Open access peer-reviewed Edited Volume

Systemic Sclerosis

Edited by Mislav Radic

Klinički bolnički centar Split

Systemic sclerosis is a rare autoimmune disease characterized by immunological alterations, small vessel vasculopathy, and skin and other organ fibrosis. Despite progress in the knowledge of pathogenic steps and therapeutic options, when compared with other rheumatic conditions, it shows the lowest life expectancy rate. Early diagnosis is important as early treatment could lead to better outcomes. Great progress has been made in the treatment of specific symptoms; however, there are still no disease-modifying drugs that are able to control the overall disease activity satisfactorily. This book covers the latest knowledge in systemic sclerosis from pathophysiology to clinical presentation and management. Hopefully, this book will be a useful resource to students, residents, rheumatologists, dermatologist, and anyone interested in this fascinating disease.

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Systemic SclerosisEdited by Mislav Radic

Published: October 4th 2017

DOI: 10.5772/63286

ISBN: 978-953-51-3548-7

Print ISBN: 978-953-51-3547-0

eBook (PDF) ISBN: 978-953-51-4632-2

Copyright year: 2017

Books open for chapter submissions

9979 Total Chapter Downloads

5 Crossref Citations

2 Web of Science Citations

9 Dimensions Citations


Open access peer-reviewed

1. Pulmonary Hypertension in Systemic Sclerosis

By Fleur Poelkens, Madelon C. Vonk and Annelies E. van Ede


Open access peer-reviewed

2. Atherosclerosis and Cardiovascular Risk in Systemic Sclerosis

By Sabina Oreska and Michal Tomcik


Open access peer-reviewed

3. Survival, Mortality, Causes of Death and Risk Factors of Poor Outcome

By Manuel Rubio-Rivas


Open access peer-reviewed

4. Nonpharmacological Treatment in Systemic Sclerosis

By Maja Špiritović and Michal Tomčík


Open access peer-reviewed

5. Videocapillaroscopy in Connective Tissue Diseases

By Simone Parisi and Maria Chiara Ditto


Open access peer-reviewed

6. Ophthalmological Manifestations and Tear Investigations in Systemic Sclerosis

By Aniko Rentka, Krisztina Koroskenyi, Jolan Harsfalvi, Zoltan Szekanecz, Gabriella Szucs, Peter Szodoray and Adam Kemeny- Beke


Open access peer-reviewed

7. Biological Therapy in Systemic Sclerosis

By Joana Caetano, Susana Oliveira and José Delgado Alves


Open access peer-reviewed

8. Animal Models of Systemic Sclerosis

By Hana Storkanova and Michal Tomcik


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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