISBN: 978-1-83881-035-1

eBook (PDF) ISBN: 978-1-83962-834-4

Copyright year: 2020

Books open for chapter submissions

3442 Total Chapter Downloads


Open access peer-reviewed

1. Introductory Chapter: Orofacial Sarcoidosis and Noncaseating Granulomatosis

By Sharareh Kamfar, Taghi Azizi and Mohammad Hosein Kalantar Motamedi


Open access peer-reviewed

2. Current Diagnostic Techniques in Sarcoidosis

By Rajarajan Anandavelu and Ahmed Fahim


Open access peer-reviewed

3. Early Diagnosis of Sarcoidosis

By Marica Tina Maccarone


Open access peer-reviewed

4. Pathology of Sarcoidosis and Differential Diagnostics of other Granulomatous Diseases

By Maria V. Samsonova and Andrey L. Chernyaev


Open access peer-reviewed

5. Clinical Manifestations of Sarcoidosis and Granulomatous Disorders

By Suchibrata Das


Open access peer-reviewed

6. Granulomatous Interstitial Nephritis in Children Resulting from Wegener’s Granulomatosis, Crohn’s Disease, or Sarcoidosis

By Galina Makovetskaya, Lilia Mazur and Elena Balashova


Open access peer-reviewed

7. Cardiac Sarcoidosis

By Jhan Carlos Altamar Castillo and Miguel Jose Tejeda Camargo


Open access peer-reviewed

8. Particularities of Hepatic Sarcoidosis

By Laura Iliescu and Letitia Toma


Open access peer-reviewed

9. Sarcoid Granulomas in Malignancy

By Komal Arora, Neeraj Kaur and Jae Y. Ro


Open access peer-reviewed

10. Sarcoid Involvement of the Mammary Gland

By Patricia López Arribas, Elena Martínez Gómez and Álvaro Zapico Goñi


Open access peer-reviewed

11. Granulomatous Diseases Mimicking Sarcoidosis

By Angel Robles-Marhuenda


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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