Open access peer-reviewed Edited Volume


Physiology or Pathology


Wojciech Kozubski

Poznań University of Medical Sciences

In the second half of the twentieth century, life expectancy was prolonged, and the number of elderly people increased. The effect of population aging increases in the frequency of neurodegenerative diseases such as Alzheimer's and Parkinson's diseases, epilepsy, and stroke. Also, a higher incidence of infections, autoimmune diseases, and malignant cancers is observed in elderly people. The aging process is difficult to define. Are physiological changes in elderly people controlled by specific genes? Is aging process a pathophysiology affecting different organs with different severity? Finding answers to these questions may help prevent age-related diseases and improve the quality of life of old people. This book was made as a compendium on contemporary challenges in senescence.

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SenescencePhysiology or PathologyEdited by Jolanta Dorszewska

Published: August 30th 2017

DOI: 10.5772/65533

ISBN: 978-953-51-3462-6

Print ISBN: 978-953-51-3461-9

eBook (PDF) ISBN: 978-953-51-4678-0

Copyright year: 2017

Books open for chapter submissions

8485 Total Chapter Downloads

12 Crossref Citations

11 Web of Science Citations

24 Dimensions Citations


Open access peer-reviewed

1. Introductory Chapter: Molecular Basis of Senescence

By Jolanta Dorszewska and Wojciech Kozubski


Open access peer-reviewed

2. Genetic Factors Associated with Longevity in Humans

By Sara Bozzini and Colomba Falcone


Open access peer-reviewed

3. Sunflower Leaf Senescence: A Complex Genetic Process with Economic Impact on Crop Production

By Sebastián Moschen, Agustín I. López Gialdi, Norma Paniego, Paula Fernandez and Ruth Amelia Heinz


Open access peer-reviewed

4. Accelerated Senescence of Cancer Stem Cells: A Failure to Thrive or a Route to Survival?

By Jekaterina Erenpreisa, Kristine Salmina and Mark Steven Cragg


Open access peer-reviewed

5. Aging and Neurological Diseases

By Marta Kowalska, Michal Owecki, Michal Prendecki, Katarzyna Wize, Joanna Nowakowska, Wojciech Kozubski, Margarita Lianeri and Jolanta Dorszewska


Open access peer-reviewed

6. Presenilins Interactome in Alzheimer’s Disease and Pathological Ageing

By Michalina Maria Wężyk and Cezary Żekanowski


Open access peer-reviewed

7. Is Senescence Important in Hepatic Diseases?

By Ruth Pacheco Rivera, Jaime Arellanes Robledo and Jesús Serrano Luna


Open access peer-reviewed

8. Potential Reduction in Mortality Associated with the Shifts of Population Educational Structures in the Czech Republic

By Jitka Rychtaříková and Klára Hulíková Tesárková


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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