Open access peer-reviewed Edited Volume

Osteogenesis and Bone Regeneration

Edited by Haisheng Yang

Beijing University of Technology

Osteogenesis is a core component of the skeletal system and depends on the well-coordinated proliferation and differentiation of osteogenic cells. Multiple signaling pathways and transcriptional factors tightly regulate the process of osteogenesis. Any abnormities in bone formation could cause severe disorders such as osteogenesis imperfecta and osteoporosis. Bone regeneration, a complex and well-orchestrated physiological process of osteogenesis, remains a medical challenge in the field of orthopedics and maxillofacial surgery. This book provides an overview of the current developments in osteogenesis and bone regeneration, including molecular and cellular mechanisms, physical therapies (low-level laser, distraction osteogenesis), biological therapies (mesenchymal stem cells, stem cell derived exosomes, inflammatory factor, Chinese medicine), as well as tissue engineering approaches promoting bone regeneration by targeting osteogenesis.

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Osteogenesis and Bone RegenerationEdited by Haisheng Yang

Published: April 24th 2019

DOI: 10.5772/intechopen.73955

ISBN: 978-1-78985-768-9

Print ISBN: 978-1-78985-767-2

eBook (PDF) ISBN: 978-1-83962-146-8

Copyright year: 2019

Books open for chapter submissions

9148 Total Chapter Downloads

9 Crossref Citations

1 Web of Science Citations

21 Dimensions Citations


Open access peer-reviewed

1. Bone Development and Growth

By Rosy Setiawati and Paulus Rahardjo


Open access peer-reviewed

2. Wnt Signaling and Genetic Bone Diseases

By Yanqin Lu and Jinxiang Han


Open access peer-reviewed

3. Potential Therapeutic Applications of Exosomes in Bone Regenerative Medicine

By Jiazhao Yang, Wanbo Zhu, Jinsen Lu, Kai Xie, Shiyuan Fang and Lixin Kan


Open access peer-reviewed

4. Role of Inflammatory Factors in Regulation of Osteogenesis in Tissue-Engineered Bone

By Yandong Mu, Lu Yang, Chenglong Li and Wei Qing


Open access peer-reviewed

5. Traditional Chinese Medicine Therapy for Targeting Osteoblastogenesis

By Yanqiu Liu


Open access peer-reviewed

6. Alternative Strategies for Stem Cell Osteogenic Differentiation

By Carla Cristina Gomes Pinheiro and Daniela Franco Bueno


Open access peer-reviewed

7. Distraction Osteogenesis in Oral and Craniomaxillofacial Reconstructive Surgery

By Firdaus Hariri, Siok Yoong Chin, Jonathan Rengarajoo, Qi Chao Foo, Siti Nur Nabihah Zainul Abidin and Ahmad Fadhli Ahmad Badruddin


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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