Open access peer-reviewed Edited Volume

Sickle Cell Disease

Pain and Common Chronic Complications

This book addresses a wide range of clinically relevant topics and issues in sickle cell disease. This is written by experts in their own field offering a robust, engaging discussion about the presentations and mechanisms of actions in the multiple complications associated with sickle cell disease. This first of the series addresses pain, which is considered the hallmark of sickle cell presentation. It looks at the basic mechanism of pain in sickle cell disease. A more detailed review of precision medicine gives a clear well laid out presentation that is incisive and yet gives in-depth detail relevant to both the clinician and the researcher in the basic laboratory. The same pattern is shown in the discussion on respiratory, cardiac and neurological complications. The 14 chapters also include an overview of sickle cell disease especially in the paediatric age. The content is organized into well-designed broad sections on overview regarding diagnosis including point of care and the role of digital apps in patient management. A key aspect of the book is the opportunity it affords expert physicians to express well-reasoned opinions regarding complex issues in sickle cell disease. The readership would find that it provides a well-described, concise and immediate applicable answers to complex questions. This is highly recommended for scientists and clinicians alike.

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Sickle Cell DiseasePain and Common Chronic ComplicationsEdited by Baba P.D. Inusa

Published: November 10th 2016

DOI: 10.5772/62012

ISBN: 978-953-51-2767-3

Print ISBN: 978-953-51-2766-6

eBook (PDF) ISBN: 978-953-51-4154-9

Copyright year: 2016

Books open for chapter submissions

25489 Total Chapter Downloads

9 Crossref Citations

6 Web of Science Citations

23 Dimensions Citations


Open access peer-reviewed

1. Introductory Chapter: Introduction to the History, Pathology and Clinical Management of Sickle Cell Disease

By Baba Inusa, Maddalena Casale and Nicholas Ward


Open access peer-reviewed

2. A Global Perspective on Milestones of Care for Children with Sickle Cell Disease

By Laura Sainati, Maria Montanaro and Raffaella Colombatti


Open access peer-reviewed

3. New Perspectives in Prenatal Diagnosis of Sickle Cell Anemia

By Ebru Dündar Yenilmez and Abdullah Tuli


Open access peer-reviewed

4. Point‐of‐Care Testing in Sickle Cell Disease

By Julie Kanter


Open access peer-reviewed

5. Mechanisms of Pain in Sickle Cell Disease

By Anupam Aich, Alvin J Beitz and Kalpna Gupta


Open access peer-reviewed

6. The Cardiomyopathy of Sickle Cell Disease

By Omar Niss and Charles T. Quinn


Open access peer-reviewed

7. Pulmonary Complications and Lung Function Abnormalities in Children with Sickle Cell Disease

By Anne Greenough


Open access peer-reviewed

8. Neurological Complications and MRI

By Jamie M. Kawadler and Fenella J. Kirkham


Open access peer-reviewed

9. Asthma, Airway Hyperresponsiveness, and Lower Airway Obstruction in Children with Sickle Cell Disease

By Aravind Yadav, Ricardo A. Mosquera and Wilfredo De Jesus Rojas


Open access peer-reviewed

10. Leg Ulceration in Sickle Cell Disease: An Early and Visible Sign of End‐Organ Disease

By Aditi P. Singh and Caterina P. Minniti


Open access peer-reviewed

11. Stem Cell Transplantation in Patients with Sickle Cell Disease

By Murtadha Al-Khabori, Mohammed Al-Huneini and Abdulhakim Al- Rawas


Open access peer-reviewed

12. Precision Medicine for Sickle Cell Disease: Discovery of Genetic Targets for Drug Development

By Betty S. Pace, Nicole H. Lopez, Xingguo Zhu and Biaoru Li


Open access peer-reviewed

13. Phytotherapy and the Relevance of Some Endogenous Antioxidant Enzymes in Management of Sickle Cell Diseases

By Israel Sunmola Afolabi, Iyanuoluwa O. Osikoya and Adaobi Mary-Joy Okafor


Open access peer-reviewed

14. Digital Health Interventions (DHIs) to Support the Management of Children and Adolescents with Sickle‐Cell Disease

By Stephan Lobitz, Kristina Curtis and Kai Sostmann


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI
  • BKCI

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