Open access peer-reviewed Edited Volume

Calibration and Validation of Analytical Methods

A Sampling of Current Approaches

Edited by Mark Stauffer

University of Pittsburgh at Greensburg, United States of America

This book seeks to introduce the reader to current methodologies in analytical calibration and validation. This collection of contributed research articles and reviews addresses current developments in the calibration of analytical methods and techniques and their subsequent validation. Section 1, "Introduction," contains the Introductory Chapter, a broad overview of analytical calibration and validation, and a brief synopsis of the following chapters. Section 2 "Calibration Approaches" presents five chapters covering calibration schemes for some modern analytical methods and techniques. The last chapter in this section provides a segue into Section 3, "Validation Approaches," which contains two chapters on validation procedures and parameters. This book is a valuable source of scientific information for anyone interested in analytical calibration and validation.

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Calibration and Validation of Analytical MethodsA Sampling of Current ApproachesEdited by Mark Stauffer

Published: April 25th 2018

DOI: 10.5772/intechopen.69918

ISBN: 978-1-78923-085-7

Print ISBN: 978-1-78923-084-0

eBook (PDF) ISBN: 978-1-83881-442-7

Copyright year: 2018

Books open for chapter submissions

18109 Total Chapter Downloads

18 Crossref Citations

18 Web of Science Citations

39 Dimensions Citations


Open access peer-reviewed

1. Introductory Chapter: The Many Faces of Calibration and Validation in Analytical Methodology in the Present Day

By Mark T. Stauffer


Open access peer-reviewed

2. Analytical Calibrations: Schemes, Manuals, and Metrological Deliberations

By Marwa S. El-Azazy


Open access peer-reviewed

3. Multivariate Calibration for the Development of Vibrational Spectroscopic Methods

By Ioan Tomuta, Alina Porfire, Tibor Casian and Alexandru Gavan


Open access peer-reviewed

4. Internal Standards for Absolute Quantification of Large Molecules (Proteins) from Biological Matrices by LC-MS/MS

By Morse Faria and Matthew S. Halquist


Open access peer-reviewed

5. Calibration Methods of Laser-Induced Breakdown Spectroscopy

By Hongbo Fu, Junwei Jia, Huadong Wang, Zhibo Ni and Fengzhong Dong


Open access peer-reviewed

6. Linearity of Calibration Curves for Analytical Methods: A Review of Criteria for Assessment of Method Reliability

By Seyed Mojtaba Moosavi and Sussan Ghassabian


Open access peer-reviewed

7. Validation of Analytical Methods

By Tentu Nageswara Rao


Open access peer-reviewed

8. Method Validation Approaches for Pharmaceutical Assessments – Highlights with High Performance Thin Layer Chromatographic (HPTLC) Techniques

By David Jenkins, Cherif Diallo, Ed Bethea, Eliangiringa Kaale and Thomas Layloff


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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