Open access peer-reviewed Edited Volume

Pharmacokinetics and Adverse Effects of Drugs

Mechanisms and Risks Factors

Edited by Ntambwe Malangu

Sefako Makgatho Health Sciences University

This book is a fruit of a collaborative work from several international scientists. It will be a useful resource for researchers, students, and clinicians. Each individual chapter could serve as a prescribed reading for postgraduate students and clinicians specializing in and practicing clinical pharmacology and toxicology, pharmacotherapy and pharmacotherapeutics, pharmacovigilance, and toxicovigilance, as well as those involved in clinical research, drug discovery, and development. Every chapter in this book discusses and provides illustrations on the theme discussed based on authors' understanding and experience while summarizing existing knowledge. In doing so, each chapter provides a new insight that would benefit a novice as well as a seasoned reader in understanding the pharmacokinetic mechanisms and risk factors involved in the occurrence of adverse effects of drugs.

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Pharmacokinetics and Adverse Effects of DrugsMechanisms and Risks FactorsEdited by Ntambwe Malangu

Published: May 23rd 2018

DOI: 10.5772/intechopen.68518

ISBN: 978-1-78923-139-7

Print ISBN: 978-1-78923-138-0

eBook (PDF) ISBN: 978-1-83881-326-0

Copyright year: 2018

Books open for chapter submissions

9477 Total Chapter Downloads

15 Crossref Citations

4 Web of Science Citations

28 Dimensions Citations


Open access peer-reviewed

1. Introductory Chapter: Linkages between Pharmacokinetics and Adverse Effects of Drugs

By Ntambwe Malangu


Open access peer-reviewed

2. Pharmacokinetics and Disposition of Green Tea Catechins

By Kai On Chu and Calvin C.P. Pang


Open access peer-reviewed

3. A Critical Risk Factor for a Major Side Effect of Interferon-Alpha Therapy: Activated Indoleamine 2,3-Dioxygenase 1 is Related to Depressive Symptoms

By Yuki Murakami and Yukio Imamura


Open access peer-reviewed

4. Application of Pharmacokinetics in Early Drug Development

By Katherine Dunnington, Natacha Benrimoh, Christine Brandquist, Nadia Cardillo-Marricco, Mike Di Spirito and Julie Grenier


Open access peer-reviewed

5. Hepatotoxicity by Drugs

By Alejandra Cano Paniagua and Pedro Amariles


Open access peer-reviewed

6. Side Effects of Glucocorticoids

By Irmak Sayın Alan and Bahadır Alan


Open access peer-reviewed

7. New Antidepressant Medication: Benefits Versus Adverse Effects

By Maria Bogdan, Eliza Gofita, Daniela Cornelia Calina, Adina Turcu- Stiolica, Anca Oana Docea, Tudor Adrian Balseanu, Adrian Camen, Gratiela Eliza Popa, Gabriela Rusu, Ina Cristofor, Liliana Pavel and Liliana Mititelu-Tartau


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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